Tofacitinib

Zvemukati

• Usati watora tofacitinib,
• Tofacitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Kutora tofacitinib kunogona kudzikisira kugona kwako kurwisa hutachiona uye kuwedzera njodzi yekuti uchawana hutachiona hwakakomba, kusanganisira zvakanyanya fungal, bhakitiriya, kana hutachiona hutachiona hunopararira nemuviri. Zvirwere izvi zvingangoda kurapwa muchipatara uye zvinogona kukonzera kufa. Udza chiremba wako kana iwe uchiwanzo kuwana chero hutachiona hutachiona kana kana iwe uchifunga kuti ungave uine chero hutachiona hutachiona izvozvi. Izvi zvinosanganisira hutachiona hushoma (sekucheka kana maronda akavhurika), hutachiona hunouya nekuenda (senge maronda anotonhora), uye hutachiona husingaperi husingaendi. Uyezve udza chiremba wako kana iwe kana wakambove nechirwere cheshuga, hutachiona hwehutachiona hwehutachiona (HIV), wakawana immunodeficiency syndrome (AIDS), chirwere chemapapu, kana chero imwe mamiriro ezvinhu anokanganisa immune system yako. Iwe unofanirwa zvakare kuudza chiremba wako kana iwe uchigara kana kuti wakambogara munzvimbo dzakadai seOhio kana Mississippi rwizi rwizi uko kwakanyanya hutachiona hutachiona hwakawanda. Kumbira chiremba wako kana iwe usina chokwadi kana hutachiona uhwu hwakajairika munharaunda yako. Udza chiremba wako kana uri kutora mishonga inoderedza mashandiro ezvirwere zvemuviri seizvi zvinotevera: abatacept (Orencia); adalimumab (Humira); anakinra (Kineret); azathioprine (Azasan, Imuran); certolizumab (Cimzia); cyclosporine (Gengraf, Neoral, Sandimmune); etanercept (Enbrel); golimumab (Simponi); infliximab (Remicade); methotrexate (Otrexup, Rasuvo, Trexall); rituximab (Rituxan); steroids inosanganisira dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), uye prednisone (Rayos); tacrolimus (Astagraf, Envarsus XR, Prograf); uye tocilizumab (Actemra).

Chiremba wako anokucherechedza iwe nezviratidzo zvehutachiona panguva uye mushure mekurapa kwako. Kana iwe uine chero cheanotevera zviratidzo usati watanga kurapwa kwako kana kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchirapwa, dana chiremba wako nekukasira: fever; vangadikitira; chills; tsandanyama aches; kumedza kunorwadza kana kunetsa; kukosora; mweya wekufema; kuonda; inodziya, tsvuku, kana inorwadza ganda; mapundu anorwadza; kurwadziwa nemusoro, kunzwisisika kuchiedza, kuomesa kwemutsipa, kuvhiringidzika; kazhinji, kunorwadza, kana kutsva kwekunzwa panguva yekuita weti; kurwadziwa mudumbu; manyoka; kana kuneta zvakanyanya.

Unogona kunge uine hutachiona (TB; chirwere chakakomba chemapapu) asi usina zviratidzo zvechirwere. Muchiitiko ichi, kushandisa tofacitinib kunogona kuita kuti hutachiona hwako huwedzere uye huite kuti iwe uve nezviratidzo. Chiremba wako achaita ongororo yeganda kuti aone kana uine hutachiona hweTB husinga shande usati watanga kurapwa kwako ne tofacitinib. Kana zvichidikanwa, chiremba wako achakupa mishonga yekurapa hutachiona usati watanga kushandisa tofacitinib. Udza chiremba wako kana wakambove neTB kana kuti wakambove neTB, kana wakambogara kana kushanyira nyika ine TB yakajairika, kana kuti kana wakambove pedyo nemunhu ane TB. Kana iwe uine chero cheanotevera zviratidzo zveTB, kana kana iwe ukaita chero eapi eaya maratidziro panguva yekurapwa kwako, fonera chiremba wako nekukasika: kukosora, kukosora mamota ane ropa, kuonda, kurasikirwa kwemhasuru toni, kana fivha.

