Jekiseni jekiseni

Zvemukati

• Golimumab jekiseni (Simponi) inoshandiswa kubvisa zviratidzo zvehumwe autoimmune kusagadzikana (mamiriro umo immune system inorwisa zvikamu zvine hutano zvemuviri uye inokonzeresa kurwadziwa, kuzvimba, uye kukuvara) kusanganisira:
• Golimumab jekiseni (Simponi Aria) inoshandiswa zvakare kugadzirisa zviratidzo zvehumwe hutachiona hwe autoimmune hunosanganisira:
• Usati washandisa jekiseni regolimumab,
• Jekiseni reGolimumab rinogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukasira kana tora rubatsiro rwechimbichimbi.

Kushandisa jekiseni regolimumab kunogona kudzikisira kugona kwako kurwisa hutachiona uye kuwedzera njodzi yekuti uchawana hutachiona hwakakomba, kusanganisira zvakanyanya fungal, bhakitiriya, kana hutachiona hutachiona hunopararira nemuviri. Zvirwere izvi zvingangoda kurapwa muchipatara uye zvinogona kukonzera kufa. Udza chiremba wako kana iwe uchiwanzo kuwana chero hutachiona hutachiona kana kana iwe uchifunga kuti ungave uine chero hutachiona hutachiona izvozvi. Izvi zvinosanganisira hutachiona hushoma (sekucheka kana maronda akavhurika), hutachiona hunouya nekuenda (hwakadai maronda anotonhora) uye hutachiona husingaperi husingaendi. Uyezve udza chiremba wako kana iwe kana wakambove nechirwere cheshuga, hutachiona hwehutachiona hwehutachiona (HIV), wakawana immunodeficiency syndrome (AIDS), kana chero imwe mamiriro ezvinhu anokanganisa immune system yako. Iwe unofanirwa zvakare kuudza chiremba wako kana iwe uchigara kana kuti wakambogara munzvimbo dzakadai seOhio kana Mississippi rwizi rwizi uko kwakanyanya hutachiona hutachiona hwakawanda. Kumbira chiremba wako kana iwe usina chokwadi kana hutachiona uhwu hwakajairika munharaunda yako. Udza chiremba wako kana uri kutora mishonga inoderedza mashandiro ezvirwere zvemuviri seizvi zvinotevera: abatacept (Orencia); anakinra (Kineret); methotrexate (Rheumatrex); rituximab (Rituxan); steroid inosanganisira dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone) uye prednisone; tocilizumab (Actemra); uye vamwe TNF-blockers senge adalimumab (Humira), certolizumab (Cimzia), etanercept (Enbrel), uye infliximab (Remicade).

Chiremba wako anokucherechedza iwe nezviratidzo zvehutachiona panguva uye mushure mekurapa kwako. Kana iwe uine chero cheanotevera zviratidzo usati watanga kurapwa kwako kana kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge waita kurapwa, dana chiremba wako nekukurumidza: kushaya simba; vangadikitira; huro inorwadza; kukosora; kukosora maburi eropa; kupindwa nechando; kuonda; kuneta kwakanyanya; manyoka; kurwadziwa mudumbu; inodziya, tsvuku, kana inorwadza ganda; maronda paganda; zvinorwadza, zvakaoma, kana kazhinji weti; kana zvimwe zviratidzo zvehutachiona.

Iwe unogona kutapukirwa neTBerculosis (TB, rudzi rwehutachiona hutachiona) kana hepatitis B (rudzi rwechiropa chirwere) asi usina kana zviratidzo zvechirwere. Mune ino kesi, jekiseni yegolimumab inogona kuwedzera njodzi yekuti hutachiona hwako huchawedzera uye uchaita zviratidzo. Chiremba wako achaita ongororo yeganda kuti aone kana uine hutachiona hweTB husingaite uye anogona kuraira kuongororwa kweropa kuti aone kana uine hutachiona hwehepatitis B. Kana zvichidikanwa, chiremba wako achakupa mishonga yekurapa hutachiona usati watanga kushandisa jekiseni regolimumab. Udza chiremba wako kana wakambove neTB kana hepatitis B, kana wakashanyira nyika ipi neipi iyo TB yakajairika, kana kana wakambove pedyo nemunhu ane TB. Kana iwe uine chero anotevera ezviratidzo zveTB, kana kana iwe ukaita chero eaya maratidziro panguva yekurapwa kwako, fonera chiremba wako nekukasika: chikosoro, kuonda, kurasikirwa kwemhasuru toni, kana fivha. Zvakare fonera chiremba wako nekukasira kana uine chimwe chezviratidzo zvehepatitis B kana kana iwe uchikura chimwe chezviratidzo izvi panguva kana mushure mekurapwa kwako: kuneta zvakanyanya, kuita yero kweganda kana maziso, kurasikirwa nenzara, kuda kurutsa kana kurutsa, tsandanyama aches, weti yakasviba, kufamba-kweuvara-ura kufamba, fivha, kutonhora, kurwadziwa mudumbu, kana kuputika.

