Munyori: Marcus Baldwin
Zuva Rekusika: 20 Chikumi 2021
Gadziridza Zuva: 16 Mbudzi 2024
Anonim
Dolutegravir: Pros and Cons (Are There Any Cons?)
Vhidhiyo: Dolutegravir: Pros and Cons (Are There Any Cons?)

Zvemukati

Dolutegravir inoshandiswa nemimwe mishonga yekurapa hutachiona hwehutachiona hwehutachiona hwehutachiona muhutachiona muvanhu vakuru nevana vana masvondo mana ekuberekwa uye vanorema anosvika 6.6 lbs (3 kg). Inoshandiswa zvakare pamwe chete ne rilpivirine (Edurant) kurapa HIV mune vamwe vanhu vakuru kutsiva yavo yazvino mishonga yeHIV (s) yakatorwa kwemwedzi mitanhatu. Dolutegravir iri mukirasi yemishonga inonzi HIV integrase inhibitors. Inoshanda nekuderedza huwandu hweHIV muropa rako uye nekuwedzera huwandu hwema immune maseru ayo anobatsira kurwisa hutachiona mumuviri wako. Kunyangwe dolutegravir isingarape HIV, kuishandisa pamwe chete nemimwe mishonga kunogona kudzikisira mukana wako wekuwana immunodeficiency syndrome (AIDS) nezvirwere zvine chekuita neHIV senge hutachiona hwakakomba kana gomarara. Kutora mishonga iyi pamwe nekuita bonde rakachengeteka uye nekuita mamwe mararamire shanduko kunogona kudzora njodzi yekutapurirana (kuparadzira) hutachiona hweHIV kune vamwe vanhu.

Dolutegravir inouya sehwendefa uye sehwendefa rekumisa (piritsi yekunyunguduka mune mvura) kutora nemuromo. Inowanzotorwa kamwe kana kaviri pazuva kana kana pasina chikafu. Tora dolutegravir kwakatenderedza nguva imwechete (ma) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora dolutegravir chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Usatsvage, kucheka, kana kupwanya mapiritsi ekumiswa kwemuromo. Iwe unogona kumedza iyo piritsi yakazara, imwe panguva, kana kuvasanganisa nemvura yekunwa usati washandisa.

Kana iwe ukasanganisa mapiritsi ekumiswa pamuromo mumvura yekunwa, wedzera iyo yakatemwa nhamba yehwendefa (s) kune iyo dosing kapu. Kana uchitora 1 kana 3 piritsi (s) yekumisa pamuromo, wedzera 1 teaspoon (5 mL) yemvura yekunwa mukapu. Kana ukatora mapiritsi mana, mashanu, kana matanhatu ekumiswa kwemuromo, wedzera mashupuni maviri (10 mL) emvura yekunwa mukapu. Usashandise chero imwe mvura kunyungudutsa piritsi. Shandura mukombe kwemaminetsi 1 kana maviri kana kusvika musanganiswa wanyungudika zvachose; musanganiswa uchaonekwa makore. Kana hwendefa (hw) hwekumisa hwanyungudika zvachose, inwa musanganiswa uchangosanganisa. Kana yave neinopfuura maminitsi makumi matatu musanganisa musanganiswa, rasa musanganiswa.

Kana uchipa mapiritsi ekumisa musanganiswa kumwana, ita shuwa kuti akatwasuka paanotora. Kana paine musanganiswa wakasara mumukombe, wedzera imwe 1 teaspoon (5 mL) yemvura yekunwa mukapu, svetuka, uye upe iyo yese kumwana kuti ave nechokwadi chekuti mwana anowana muyero wakazara.


Kana uchipa mapiritsi emusanganiswa wekumisa kumucheche, shandisa sirinji yemuromo yakapihwa kuyera uye kupa muyero. Isa muromo wesirinji mumukombe weiyo dosing pamwe nemusanganiswa wakagadzirwa kuti uukweze mukati mejekiseni. Isa muromo wesirinji yemuromo mumuromo wemwana uchipesana nechomukati padama. Zvinyoro nyorovera pasi pane plunger kuti upe iyo dosi zvishoma. Bvumira nguva yekuti mucheche amedze musanganiswa. Wedzera imwe 1 teaspoon (5 mL) yemvura yekunwa kukapu uye kutenderera.Dhirowa musanganiswa wakasara mupini uye upe iyo yese kumucheche. Dzokorora kana paine mumwe wemusanganiswa wakasara musirinji kuti uone kuti mucheche anowana muyero uzere. Iko kusanganiswa kunofanirwa kupihwa kumwana mukati memaminitsi makumi matatu yekusanganisa. Mushure mechiyero, gezai kapu uye sirinji zvikamu zvakasiyana nemvura. Rega zvikamu zviome zvachose usati waunganazve uye nekuchengetedza.

Usachinje kubva pamahwendefa kuenda kune mapiritsi (e) ekumiswa usati watanga kutaura nachiremba wako.