Kutora tofacitinib muhombe pane yakadomwa doses kunogona kukonzera zvakakomba kana kutyisidzira hupenyu matambudziko emwoyo panguva yekurapa kwako. Udza chiremba wako kana iwe uine makore makumi mashanu ekuberekwa kana kupfuura kana iwe uchisvuta, uye kana uine cholesterol yakawanda, BP, kana chirwere cheshuga. Tora tofacitinib chaizvo sezvakarairwa. Usatore zvimwe zvacho kana kuitora kakawanda kupfuura zvakatemwa nachiremba wako.

Kutora tofacitinib kunogona kuwedzera njodzi yekuti uchaita lymphoma (kenza inotanga mumasero eropa anorwisa hutachiona) kana mamwe marudzi ekenza, kusanganisira cancer yeganda. Vamwe vanhu vakatora tofacitinib nemimwe mishonga mushure mekunge vaiswa itsvo vakagadzira mamiriro akaita kuti miviri yavo ibudise masero machena eropa akawandisa. Udza chiremba wako kana iwe wakambove kana chero rudzi rwekenza kana wakamboiswa itsvo.

Kutora tofacitinib muhombe pane yakadomwa doses kunogona kuwedzera njodzi yekutyisidzira hupenyu ropa. Udza chiremba wako kana iwe uine makore makumi mashanu ekuberekwa kana kupfuura uye uri panjodzi yemwoyo kana chirwere chemutsipa weropa. Zvakare, udza chiremba wako kana iwe wakambove neropa rakavhara mumakumbo ako, maoko, kana mapapu, kana mune tsinga. Tora tofacitinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge waita .

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa netofacitinib uye nguva yega yega paunozadza tsamba yako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Tofacitinib inoshandiswa yoga kana nemimwe mishonga kurapa rheumatoid arthritis (mamiriro umo muviri unorwisa majoini ayo achikonzera kurwadziwa, kuzvimba, uye kurasikirwa nebasa) muvanhu vasina kupindura methotrexate (Otrexup, Rasuvo, Trexall). Inoshandiswa zvakare pamwe ne methotrexate, sulfasalazine (Azulfidine), kana leflunomide (Arava) kurapa psoriatic arthritis (mamiriro anokonzera kurwadza kwemajoini uye kuzvimba uye zviyero paganda) mune vanhu vasina kupindura iyi mishonga chete. Tofacitinib inoshandiswa kurapa ulcerative colitis (chirwere chinokonzeresa kuzvimba uye maronda mumutsara wekoloni [ura hukuru] uye rectum) mune vanhu vasingakwanise kutora kana vasina kupindura kune tumor necrosis factor (TNF) inhibitor mishonga. Iyo zvakare inoshandiswa kurapa polyarticular yevana vechidiki idiopathic arthritis (PJIA; mhando yehudiki arthritis iyo inobata mashanu kana anopfuura majoini mukati memwedzi mitanhatu yekutanga yemamiriro acho, zvichikonzera kurwadziwa, kuzvimba, uye kurasikirwa kwebasa) muvana makore maviri zvichikwira. Tofacitinib iri mukirasi yemishonga inonzi Janus kinase (JAK) inhibitors. Inoshanda nekuderedza mashandiro e immune immune.

Tofacitinib inouya sehwendefa, yakawedzera-kuburitsa (yakareba-inoshanda) piritsi, uye semhinduro yemuromo (mvura) kutora nemuromo. Nekurapa ulcerative colitis, rheumatoid arthritis, kana psoriatic arthritis, iyo piritsi inowanzo kutorwa kaviri zuva nezuva kana kana pasina chikafu uye iyo yakawedzerwa-kuburitsa piritsi inowanzo kutorwa kamwe zuva nezuva ne kana pasina chikafu. Nekurapa kwe polyarticular kosi yevechidiki idiopathic arthritis, piritsi kana mhinduro yemumuromo inowanzo kutorwa kaviri zuva nezuva ne kana pasina chikafu. Tora tofacitinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora tofacitinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mahwendefa akasunungurwa-akazara; usatsemure, kutsenga, kana kuvapwanya.

Gara uchishandisa syringe yemumuromo inouya netofacitinib mhinduro kuyera dosi yako. Taura nachiremba wako kana wemishonga kana iwe uine mibvunzo nezve maitiro ekuyera muyero wako we tofacitinib solution.