Vamwe vana, vachiri kuyaruka, uye vechidiki vakura vakagamuchira jekiseni regolimumab nemimwe mishonga yakafanana vakagadzira kenza dzakakomba kana kutyisidzira hupenyu dzinosanganisira lymphoma (kenza inotanga mumasero anorwisa hutachiona). Vamwe vechidiki uye vechidiki varume vakuru vakatora golimumab kana mishonga yakafanana vakagadzira hepatosplenic T-cell lymphoma (HSTCL), chirwere chakakomba chekenza chinowanzo kukonzera kufa mukati menguva pfupi yenguva. Vazhinji vevanhu vakagadzira HSTCL vanga vachirapwa chirwere cheCrohn (mamiriro umo muviri unorwisa kumhara kwegwara rekudya, zvichikonzera marwadzo, manyoka, kuonda, nefivha) kana ulcerative colitis (mamiriro anokonzera kuzvimba nemaronda. mumutsara wekoloni [ura hukuru] uye rectum) ne golimumab kana mushonga wakafanana pamwe nemumwe mushonga unonzi azathioprine (Imuran) kana 6-mercaptopurine (Purinethol). Vana nevechiri kuyaruka havafanirwe kugamuchira jekiseni re golimumab, asi mune dzimwe nguva, chiremba anogona kusarudza kuti jekiseni regolimumab ndiyo mishonga yakanakisa yekurapa mamiriro emwana. Kana jekiseni reg golimumab rakatemerwa mwana wako, iwe unofanirwa kutaura nachiremba wemwana wako nezve njodzi uye zvakanakira kushandisa mushonga uyu. Kana mwana wako akatanga chero eaya maratidziro panguva yekurapwa kwake, danai chiremba wake nekukasira: kusanzwisisika kuonda kuzvimba gland mumutsipa, underarms, kana kugomera; kana kupwanya kuri nyore kana kubuda ropa.

Chiremba wako kana wemishonga achakupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa nejojo ​​yeglamumumab uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm)kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekugamuchira jekiseni re golimumab.

Golimumab jekiseni (Simponi) inoshandiswa kubvisa zviratidzo zvehumwe autoimmune kusagadzikana (mamiriro umo immune system inorwisa zvikamu zvine hutano zvemuviri uye inokonzeresa kurwadziwa, kuzvimba, uye kukuvara) kusanganisira:

• rheumatoid arthritis (mamiriro umo muviri unorwisa mitezo yawo uchikonzera kurwadziwa, kuzvimba, uye kurasikirwa nebasa) pamwe ne methotrexate (Otrexup, Rasuvo, Trexall) muvanhu vakuru,
• ankylosing spondylitis (mamiriro umo muviri unorwisa majoini emuzongoza pamwe nedzimwe nzvimbo zvichikonzera kurwadziwa nekukuvara kwemajoini) muvanhu vakuru,
• psoriatic arthritis (mamiriro anokonzera kurwadza kwemajoini uye kuzvimba uye zviyero paganda) ega kana musanganiswa nemethotrexate muvanhu vakuru, uye
• ulcerative colitis (chirwere chinokonzeresa kuzvimba uye maronda mumutsara wekoloni [ura hukuru] uye rectum) apo mimwe mishonga nemishonga hazvina kubatsira kana kutadza kubvumidzwa.

Golimumab jekiseni (Simponi Aria) inoshandiswa zvakare kugadzirisa zviratidzo zvehumwe hutachiona hwe autoimmune hunosanganisira:

• rheumatoid arthritis (mamiriro umo muviri unorwisa mitezo yawo uchikonzera kurwadziwa, kuzvimba, uye kurasikirwa nebasa) pamwe ne methotrexate (Otrexup, Rasuvo, Trexall) muvanhu vakuru,
• ankylosing spondylitis (mamiriro umo muviri unorwisa majoini emuzongoza pamwe nedzimwe nzvimbo zvichikonzera kurwadziwa nekukuvara kwemajoini) muvanhu vakuru,
• psoriatic arthritis (mamiriro anokonzeresa kurwadza kwemajoini uye kuzvimba uye zviyero paganda) muvanhu vakuru nevana makore maviri ezera nekure,
• polyarticular juvenile idiopathic arthritis (PJIA; mhando yehudiki arthritis inobata majoini mashanu kana anopfuura mukati memwedzi mitanhatu yemamiriro acho, zvichikonzera kurwadziwa, kuzvimba, uye kurasikirwa kwebasa) muvana vane makore maviri ekuberekwa zvichikwira.

