Alirocumab Jekiseni

Zvemukati

• Usati washandisa jekiseni realirocumab,
• Alirocumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi, rega kushandisa alirocumab jekiseni uye fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Alirocumab jekiseni inoshandiswa pamwe nekudya, yega kana musanganiswa nemimwe mishonga inoderedza cholesterol (HMG-CoA reductase inhibitors [statins] kana ezetimibe [Zetia, muLiptruzet, muVytorin]), kune vanhu vakuru vane mhuri heterozygous hypercholesterolemia (nhaka mamiriro umo cholesterol isingakwanise kubviswa mumuviri zvakajairika) kudzikisa huwandu hweshure-density lipoprotein (LDL) cholesterol ('yakaipa cholesterol') muropa. Alirocumab jekiseni inoshandiswa zvakare kune vanhu vakuru vane chirwere chemwoyo kudzikisira njodzi yekurohwa, kurohwa nemoyo, kana kurwadziwa kwakakomba kana kutyisidzira kwehupenyu. Alirocumab jekiseni iri mukirasi yemishonga inonzi proprotein convertase subtilisin kexin mhando 9 (PCSK9) inhibitor monoclonal antibodies. Inoshanda nekudzivirira kugadzirwa kweLDL cholesterol mumuviri nekudaro kudzikisira huwandu hwecholesterol iyo inogona kuvaka pamadziro etsinga.

Kuunganidzwa kwecholesterol pamadziro ako etsinga (maitiro anozivikanwa seatherosclerosis) anoderedza kuyerera kweropa uye, nekudaro, iyo oksijeni inopa kune wako moyo, uropi, uye zvimwe zvikamu zvemuviri wako.

Alirocumab jekiseni inouya semhinduro (mvura) mune yakasarudzwa sirinji uye yakafarirwa dosing peni yekujova subcutaneously (pasi peganda) kamwe chete pavhiki mbiri kana ina. Shandisa alirocumab jekiseni panguva dzakatenderedza nguva imwechete vhiki mbiri kana mana. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Shandisa alirocumab jekiseni chaizvo sekurairwa. Usashandise zvishoma kana zvishoma zvemushonga uyu kana kuushandisa kazhinji kana kwenguva yakareba kupfuura zvakatemwa nachiremba wako.

Mushure memasvondo mana kusvika masere ekurapa, chiremba wako anogona kuwedzera dosi rako zvichienderana nemhinduro yako kumushonga uyu.

Alirocumab jekiseni inobatsira kudzora cholesterol, asi hairape aya mamiriro. Enderera kushandisa alirocumab jekiseni kunyangwe iwe uchinzwa zvakanaka. Usarega kushandisa alirocumab jekiseni usingataure nachiremba wako.

Alirocumab jekiseni inouya mune yakasarudzika dosing peni uye yakasarudzika majekiseni ane mishonga yakakwana kune imwe dosi. Kana chiremba wako akakuudza kuti iwe unofanirwa kushandisa inopfuura imwe peni kana sirinji yedosi yako, shandisa mapeni kana majekiseni imwe mushure meimwe munzvimbo dzakasiyana dzejekiseni. Zvinotora masekondi makumi maviri kuti ubaye mushonga. Nguva dzose jekesa alirocumab mune yayo yakafarirwa dosing peni kana sirinji; usambozvisanganisa nemimwe mishonga. Rasa tsono dzakashandiswa, majekiseni, nemidziyo mumudziyo unodzivira; usazomboshandisa zvakare chinyoreso chakatemwa kana sirinji. Taura nachiremba wako kana wemabhizimusi nezve maratidziro aungaita mudziyo usingadzivirirwe.

Unogona jekiseni jekiseni realirocumab muhudyu mako, maoko ekumusoro, kana nzvimbo yedumbu, kunze kwenzvimbo ye2-inch yakatenderedza guvhu rako (dumbu bhatani) uye padyo nemuchiuno chako. Shandisa imwe nzvimbo jekiseni rega rega. Usapinze munzvimbo ine ganda rinorwadza, rakatsvuka, rakakuzvuka, rakazvimba, rakatsva nezuva, rakaoma, rinopisa, rinotapukirwa, kana kukuvadzwa munzira ipi neipi kana munzvimbo dzine mutsinga dzinoonekwa, mavanga, mapundu, kana kutwasuka.