Kana iwe kana mwana wako muchitora tofacitinib mhinduro yemumuromo, bvunza wako wemishonga kana chiremba kopi yemirairo yekugadzira yekushandisa. Ngwarira kuverenga iyi mirairo.

Chiremba wako angangoda kudzikisa dosi yako kana kumisa kurapwa kwako kana iwe ukawana mamwe akanyanya mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti unonzwa sei panguva yekurapwa kwako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora tofacitinib,

• udza chiremba wako uye wemishonga kana uri weergoria kune tofacitinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumatafura e tofacitinib, akawedzeredzwa mapiritsi ekuburitsa, kana mhinduro yemumuromo. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa muchikamu CHINOKOSHA CHENYENZO uye chero ipi inotevera: mimwe mishonga inodzivirira fungal yakadai se fluconazole (Diflucan), itraconazole (Onmel, Sporanox), uye ketoconazole; asipurini uye mamwe nonsteroidal anti-anogumbura mishonga (NSAIDs) senge ibuprofen (Advil, Motrin) uye naproxen (Naprosyn, Aleve); carbamazepine (Carbatrol, Tegretol, Equetro, nevamwe); clarithromycin (Biaxin, muPrevpac); mimwe mishonga yeHIV inosanganisira indinavir (Crixivan), nelfinavir (Viracept), uye ritonavir (Norvir, muKaletra); nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); uye rifampin (Rifadin, Rimactane, muRifamate, muRifater). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe uine kurwadziwa kwemudumbu uko kusati kwaonekwa uye kana iwe uine kana wakambove nemaronda (maronda ari mukati memudumbu mako kana ura), diverticulitis (kuzvimba kwemukati mematumbo makuru), chirwere chechiropa kusanganisira hepatitis B kana hepatitis C, cancer, anemia (yakaderera pane yakajairwa nhamba yemasero matsvuku eropa), dialysis (kurapwa kwekuchenesa ropa kana itsvo dzisingashande mushe), kana chirwere cheitsvo. Kana iwe uri kutora akawedzera-kuburitsa mapiritsi, udza chiremba wako kana iwe uine kuderera kana kuvharika kweako ako ekugaya system.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe haufanire kuve nepamuviri iwe paunenge uchitora tofacitinib. Kana iwe ukava nepamuviri uchitora tofacitinib, danaidza chiremba wako.
• udza chiremba wako kana iwe uchiyamwisa. Usamwisa mwana paunenge uchinwa mapiritsi etofacitinib kana mhinduro yemumuromo uye kwemaawa angangoita gumi nemasere mushure mekupedzisira kwehwendefa repiritsi kana kwemaawa makumi matatu nemasere mushure mekupedzisira kwehwendefa rekuburitsa.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvakadzi. Taura nachiremba wako nezve njodzi dzekutora tofacitinib.
• udza chiremba wako kana iwe uchangobva kugamuchira kana kuti wakarongerwa kupihwa chero majekiseni. Kana iwe uchida chero majekiseni, iwe ungatofanira kugamuchira majekiseni uye womirira imwe nguva usati watanga kurapwa kwako ne tofacitinib. Hauna majekiseni panguva yekurapa kwako pasina kutaura nachiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Tofacitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• musoro
• yakakora kana inomhanya mhino

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• mikoko, kuzvimba kwechiso, maziso, miromo, kana huro, kunetseka kumedza kana kufema
• kurwadziwa mudumbu, kunyanya kana kukauya nefivha uye manyoka kana kupatirwa
• yero yeganda kana maziso
• kurasikirwa nenzara
• weti yakasviba
• ivhu-rakapetana ura kufamba
• kurutsa
• mapundu
• ganda rakachenuruka
• mweya wekufema

Tofacitinib inogona kukonzera kuwedzera kweropa rako remafuta akawandisa. Chiremba wako acharaira bvunzo kuti atarise cholesterol yako panguva yekurapa kwako ne tofacitinib. Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.

Tofacitinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Rasa chero mhinduro isina kushandiswa mazuva makumi matanhatu mushure mekuvhura bhodhoro.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune tofacitinib.

Kana iwe uri kutora akawedzeredzwa-kuburitsa mapiritsi iwe unogona kuona chimwe chinhu chinotaridzika kunge piritsi mune yako ura kufamba. Iyi ingori hwendefa risina chinhu, uye izvi hazvireve kuti hauna kuwana yako yakazara mushonga.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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