Golimumab iri mukirasi yemishonga inonzi tumor necrosis factor (TNF) inhibitors. Inoshanda nekudzivirira chiito cheTNF, chinhu mumuviri chinokonzera kuzvimba.

Jekiseni reGolimumab rinouya semhinduro (mvura) kupinza subcutaneous (pasi peganda) kana kupinda mukati (mukati mutsinga). Kana golimumab ikapihwa subcutaneously kurapa rheumatoid arthritis, psoriatic arthritis, kana ankylosing spondylitis, inowanzo kupihwa kamwe pamwedzi. Kana golimumab ikapihwa pasi pechiso kurapa ulcerative colitis, inowanzo kupihwa kamwe chete pasvondo roga roga pamatanho maviri ekutanga (pavhiki 0 nevhiki 2) uyezve kamwe chete mumasvondo mana mushure. Kana golimumab ikapihwa musinga nachiremba nachiremba kana mukoti munzvimbo yekuchengetedza hutano kurapa rheumatoid arthritis, ankylosing spondylitis. psoriatic arthritis, kana polyarticular vechidiki idiopathic arthritis, inowanzo kupihwa pamusoro pemaminetsi makumi matatu kamwe chete pasvondo roga roga pamatanho maviri ekutanga (pavhiki 0 nevhiki 2) uyezve kamwe chete mumasvondo mana mushure. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Shandisa jekiseni regirimumab chaizvo sezvakarairwa. Usaise jekiseni zvakanyanya kana zvishoma kana kuijowa kakawanda kupfuura zvakatemwa nachiremba wako.

Iwe uchagamuchira yako yekutanga subcutaneous dose yeiyo golimumab jekiseni muhofisi yako yechiremba. Mushure meizvozvo, chiremba wako anogona kukubvumidza kuti ujove golimumab iwe kana kuita shamwari kana hama inoita majekiseni. Usati washandisa jekiseni regolimumab iwe kekutanga, verenga yakanyorwa mirairo inouya nayo. Kumbira chiremba wako kana wemishonga kuti akuratidze kana munhu uyo ​​achange achibaisa mushonga kuti anoijowa sei.

Golimumab jekiseni (Simponi) inouya mune yakasarudzika majekiseni uye auto-jekiseni zvishandiso zve subcutaneous jekiseni. Shandisa sirinji yega yega kana chishandiso kamwe chete uye jekiseni mhinduro yese mujekiseni kana muchigadzirwa. Kunyangwe paine imwe mhinduro yasara mujekiseni kana peni mushure mekubaya jekiseni, usabaya zvakare. Rasa majekiseni nemidziyo yakashandiswa mumudziyo unodzivira. Taura nachiremba wako kana wemabhizimusi nezve maratidziro aungaita mudziyo usingadzivirirwe.

Bvisa sirinji yakasarudzika kana pre-autoinjector kubva mufiriji uye ibvumidze kudziya kune tembiricha yemukamuri kwemaminitsi makumi matatu usati waishandisa. Ibudise kunze kwekatoni rayo, uye ibvumidze kuti igare pane imwe nzvimbo yakati sandara kuti igone kudziya kutembiricha yemukati. Usaedze kudziya mushonga nekuupisa mu microwave, uchiisa mumvura inopisa, kana neimwe nzira.

Usabvisa kapu kubva muchigadzirwa che auto-jekiseni kana chifukidziro kubva pasiringi yakasarudzwa apo mushonga uchidziya. Iwe unofanirwa kubvisa chivharo kana kuvhara kwete anopfuura maminetsi mashanu usati wajowa mushonga. Usatsiva chivharo kana chivharo mushure mekuchibvisa. Usashandise sirinji kana chishandiso kana iwe ukachiwisira pasi icho chisina kuvharwa kana kufukurwa.

Usambofa wakazunza auto-jekiseni chishandiso kana iyo yakasarudzika jekiseni. Izvi zvinogona kukuvadza mushonga.

Nguva dzose tarisa jekiseni regirimumab usati waijekesa. Tarisa zuva rekupera rakadhindwa pane auto-jekiseni chishandiso kana katoni uye usashandise mushonga kana zuva rekupera rapfuura. Usashandise sirinji yakasarudzika kana auto-jekiseni mudziyo unoratidzika kunge wakakuvadzwa, uye usashandise mudziyo wekubaya-auto kana chisimbiso chekuchengetedza chapwanyika. Tarisa nepahwindo rekutarisa pane yakasarudzika sirinji kana mudziyo-wekubaya-mota. Mvura irimo mukati inofanira kunge yakajeka uye isina ruvara kana kuti yero yakati siyanei, asi inogona kunge iine zvidiki zvidiki zvichena kana bota remhepo. Usashandise sirinji kana chishandiso kana mushonga wacho uine makore kana wakasviba kana uine zvidimbu zvikuru.

