Munyori: Janice Evans
Zuva Rekusika: 28 Chikunguru 2021
Gadziridza Zuva: 16 Mbudzi 2024
Anonim
Lurasidone Review - Mechanism of Action, Side Effects and Clinical Pearls
Vhidhiyo: Lurasidone Review - Mechanism of Action, Side Effects and Clinical Pearls

Zvemukati

Yambiro yakakosha kune vakuru vakuru vane dementia:

Zvidzidzo zvakaratidza kuti vakuru vakura vane dementia (chirwere chehuropi chinokanganisa kugona kurangarira, kufunga zvakajeka, kutaurirana, uye kuita zviitiko zvezuva nezuva uye izvo zvinogona kukonzera shanduko mumafungire nehunhu) vanotora antipsychotic (mishonga yehurwere hwepfungwa) senge lurasidone vane mukana wakawedzerwa wekufa panguva yekurapwa. Vakwegura vakuru vane dementia vanogona zvakare kuve nemukana wakakura wekurohwa nesitiroko kana kubatira panguva yekurapwa neantipsychotic.

Lurasidone haina kubvumidzwa neKudya neDrug Administration (FDA) yekurapa kusagadzikana kwehunhu kune vakuru vakuru vane dementia. Taura nachiremba uyo akaraira uyu mushonga kana iwe, nhengo yemhuri, kana mumwe munhu waunotarisira aine kuora mwoyo uye achitora lurasidone. Kuti uwane rumwe ruzivo shanyira iyo FDA webhusaiti: http://www.fda.gov/Drugs

Yambiro yakakosha kune vanhu vane kushushikana:

Chiverengero chidiki chevana, vachiri kuyaruka, uye vechidiki vechidiki (kusvika pamakore makumi maviri nemana ekuberekwa) vakatora mishonga yekushushikana mukati mezvidzidzo zvekiriniki vakava kuzviuraya (kufunga nezvekuzvikuvadza kana kuzviuraya kana kuronga kana kuyedza kuzviita). Vana, vachiri kuyaruka, uye vechidiki vakuru vanotora mishonga yekudzvinyirira kurapa kushushikana kana zvimwe zvirwere zvepfungwa vangangoita mukana wekuzviuraya pane vana, vechidiki, uye vechidiki vasingatore mishonga yekudzvinyirira kurapa aya mamiriro. Nekudaro, nyanzvi hadzina chokwadi nezve hukuru hwenjodzi iyi uye kuti yakawanda sei iyo inofanirwa kutariswa mukusarudza kuti mwana kana wechidiki anofanira kutora chinodzvinyirira. Vana vari pasi pemakore gumi ekuberekwa havafanirwe kutora lurasidone kurapa kushushikana, asi mune dzimwe nguva, chiremba anogona kusarudza kuti lurasidone ndiwo mushonga wakanakisa wekurapa mamiriro emwana.


Iwe unofanirwa kuziva kuti hutano hwako hwepfungwa hunogona kuchinja nenzira dzisingatarisirwi paunotora lurasidone yekurapa kushushikana kana zvimwe chirwere chepfungwa kunyangwe iwe uri mukuru anopfuura makore makumi maviri nemana ekuberekwa. Unogona kuzviuraya, kunyanya pakutanga kwekurapwa kwako uye chero nguva iyo dhizaini yako ichiwedzera kana kuderera. Iwe, mhuri yako, kana muchengeti wako unofanira kufonera chiremba wako ipapo ipapo kana iwe ukawana chero yeapi anotevera zviratidzo: kutsva kana kuwedzera kuora mwoyo; kufunga nezvekukuvadza kana kuzviuraya iwe, kana kuronga kana kuyedza kuzviita; kunetseka zvakanyanya; kusagadzikana; kutya kwekutya; kunetseka kurara kana kuramba wakarara; hutsinye hunhu; kutsamwa; kuita pasina kufunga; kusagadzikana kwakanyanya; uye kupenga kusingafadzi. Iva nechokwadi chekuti mhuri yako kana muchengeti anoziva kuti ndezvipi zviratidzo zvingave zvakakomba saka vanogona kufonera chiremba kana iwe usingakwanise kutsvaga kurapwa iwe wega.

Mubatsiri wako wehutano achada kukuona iwe kazhinji paunenge uchitora lurasidone, kunyanya pakutanga kwekurapa kwako. Ive neshuwa yekuchengeta ese maahofisi ekushanyira kuhofisi nachiremba wako.


Kunyangwe uine zera ripi, usati watora mushonga wekudzvinyirira, iwe, mhuri yako, kana muchengeti wako unofanira kutaura nachiremba wako nezve njodzi uye mabhenefiti ekurapa mamiriro ako neanodzvinyirira kana nemamwe marapirwo. Iwe unofanirwa zvakare kutaura nezve njodzi uye zvakanakira kusarapa mamiriro ako. Iwe unofanirwa kuziva kuti kuve nekuora mwoyo kana chimwe chirwere chepfungwa kunowedzera zvakanyanya njodzi yekuti uchazviuraya. Iyi njodzi yakakwira kana iwe kana chero munhu mumhuri mako uine kana wakambove nebipolar kusagadzikana (mafungiro anoshanduka kubva pakuora mwoyo kuenda mukufara zvisina kujairika) kana mania kana akafunga nezvazvo kana kuyedza kuzviuraya. Taura nachiremba wako nezve ako mamiriro, zviratidzo, uye wega uye zvemhuri nhoroondo yekurapa. Iwe nachiremba wako muchasarudza kuti ndeupi rudzi rwekurapa rwakakukodzera.

