Ponatinib

Zvemukati

• Usati watora ponatinib,
• Ponatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, rega kutora ponatinib uye udane chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Ponatinib inogona kukonzeresa kana kutyisidzira hupenyu kuvhara ropa mumakumbo ako kana mapapu, kurwiswa kwemoyo, kana kurohwa. Udza chiremba wako kana iwe kana wakambove neropa rakavhara mumapapu ako kana makumbo; sitiroko; kukwirira kweropa; hyperlipidemia (yakakwira cholesterol mumuropa rako); inononoka, inokurumidza, kana isina kujairika kurova kwemoyo; peripheral vascular chirwere (kudzikira kwemitsipa yeropa mutsoka, makumbo, kana maoko zvichikonzeresa chiveve, kurwadziwa, kana kutonhora muchikamu icho chemuviri) chirwere chemwoyo; kana chirwere chemwoyo. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza: kurwadziwa kwepfupa; mweya wekufema; dzungu kana kupera simba; kungoerekana wavhiringidzika kana kunetseka kutaura kana kunzwisisa; kamwe kamwe kupera kana kushaya simba kwechiso, ruoko, kana gumbo kune rumwe rutivi rwemuviri; pakarepo musoro wakakomba; gumbo, ruoko, musana, mutsipa, kana kurwadziwa kweshaya; kunzwa kwekudziya mugumbo repasi; kana kuzvimba kwetsoka, makumbo, kana makumbo ezasi.

Ponatinib inogona kukonzeresa kana kutyisidzira hupenyu kukundikana kwemoyo (mamiriro umo moyo usingakwanise kupomba ropa rakakwana kune mamwe mativi emuviri) uye arrhythmias (isina kujairika moyo mutinhimira). Udza chiremba wako kana iwe kana wakambove nematambudziko emoyo, kusanganisira kutadza kwemoyo, QT kuwedzerwa (irregular moyo rhythm iyo inogona kutungamira mukufenda, kurasikirwa kwekuziva, kubatwa, kana kufa kamwe kamwe); kana kurova kwehana kunononoka, nekukurumidza, kana kusingaite. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza: kupfupika kwemweya wekufema; kurwadziwa muchipfuva; nekukurumidza, zvisina kujairika, kana kurova kurova kwemoyo; dzungu; kana kufenda.

Ponatinib inogona kukanganisa zvakakomba kana kutyisidzira hupenyu kuchiropa. Udza chiremba wako kana iwe wakambove kana wakambove nechirwere chechiropa kana matambudziko nechiropa chako. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, danaidza chiremba wako nekukasira: kuchenesa, maziso eyero kana ganda, weti yakasviba, kana kurwadziwa kana kusagadzikana mune yekurudyi kumusoro mudumbu nzvimbo.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mimwe bvunzo usati watanga uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune ponatinib.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa neponatinib uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Ponatinib inoshandiswa kurapa mamwe marudzi echirwere chisingaperi che myeloid leukemia (CML; rudzi rwekenza yemasero machena eropa), kusanganisira kurapwa kune vanhu vasingachagone kubatsirwa nemamwe mishonga yeCML kana vasingakwanise kutora mishonga iyi nekuda kwemhedzisiro. Ponatinib inoshandiswawo kurapa mamwe marudzi eacute lymphoblastic leukemia (ZVESE; rudzi rwekenza yemasero machena eropa) mune vanhu vasingachagone kubatsirwa kubva kumimwe mishonga yeleukemia kana vasingakwanise kutora mishonga iyi nekuda kwemhedzisiro. Ponatinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kupararira kwekenza masero.

Ponatinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva kana pasina chikafu. Tora ponatinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora ponatinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Chiremba wako angangoda kunonoka kurapwa kwako, gadzirisa dosi yako, kana kumisa zvachose kurapwa kwako kweponatinib zvichienderana nemhinduro yako pakurapwa uye chero mhedzisiro iwe yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora ponatinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora ponatinib usina kutaura nachiremba wako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora ponatinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune ponatinib, chero mimwe mishonga, lactose, kana chero chipi zvacho chemapiritsi eponatinib. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: ketoconazole (Nizoral); mishonga yekudzikisa mudumbu acid, senge lansoprazole (Prevacid); uye rifampin (Rifadin, Rimactane, muRifamate, muRifater). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana neponatinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana iwe kana wakambove nechinetso chekubuda ropa; chirwere cheshuga; pancreatitis (kuzvimba kwepancreas, gland kuseri kwedumbu iro rinogadzira zvinhu zvekubatsira kugaya); kana kana iwe uri lactose isingashiviriri (kutadza kugaya zvigadzirwa zvemukaka). Uyezve, udza chiremba wako kana iwe uchinwa kana kuti wakambonwa doro rakawanda.
• iwe unofanirwa kuziva kuti ponatinib inogona kudzora kubereka muvakadzi. Nekudaro, iwe haufanire kufunga kuti iwe kana mumwe wako haugone kuve nepamuviri. Udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Kana iwe uri munhukadzi, iwe unozofanirwa kutora kutora nhumbu usati watanga kurapwa. Iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako neponatinib uye kwemavhiki matatu mushure mekumira kutora mushonga. Taura nachiremba wako nezvemhando dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora ponatinib, dana chiremba wako nekukurumidza. Ponatinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchi tora ponatinib uye kwemazuva matanhatu mushure mekupedzisira dosi.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora ponatinib. Kana iwe wakarongerwa kuvhiyiwa, chiremba wako anokuudza iwe kuti urege kutora ponatinib kwemazuva anosvika manomwe usati wavhiyiwa kana maitiro. Chiremba wako anokuudza iwe nguva yekutanga kutora ponatinib zvakare mushure mekuvhiyiwa kwako.
• iwe unofanirwa kuziva kuti yako yeropa inogona kuwedzera panguva yekurapa kwako neponatinib. Chiremba wako angangotarisa yako yeropa panguva yekurapa kwako.

Usadye huwandu hwakawanda hwemuzambiringa kana kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Ponatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• mapundu
• ganda rakaoma
• manyoka
• kuvimbiswa
• kurasikirwa nevhudzi
• zvigamba zvichena kana maronda pamuromo kana mumuromo nehuro
• kurasikirwa nenzara
• kuonda
• kukosora
• kunetseka kurara kana kuramba wakarara
• musana, bone, kubatana, nhengo, kana kurwadziwa kwemhasuru

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, rega kutora ponatinib uye udane chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kupwanya kusingawanzo kana kubuda ropa
• Ropa kana dema, zvigaro zvekugara
• ropa mumurini
• kurutsa kweropa
• kubuda kweropa zvisina kujairika kana kunorema kupfuura kubuda kumwedzi kubuda ropa
• rutsa zvinoita kunge kofi nzvimbo
• kazhinji mhino dzinobuda ropa
• kukosora ropa
• yakaoma, tsvuku, inorwadza, kana kutsamwa maziso
• kunzwisisika kuchiedza
• kuona kwakakanganiswa, mafashama, kuona zvakapetwa, kana kumwe kuchinja kwemaonero
• maronda asingarape
• fivha, huro, chironda, kana zvimwe zviratidzo zvehutachiona
• shanduko mukuravira; kushaya simba kwemhasuru; kudonhedza maziso kana chikamu chechiso; kurira, kupisa, kurwadziwa, kana kurasikirwa kwekunzwa mumaoko kana mutsoka
• kurwadziwa nemusoro, kubatwa, kusagadzikana, matambudziko kufunga, kana shanduko kana kurasikirwa kwemaonero
• kuderera kwekuita weti
• kuneta zvakanyanya kana kushaya simba
• kurema kuwedzera
• kuzvimba kwechiso chako, maoko, tsoka, makumbo, kana makumbo ezasi
• kurwadziwa, kuzvimba, kana unyoro mudumbu (mudumbu nzvimbo)
• kusvotwa
• kurutsa
• kurwadziwa kunoenderera kunotanga munzvimbo yemudumbu asi kunogona kupararira kumashure

Ponatinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• fivha, huro, chironda, uye zvimwe zviratidzo zvehutachiona
• inokurumidza, isina kujairika, kana kurova kurova kwemoyo
• kuneta
• kurwadziwa pachipfuva

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Iclusig^®