Nzvimbo yakanakisa yekujekesa golimumab ndiyo kumberi kwechidya chepakati. Nekudaro, iwe unogona zvakare jekiseni golimumab mudumbu rako rezasi pazasi peguvhu rako, kunze kwenzvimbo ye2 inch (5 centimeter) yakatenderedza guvhu. Kana mumwe munhu achikupa jekiseni, munhu iyeye anogona zvakare kupinza mushonga mumaoko ako ekumusoro. Sarudza imwe nzvimbo yekubairira mushonga mazuva ese. Usapinda jekiseni munzvimbo ine ganda rako rakatsvuka, rakapwanywa, nyoro, rakaomarara kana rine mitsara, kana paunenge uine mavanga kana mamaki.

Jekiseni reGolimumab rinogona kubatsira kudzora mamiriro ako asi risingarape. Enderera kushandisa jekiseni regoriyumu kunyange kana uchinzwa zvakanaka. Usarega kushandisa jekiseni regiramu usingatauri nachiremba wako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati washandisa jekiseni regolimumab,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune jekiseni rejolimumab, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujojo ye golimumab. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa. Uyezve udza chiremba wako kana iwe kana munhu achange achikubatsira jekiseni jekiseni regolimumab ari alejiki kune latex kana rubber.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa muchikamu CHINOKOSHA CHENYENZO uye chero ipi yemishonga inotevera: anticoagulants ('blood thinner') senge warfarin (Coumadin), cyclosporine (Gengraf, Neoral, Sandimmune), uye theophylline (Theochron, Theolair, Uniphyl ). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe kana wakambove nekenza, psoriasis (chirwere cheganda umo tsvuku tsvuku inonamira paganda), chero mamiriro ezvinhu anokanganisa system yako yetsinga senge multiple sclerosis (MS, chirwere chisina tsinga shanda nemazvo zvichikonzera kushaya simba, kupera simba, kurasikirwa kwekubatana kwetsandanyama uye matambudziko nekuona, kutaura, uye kudzora dundira) kana Guillain Barre syndrome (kushaya simba, kurira, uye kugona kuora mitezo nekuda kwekukuvara kwetsinga). , kana chirwere chemwoyo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa.Kana iwe ukava nepamuviri iwe uchishandisa girimumab jekiseni, fonera chiremba wako. Kana iwe ukashandisa jekiseni regolimumab panguva yako yepamuviri, ita chokwadi chekutaura nachiremba wemwana wako nezve izvi mushure mekunge mwana wako azvarwa. Mwana wako angangoda kugamuchira mamwe majekiseni mushure menguva dzose.
• hauna majekiseni pasina kutaura nachiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Baya josi rakarasika nekukurumidza kana uchinge warangarira, uye wozobaya rako rinotevera panguva yakagara yakarongwa. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usapinda jekiseni repaviri kuti uwane iyo yakarasika. Fonera chiremba wako kana wemishonga kana iwe usingazive nguva yekubaya jekiseni regirimumab.

Jekiseni reGolimumab rinogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kutsvuka, kuchenesa, kupwanya, kurwadziwa, kana kuzvimba munzvimbo iyo jekiseni regoriyamu
• dzungu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukasira kana tora rubatsiro rwechimbichimbi.

• kurwadziwa pachipfuva
• mweya wekufema
• kuzvimba kwemakumbo kana makumbo ezasi
• maonero anochinja
• kushaya simba, chiveve, kana kurira kwemaoko kana makumbo
• matsvuku makwapa makwapa kana mapundu-akazadzwa mapundu paganda
• mhoni
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• kupwanya kuri nyore kana kubuda ropa
• ganda rakachenuruka
• mapundu pamatama kana chimwe chikamu chemuviri
• Kunzwisisa zuva
• kurwadza kwemajoini
• mikoko
• kuzvimba kwemaziso, kumeso, miromo, rurimi, muromo, kana huro
• kunetseka kufema kana kumedza

Jekiseni reGolimumab rinogona kuwedzera njodzi yekurapa melanoma (rudzi rwegomarara reganda), lymphoma (kenza inotanga mumasero anorwisa hutachiona), leukemia (gomarara rinotanga mumasero machena eropa), uye mamwe marudzi ekenza kupfuura vanhu usatambira mushonga. Taura nachiremba wako nezve njodzi dzekugamuchira jekiseni re golimumab.

Golimumab jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze mufiriji asi usazviisa chando. Chengetedza mishonga mumakatoni ekutanga kuti uichengetedze kubva pachiedza.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Usarega mumwe munhu achishandisa mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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