Lurasidone inoshandiswa kurapa zviratidzo zvechichichiphrenia (chirwere chepfungwa chinokanganisa kufunga kana kujairika kufunga, kurasikirwa kwekufarira muhupenyu, uye kusimba kana kusanzwisisika manzwiro) muvakuru nevana vane makore gumi nematanhatu zvichikwira. Iyo inoshandiswawo kurapa kushushikana muvakuru uye vana vane makore gumi ekuberekwa uye vakuru vane bipolar disorder (manic depression disorder; chirwere chinokonzera zvikamu zvekushungurudzika, episodes of mania, uye mamwe mamood asina kujairika). Lurasidone inoshandiswa zvakare pamwe ne lithiamu (Lithobid) kana valproate (Depacon) kurapa kushushikana kune vanhu vakuru vane bipolar disorder. Lurasidone iri mukirasi yemishonga inonzi atypical antipsychotic. Inoshanda nekushandura chiitiko cheimwe yakasarudzika zvinhu muuropi.


Lurasidone inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe nekudya (inokwana mazana matatu emakoriori) kamwe pazuva. Tora lurasidone panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora lurasidone chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Lurasidone inodzora schizophrenia uye kushushikana mune vanhu vane bipolar kusagadzikana asi hazvirape aya mamiriro. Zvinogona kutora mavhiki akati wandei kana kupfuura usati wanzwa kubatsirwa kuzere kwelurasidone. Ramba uchitora lurasidone kunyangwe iwe uchinzwa zvakanaka. Usarega kutora lurasidone usina kutaura nachiremba wako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora lurasidone,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune lurasidone, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi e-lurasidone. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uri kutora carbamazepine (Carbatrol, Epitol, Tegretol); clarithromycin (Biaxin, muPrevpac); ketoconazole; mibefradil; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, muRifamate, muRifater); ritonavir (Norvir); Wort St. kana voriconazole (Vfend). Chiremba wako angangokuudza kuti usatore lurasidone kana iwe uri kutora imwe yemishonga iyi.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: antidepressants; antihistamines; atazanavir (Reyataz); bosentan (Tracleer); diltiazem (Cardizem, Cartia, Taztia, Tiazac, nevamwe); efavirenz (Sustiva, muAtripla); erythromycin (EES, E-Mycin, Ery-Tab, vamwe); etravirine (kusagadzikana); fluconazole (Diflucan); indinavir (Crixivan); ipratropium (Atrovent, muCombivent, muDuoneb); itraconazole (Sporanox); mishonga yekudzora kushushikana, sedatives, yekurara mapiritsi, kana tranquilizers; mishonga yekudzivirira kuwedzera kweropa; mishonga yeglaucoma, chirwere chinoputira ura, kufamba kwechirwere, myasthenia gravis, chirwere chePasinson, maronda, kana matambudziko eweti; modafinil (Provigil); nafcillin; nefazodone; nelfinavir (Viracept); phenobarbital; pioglitazone (Actos, muDuetact, muActoplus Met); rifabutin (Mycobutin); kana verapamil (Calan, Verelan, vamwe, muTarka); Mimwe mishonga inogona zvakare kubatana ne lurasidone, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe wakamboshandisa kana wakamboshandisa zvinodhaka zvemumugwagwa kana kushandisa zvakanyanyisa mishonga yemushonga uye kana iwe uine kana wakamborohwa nesitiroko; kushumirwa (TIA); kurwadziwa muchipfuva, chirwere chemwoyo, kana chirwere chemwoyo; kurova kwemoyo zvisina kujairika; kutadza kwemoyo; Chirwere cheParkinson (kusagadzikana kwehurongwa hwemitsipa hunokonzera matambudziko nekufamba, kudzora mhasuru, uye kuenzanisa); Chirwere cheAlzheimer (chirwere chehuropi chinoparadza zvishoma nezvishoma ndangariro uye kugona kufunga, kudzidza, kutaurirana nekubata zviitiko zvezuva nezuva); pfari; dementia; kenza yemazamu; kunetseka kuchengeta yako chiyero; chero mamiriro ezvinhu anoita kuti zvikunetse kumedza; yakakwira kana yakaderera BP; yakakwira prolactin mazinga; huwandu hwemafuta (cholesterol uye triglycerides) muropa rako; nhamba yakaderera yemasero machena eropa; itsvo chirwere; chirwere chechiropa; shuga yakakwira muropa; kana kana iwe kana chero mumwe mumhuri yako ane kana akambove nechirwere cheshuga. Udza chiremba wako kana uine kurutsa kwakanyanya kana manyoka kana zviratidzo zvekushaikwa kwemvura izvozvi, kana kana iwe ukava nezviratidzo izvi chero nguva panguva yekurapwa kwako. Uyezve udza chiremba wako kana iwe wakambomira kutora mushonga wehurwere hwepfungwa nekuda kwemhedzisiro yakaipa.
  • udza chiremba wako kana iwe uri nepamuviri, kunyanya kana iwe uri mumwedzi mishoma yapfuura yekubata kwako, kana kana iwe uronga kuve nepamuviri kana kuyamwisa. Kana iwe ukava nepamuviri uchitora lurasidone, danaidza chiremba wako. Lurasidone inogona kukonzera matambudziko muvana vachangozvarwa zvichitevera kuburitswa kana ikatorwa mukati memwedzi yekupedzisira yenhumbu.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora lurasidone.
  • iwe unofanirwa kuziva kuti lurasidone inogona kukuita iwe kukotsira. Usatyaire mota kana kushandisa michina ine njodzi kusvikira iwe waziva kuti uyu mushonga unokubata sei.
  • iwe unofanirwa kuziva kuti iwe unogona kusangana ne hyperglycemia (inowedzera mushuga yeropa rako) paunenge uchitora mushonga uyu, kunyangwe kana usati uine chirwere cheshuga. Kana iwe uine schizophrenia, iwe unowanzo kuve nechirwere cheshuga kupfuura vanhu vasina schizophrenia, uye kutora lurasidone kana mishonga yakafanana kunogona kuwedzera njodzi iyi. Udza chiremba wako nekukasira kana uine chimwe chezviratidzo zvinotevera paunenge uchitora lurasidone: nyota yakanyanyisa, kuita weti zvakanyanya, nzara yakanyanyisa, kuona kwakashata, kana kushaya simba. Zvakakosha kusheedza chiremba wako nekukurumidza kana uchinge uine chero cheizvi zviratidzo, nekuti shuga yepamusoro yeropa inogona kukonzera chirwere chakakomba chinonzi ketoacidosis. Ketoacidosis inogona kutyisidzira hupenyu kana ikasarapwa padanho rekutanga. Zviratidzo zve ketoacidosis zvinosanganisira kuoma muromo, kuda kurutsa uye kurutsa, kufema kwekufema, mweya unonhuwira muchero, uye kudzikira kwekuziva.
  • iwe unofanirwa kuziva kuti lurasidone inogona kukonzera dzungu, hurema, uye kupera simba paunosimuka nekukurumidza kubva panzvimbo yekunyepa. Izvi zvinowanzoitika kana iwe ukatanga kutora lurasidone. Kuti ubatsire kunzvenga dambudziko iri, simuka pamubhedha zvishoma nezvishoma, uchizorora tsoka dzako pasi kwemaminetsi mashoma usati wasimuka.
  • iwe unofanirwa kuziva kuti lurasidone inogona kuita kuti zviomere muviri wako kutonhorera kana uchipisa zvakanyanya. Udza chiremba wako kana iwe uchironga kuita maekisesaizi kana kuratidzwa kune kwakanyanya kupisa.
  • iwe unofanirwa kuziva kuti lurasidone inogona kukonzera kuwedzera kwehuremu. Izvo zvakakosha kuti uremu hwako hutariswe nguva nenguva paunenge uchitora mushonga uyu.