Ngwarira kuverenga mirairo yemugadziri yekushandisa iyo inouya nemushonga. Iyi mirairo inotsanangura maitiro ekupinza jekiseni realirocumab jekiseni. Ive neshuwa yekubvunza wako wemishonga kana chiremba kana iwe uine chero mibvunzo nezve maitiro jekiseni uyu mushonga.

Bvisa sirinji yakasarudzwa kana yakatemwa dosing peni kubva mufiriji uye ibvumidze kudziya kune tembiricha yemukati kwemaminitsi makumi matatu kusvika makumi mana usati waishandisa. Usaise syringe yakasarudzika kana kunyorwa dosing peni kumashure mufiriji mushure mekunge yadziyirwa kukamuri tembiricha.

Usati washandisa jekiseni realirocumab, tarisa mhinduro mune yakasungwa sirinji kana peni padhuze. Iyo mishonga inofanirwa kuve yakajeka kune yakacheneruka yero uye isina yezvinhu zvinoyangarara. Usazungunuse sirinji yakasarudzwa kana yakatemwa dosing peni ine alirocumab jekiseni.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati washandisa jekiseni realirocumab,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune alirocumab jekiseni, chero mimwe mishonga, kana chero chemisanganiswa mualirocumab jekiseni. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove kana chero mamiriro ekurapa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri iwe uchishandisa alirocumab jekiseni, fonera chiremba wako.

Idya yakaderera-mafuta, yakaderera-cholesterol chikafu. Ive neshuwa yekutevera zvese zvekurovedza muviri uye zvekudya zvinokurudzirwa zvakaitwa nachiremba wako kana wezvekudya. Iwe unogona zvakare kushanyira iyo National Cholesterol Dzidzo Chirongwa (NCEP) webhusaiti kune rumwe ruzivo rwekudya pa: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Kana iwe ukajova alirocumab jekiseni vhiki mbiri dzese, jekisa iyo yakarasika dhizaini yealirocumab jekiseni nekukurumidza kana uchinge uchirangarira kana iri mukati memazuva manomwe echirwere chakarasika uye wotangazve yako yekutanga chirongwa. Nekudaro, kana iri yakareba kupfuura mazuva manomwe kubva pane yakashaikwa dhizaini, svetuka iyi dose, uye mirira kusvika yako inotevera inoteedzerwa dhosi.

Kana iwe ukajova alirocumab jekiseni vhiki yega yega ye4, jekisa iyo yakarasika dhizaini yealirocumab jekiseni nekukurumidza kana uchinge uchirangarira kana iri mukati memazuva manomwe echirwere chakarasika uye wotangazve yako yekutanga chirongwa. Kana kwave kureba kupfuura mazuva manomwe kubva padosi rakarasika, wobva wajova mushonga uye wotanga runyowani rwevhiki ina-vhiki zvichibva nezuva iri.

Usapinda jekiseni repiri kuti uwane dhosi rakarasika. Dana chiremba wako kana iwe uchinge warasikirwa neipi uye uine mibvunzo nezve zvekuita.

Alirocumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kutsvuka, kuchenesa, kuzvimba, kurwadziwa, kana unyoro panzvimbo yejekiseni
• flu-kunge zviratidzo, fivha, kutemwa nemusoro, kutonhora

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi, rega kushandisa alirocumab jekiseni uye fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kuvava
• mapundu
• mikoko
• kunetseka kufema kana kumedza
• kuzvimba kwechiso, huro, rurimi, miromo, uye maziso

Alirocumab jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchishandisa mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze mufiriji, asi usazviisa pachando. Alirocumab jekiseni inogona zvakare kuchengetwa mukati tembiricha yemukati kusvika makumi manomwe neshanu F (25 degrees C) mukatoni yepakutanga kusvika mazuva makumi matatu. Mushure memazuva makumi matatu, alirocumab inofanirwa kukandwa kure. Chengeta alirocumab jekiseni rakachengetedzwa kubva pachiedza mukatoni yekutanga.

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari kuti aongorore mhinduro yemuviri wako kune alirocumab jekiseni.

Usarega mumwe munhu achishandisa mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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