Ramba uchitora dolutegravir kunyangwe uchinzwa mushe. Usarega kutora dolutegravir usina kutaura nachiremba wako. Kana kupihwa kwako kwe dolutegravir kwadzikira, tora zvimwe kubva kuna chiremba wako kana wemishonga. Kana iwe ukarega kutora dolutegravir kana kupotsa dosi, mamiriro ako anogona kuve akaipisisa uye zvakanyanya kunetsa kurapa nemushonga.


Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora dolutegravir,

  • udza chiremba wako uye wemishonga kana uri weergoria kune dolutegravir, chero mimwe mishonga, kana chero chinhu chinosanganiswa mumapiritsi e dolutegravir. Kumbira mushonga wako wemishonga kana kutarisa ruzivo rwemurwere wemugadziri kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uri kutora dofetilide (Tikosyn). Chiremba wako anogona kukuudza kuti usatora dolutegravir kana iwe uri kutora mushonga uyu.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvekuwedzera zvekudya, zvauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: dalfampridine (Ampyra); mimwe mishonga yeHIV inosanganisira efavirenz (Sustiva, muAtripla), etravirine (Intelence), fosamprenavir (Lexiva) yakatorwa ne ritonavir (Norvir), nevirapine (Viramune), uye tipranavir (Aptivus) yakatorwa ne ritonavir (Norvir); mimwe mishonga yekubatwa inosanganisira carbamazepine (Carbatrol, Equetro, Tegretol), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital, uye phenytoin (Dilantin, Phenytek); metformin (Glumetza, Glucophage, Riomet); uye rifampin (Rifadin, Rimactane, muRifamate, muRifater). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • kana uri kutora antacids, laxatives, kana multivitamini ine aruminiyamu, magnesium, kana calcium; calcium zvinowedzera; iron inowedzera; sucralfate (Carafate); kana mabuffered mishonga yakadai seyakasvinwa aspirin, tora iwo maawa maviri mushure kana maawa matanhatu usati watora dolutegravir. Nekudaro, kana iwe ukatora dolutegravir nechikafu, unogona kutora izvi zvinowedzera panguva imwechete yaunotora dolutegravir.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
  • udza chiremba wako kana iwe kana wakambove nechirwere cheitsvo kana uri kugamuchira dialysis kurapwa kana chirwere chechiropa kusanganisira hepatitis B kana hepatitis C.
  • udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe unozofanirwa kutora kutora nhumbu usati watanga kurapwa. Taura nachiremba wako nezvenzira dzinoshanda dzekudzora kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Kana iwe ukava nepamuviri uchitora dolutegravir, danaidza chiremba wako nekukasira. Dolutegravir inogona kukuvadza fetus.
  • udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwa kana uine hutachiona hweHIV kana kana uri kutora dolutegravir.
  • Unofanirwa kuziva kuti paunenge uchinwa mishonga yekurapa hutachiona hweHIV, immune system yako inogona kusimba uye yotanga kurwisa zvimwe zvirwere zvaive mumuviri wako kare. Izvi zvinogona kukonzera kuti iwe uwedzere zviratidzo zveawo hutachiona. Kana uine zviratidzo zvitsva kana zvichikura mushure mekutanga kurapwa ne dolutegravir, ita chokwadi chekuudza chiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Dolutegravir inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kunetseka kurara kana kuramba wakarara
  • musoro
  • kurwadziwa nemudumbu
  • gasi
  • manyoka
  • kurema kuwedzera

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uch nahw a kana chimwe chezviratidzo izvi, kana icho chakanyorwa muZVINONYANYA ZVINONYANYA, rega kutora dolutegravir uye udane chiremba wako nekukurumidza kana kuti uwane kurapwa kwekukurumidzira:

  • mapundu
  • kupindwa nechando
  • kunzwa kurwara
  • kuneta zvakanyanya
  • mhasuru kana kurwadziwa kwemajoini
  • kuputika kana kubvisa ganda
  • mapundu kana maronda mumuromo
  • matsvuku kana kuzvimba maziso
  • kuzvimba kwemaziso, kumeso, miromo, muromo, rurimi kana huro
  • kunetseka kufema kana kumedza
  • yero yeziso kana ganda
  • weti yakasviba
  • pale dzakachenuruka
  • kusvotwa
  • kurutsa
  • kurasikirwa nenzara
  • kurwadziwa kumusoro kwepamusoro chikamu chedumbu

Dolutegravir inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Usabvise desiccant (kadiki kapaketi kane chinhu chinotora mwando kuchengetedza mushonga kuti uome) kubva mubhodhoro.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwebazi kuti atarise mhinduro yemuviri wako kune dolutegravir.

Chengetedza pombi ye dolutegravir paruoko. Usamirira kusvikira iwe wapererwa nemushonga kuti uzorodze tsamba yako.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Tivicay®
  • Tivicay® PD
  • Juluca® (semubatanidzwa chigadzirwa chine dolutegravir, rilpivirine)
Yekupedzisira Yakagadziridzwa - 08/15/2020

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