Munyori: William Ramirez
Zuva Rekusika: 17 Gunyana 2021
Gadziridza Zuva: 13 Mbudzi 2024
Anonim
Axitinib plus pembrolizumab in advanced RCC
Vhidhiyo: Axitinib plus pembrolizumab in advanced RCC

Zvemukati

Axitinib inoshandiswa yoga kurapa renal cell carcinoma (RCC, rudzi rwekenza runotanga mumasero eitsvo) muvanhu vasina kurapwa zvinobudirira nemumwe mushonga. Axitinib inoshandiswa pamwe chete ne avelumab (Bavencio) kana pembrolizumab (Keytruda) kurapa yakakwira renal cell carcinoma. Axitinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.

Axitinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kaviri pazuva. Tora axitinib kwakatenderedza nguva dzakafanana zuva rega rega, anenge maawa gumi nemaviri akaparadzaniswa. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora axitinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara negirazi remvura; usatsemure, kutsenga, kana kuvapwanya.


Kana iwe ukarutsa mushure mekutora axitinib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kukutangisa pane yakaderera dosi yeaxitinib uye zvishoma nezvishoma wedzera yako dosi, kwete kanopfuura kamwe chete kwevhiki mbiri. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye chero mhedzisiro iwe yaungasangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora axitinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora axitinib usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora axitinib,

  • udza chiremba wako uye wemishonga kana iwe uri weergergic kune axitinib, chero mimwe mishonga, kana chimwe chezvinhu zvinoshandiswa mumapiritsi eaxitinib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: bosentan (Tracleer); carbamazepine (Carbatrol, Epitol, Tegretol); clarithromycin (Biaxin, muPrevpac); itraconazole (Sporanox); ketoconazole (Nizoral); mishonga yekurapa HIV / AIDs inosanganisira atazanavir (Reyataz), efavirenz (Sustiva, muAtripla), etravirine (Intelence), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), uye saquinavir (Invirase); modafinil (Provigil); nafcillin; nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); rifampin (Rifamate, Rifater); rifapentine (Priftin); steroid mishonga yakadai seDexamethasone (Decadron); telithromycin (Ketek); uye voriconazole (Vfend). Mimwe mishonga yakawanda inogona zvakare kubatana neaxitinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St John's wort.
  • udza chiremba wako kana uine ronda risina kupora, kana iwe uine kana wakambove nezvinetso zvekubuda ropa; kugwamba kweropa; kukwirira kweropa; chirwere chemwoyo; chirwere cheshuga; cholesterol yakawanda; kubuda ropa mudumbu kana ura; kenza yeuropi; embolism embolism (ropa rinovhara mumapapu ako); sitiroko kana ministerroke (TIA); kana moyo; chiropa; kana chirwere chetachiona.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kana iwe uchironga kubereka mwana. Kana iwe uri munhukadzi, uchafanirwa kutora bvunzo yemimba usati watanga kurapwa uye shandisa mabhaisikopo kudzivirira kubata pamuviri panguva yekurapwa kwako uye kwevhiki rimwe mushure meyero yako yekupedzisira. Kana iwe uri murume, iwe neako mukadzi mukadzi iwe unofanirwa kushandisa kuberekwa panguva yekurapwa kwako uye kwevhiki rimwe mushure meyako yekupedzisira dosi. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe kana mumwe wako ukava nepamuviri paunenge uchitora axitinib, danaidza chiremba wako. Axitinib inogona kukuvadza fetus.
  • udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa panguva yekurapa kwako neaxitinib uye kwemavhiki maviri mushure mekupedzisira kwako.
  • iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi. Taura nachiremba wako nezve njodzi dzekutora axitinib.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora axitinib. Chiremba wako anokuudza kuti usiye kutora axitinib mazuva maviri usati wavhiyiwa uye kana zvichinge zvakachengeteka kuti iwe utange kutora axitinib zvakare mushure mekuvhiyiwa kwako.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.


Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Kana iwe ukarasikirwa neiyo muyero weaxitinib, ruka iro dosi uye utore yako inotevera dosi panguva yakajairwa nguva. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Axitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • manyoka
  • kuderera mukuda kudya kana kugona kuravira zvinhu
  • kuonda
  • kusvotwa
  • kurutsa
  • kuvimbiswa
  • kuneta
  • kushaya simba
  • chinja inzwi rezwi rako
  • kutsvuka, kurwadziwa, chiveve, kugwinha, kana kuchenesa kana kupenya kweganda pamaoko ako netsoka
  • kukosora
  • kubatana kana kurwadziwa kwemhasuru
  • maronda emuromo
  • kurwadziwa nemudumbu
  • kupisa moyo
  • musoro
  • dzungu
  • mapundu
  • kuvava
  • ganda rakaoma
  • kunzwa kupisa kana kutonhora
  • ganda rakachenuruka
  • kukurumidza moyo kurova
  • kurasikirwa nevhudzi
  • kurira munzeve
  • nyota
  • Mamota
  • ronda kana kucheka zvisingarape

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana rubatsiro rwekukurumidzira rwekurapa:

  • kurwadziwa kwakanyanya mudumbu
  • mweya wekufema
  • kuzvimba maoko kana tsoka
  • kubuda ropa zvisina kujairika kana kupwanya
  • nhema uye yekumhara zvituru
  • ropa dzvuku muzvituru
  • kurutsa kweropa
  • kurutsa zvinhu zvinoita kunge kofi nzvimbo
  • kurwadziwa pachipfuva kana kumanikidza
  • kurwadziwa mumaoko, musana, mutsipa, kana shaya
  • kuzvimba, unyoro, kudziya, kana kutsvuka kwegumbo
  • kamwe kamwe kupera kana kushaya simba kwechiso, ruoko, kana gumbo (kunyanya kune rumwe rutivi rwemuviri)
  • kukanganiswa kwepakarepo, kunetseka kutaura kana kunzwisisa
  • pakarepo dambudziko rekuona mune rimwe kana maviri maziso
  • kamwe-kamwe kunetseka kufamba, dzungu, kurasikirwa kwechiyero kana kubatana
  • kamwe kamwe kwakakomba musoro uye pasina chikonzero chinozivikanwa
  • pfari
  • kurasikirwa kwemaonero

Axitinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.


Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo pamhepo pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • dzungu
  • pfari
  • kukosora ropa

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari kuti aongorore mhinduro yemuviri wako kuaxitinib. Chiremba wako anozoongorora zvekare kuwedzerwa kweropa rako panguva yekurapwa kwako neaxitinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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Yekupedzisira Yakagadziridzwa - 08/15/2020

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