Dabrafenib

Zvemukati

• Usati watora dabrafenib,
• Dabrafenib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi fonera chiremba wako nekukasira:

Dabrafenib inoshandiswa yoga kana musanganiswa ne trametinib (Mekinist) kurapa mamwe marudzi e melanoma (rudzi rwegomarara reganda) risingakwanise kurapwa nekuvhiya kana rakapararira kune dzimwe nhengo dzemuviri. Iyo inoshandiswa zvakare pamwe ne trametinib yekurapa uye kudzivirira kudzoka kweimwe mhando yemelanoma mushure mekuvhiyiwa kuti ibvise iyo uye chero anokanganisa lymph node. Dabrafenib inoshandiswawo pamwe chete ne trametinib kurapa imwe mhando yekenza isiri-diki kenza yemapapu kenza (NSCLC) iyo yakapararira kumatunhu ari pedyo kana kune zvimwe zvikamu zvemuviri. Iyo inoshandiswa zvakare kurapa imwe mhando yekenza yehutachiona iyo yakapararira kumatishu ari pedyo kana kune zvimwe zvikamu zvemuviri izvo zvisina kupindura kurapwa kwekare (s). Dabrafenib ari mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kupararira kwekenza masero.

Dabrafenib inouya sekapuleti kutora nemuromo. Inowanzo kutorwa kaviri pazuva pane isina chinhu mudumbu, 1 awa pamberi kana maviri maawa mushure mekudya. Tora dabrafenib anenge maawa gumi nemaviri akaparadzaniswa panguva dzakatenderedza nguva dzakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora dabrafenib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako. Usarega kutora dabrafenib usina kutaura nachiremba wako.

Medza macapsules akazara; usavhure, kana kuvhuna, kana kuvapwanya.

Chiremba wako anogona kugadzirisa dhizaini yako kana kwechinguva kana zvachose kumisa kurapwa kwako zvichienderana nemhinduro yako pakurapwa uye chero mhedzisiro iwe yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro Rekurapa) paunotanga kurapwa nedabrafenib uye nguva yega yega paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora dabrafenib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune dabrafenib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mune dabrafenib capsules. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero cheanotevera: clarithromycin (Biaxin, muPrevPac); dexamethasone; gemfibrozil (Lopid); ketoconazole; midazolam; nefazodone; rifampin (Rifadin, muRifamate, muRifater, Rimactane); uye warfarin (Coumadin, Jantoven). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana ne dabrafenib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana iwe kana wakambove nechirwere cheshuga; glucose-6-phosphate dehydrogenase (G6PD) kushomeka (chibereko). matambudziko ekubuda ropa; matambudziko eziso; kutadza kwemoyo kana mamwe matambudziko emoyo; chiropa kana itsvo chirwere; kana chero imwe mamiriro ekurapa.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri, kana kana iwe uronga kuronga kuva nemwana. Kana iwe uri munhukadzi, iwe uchafanirwa kuve nemimba yekubata usati watanga kurapwa, uye iwe unofanirwa kushandisa inoshanda kubereka kudzivirira kudzivirira kubata pamuviri panguva yekurapwa kwako uye kwemavhiki maviri mushure medosi yako yekupedzisira. Kana iwe uri murume uye mumwe wako achigona kuve nepamuviri, iwe unofanirwa kushandisa kondomu paunenge uchinwa mushonga uyu, uye kwemavhiki maviri mushure mekurapwa kwako, kunyangwe iwe uine vasectomy (kuvhiyiwa kudzivirira urume kubva mumuviri wako uye zvichikonzera kubata) . Iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi; zvisinei, haufanire kufunga kuti haugone kubata pamuviri kana kuti haugone kuitisa mumwe munhu nhumbu. Kana iwe kana mumwe wako ukava nepamuviri uchitora dabrafenib, danaidza chiremba wako. Dabrafenib inogona kukuvadza fetus.
• iwe unofanirwa kuziva kuti dabrafenib inogona kudzikisira kushanda kwemahomoni ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, mapiritsi, uye majekiseni). Iwe unofanirwa kushandisa imwe nzira yekudzivirira kuberekwa kudzivirira nhumbu mukati mako kana mumwe wako panguva yekurapwa kwako ne dabrafenib uye kwemavhiki maviri mushure mekupedzisira dosi. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira.
• udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchi tora dabrafenib uye kwemavhiki maviri mushure mekupedzisira dosi.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora dabrafenib.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana iri isingasviki maawa matanhatu kusvika yako inotevera yakarongwa dhizaini, ruka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Dabrafenib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• kubatana, mhasuru, kana kurwadziwa musana
• kusvotwa
• manyoka
• kuvimbiswa
• kurasikirwa nenzara
• kukosora, kubuda mvura, kana kurwadziwa pahuro
• kurasikirwa nevhudzi
• kuneta

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi fonera chiremba wako nekukasira:

• shanduko paganda (nyowani nyowani, ganda rinorwadza, kana bhuru tsvuku inobuda ropa kana isingarape)
• chinja saizi kana ruvara rwema mole
• mapundu, ganda dzvuku, kana mapundu
• kupindwa nechando
• kufenda
• dzungu, hurema, kana kushaya simba
• chills
• kuderera kwekuita weti
• kuzvimba kwemaoko, tsoka, makumbo, kana makumbo ezasi
• kugara uchiita weti
• kuwedzera nyota
• kurwadziwa kweziso
• matsvuku kana kuzvimba maziso
• kunzwisisika kuchiedza
• kuona kwakakanganiswa kana kuchinja kwemaonero, kusanganisira kuona halos (rondedzero yakakomberedza zvakapoteredza zvinhu) kana mavara ane mavara
• kuzvimba, kurwadziwa, kutsvuka, kana kubvaruka kweganda pazvanza uye pasi petsoka
• kurwadziwa kunoenderera kunotanga munzvimbo yemudumbu asi kunogona kupararira kumashure
• kubuda ropa zvisina kujairika kana kupwanya
• Ropa kana dema, zvigaro zvekugara
• kukosora kana kurutsa ropa kana zvinhu zvinoita kunge kofi nzvimbo
• kurwadziwa pachipfuva
• mweya wekufema
• kuzvimba kwemaoko, tsoka, makumbo kana makumbo ezasi
• nekukurumidza, zvisina kujairika, kana kurova kurova kwemoyo
• yero yeganda nemaziso

Dabrafenib inogona kuwedzera njodzi yekuti iwe uchava nekenza nyowani yeganda kana imwe kanzira. Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.

Dabrafenib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa ne dabrafenib. Chiremba wako acharaira mamwe marabhoritari ekuongorora usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune dabrafenib. Chiremba wako anozotarisa ganda rako kuti paine shanduko here zvisati zvaitika, mwedzi miviri yega panguva yekurapwa kwako, uye kusvika pamwedzi mitanhatu mushure mekurapwa.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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