Usadye huwandu hwakawanda hwemuzambiringa kana kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Tora dosi rakarasika nechikafu (ingangoita mazana matatu emazana macalorie) nekukurumidza paunenge uchirangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Lurasidone inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • dzungu, kunzwa kusagadzikana, kana kunetsekana nekuchengetedza mwero wako
  • kushushikana
  • kushaya simba
  • kuneta
  • kusagadzikana
  • kuzunza kusingadzoreki nhengo yemuviri
  • kufamba kunonoka kana kufamba-famba
  • kusvotwa
  • kurutsa
  • nzara inoshanduka
  • kuwedzera mate
  • kuwedzera zamu kana kubuda
  • kunonoka kana kupotsa kuenda kumwedzi
  • kudzikira kugona pabonde

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, kana izvo zvakanyorwa mune ZVINOKOSHA ZVENYENZO uye ZVINOKOSHA ZVINONYANYA, daidza chiremba wako nekukasira:

  • pfari
  • kuzvimba kwechiso, huro, rurimi, miromo, maziso, maoko, tsoka, makumbo, kana makumbo ezasi
  • hoarseness
  • kunetseka kumedza kana kufema
  • mweya wekufema
  • kurova kwemoyo zvisina kujairika
  • kurwadziwa pahuro, fivha, kukosora, kutonhora, uye zvimwe zviratidzo zvehutachiona
  • fivha, kudikitira, kuvhiringidzika, kukurumidza kana kusarongeka kwemoyo, uye kuomarara kwemhasuru
  • kufamba zvisina kujairika kwechiso chako kana muviri wausingakwanise kudzora
  • kudonha

Lurasidone inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwebazi kuti atarise mhinduro yemuviri wako kune lurasidone.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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