Burosumab-twza jekiseni

Zvemukati

• Usati washandisa jekiseni re burosumab-twza,
• Burosumab-twza jekiseni inogona kukonzeresa mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako:

Jekiseni reBurosumab-twza rinoshandiswa kurapa X-inosanganisirwa hypophosphatemia (XLH; chirwere chakagarwa nhaka uko muviri usinga chengetedze phosphorus uye inotungamira kumapfupa asina simba) muvakuru nevana vana vane makore matanhatu ekuberekwa nekure. Iyo inoshandiswawo kurapa bundu-rinokonzeresa osteomalacia (bundu rinokonzeresa kurasikirwa kwe phosphorus mumuviri inotungamira kumapfupa asina kusimba) asingakwanise kuvhiyiwa muvanhu vakuru nevana vana makore maviri ekuberekwa nepamusoro, jekiseni reBurosumab-twza riri kirasi yemishonga inonzi fibroblast kukura chinhu 23 (FGF23) inodzivirira masoja ekudzivirira chirwere. Izvo zvinoshanda nekudzivirira chiito chechimwe chinhu chechisikigo mumuviri chinokonzera zviratidzo zveXLH.

Burosumab-twza jekiseni inouya semhinduro (mvura) kujowa subcutaneously (pasi peganda) nachiremba kana mukoti. Nekurapa X-yakabatana hypophosphatemia, inowanzo jekisirwa kamwe chete kwemavhiki maviri evana vana kwemwedzi mitanhatu kusvika pamakore gumi nemanomwe ekuberekwa, uye kamwe chete pamasvondo mana evakuru. Nekurapa kwechipfuva-chakakonzera osteomalacia, muvana makore maviri kusvika gumi nemanomwe ekuberekwa, inowanzojowa kamwe chete pavhiki mbiri. Nekurapa kwechipfuva-chakakonzera osteomalacia muvanhu vakuru, inowanzojowa vhiki yega yega ye4 uye sezvo dosi ichiwedzerwa inogona kuiswa jekiseni vhiki mbiri dzese. Chiremba wako kana mukoti anozobaya mushonga mune rako repamusoro ruoko, chidya chepamusoro, magaro, kana dumbu nzvimbo, uye shandisa imwe jekiseni saiti nguva imwe neimwe.

Udza chiremba wako kana iwe uri kutora chero phosphate inowedzera kana imwe vhitamini D inowedzera secalcitriol (Rocaltrol) kana paricalcitol (Zemplar). Iwe unozofanirwa kumira kutora aya 1 vhiki usati watanga kurapwa.

Chiremba wako anogona kuwedzera dhizeti yako (kwete kanopfuura kamwe chete pamasvondo mana), kana anogona kusvetuka imwe dose, zvinoenderana nemhedzisiro yemabara ako ekuongorora.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati washandisa jekiseni re burosumab-twza,

• udza chiremba wako uye wemishonga kana uri weergoria kune burosumab-twza, chero mimwe mishonga, kana chero chinhu chinosanganiswa mu burosumab-twza jekiseni. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe uine chirwere cheitsvo. Chiremba wako anogona kukuudza kuti usashandise jekiseni re burosumab-twza.
• udza chiremba wako kana iwe kana wakambove neyakagadzikana gumbo chirwere (RLS; mamiriro anokonzeresa kusagadzikana mumakumbo uye kukurudzira kwakasimba kufambisa makumbo, kunyanya husiku uye kana wakagara kana kurara pasi).
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchigamuchira burosumab-twza jekiseni, fonera chiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Kana iwe ukarasikirwa nguva yekugamuchira dosi, ita imwe musangano nekukurumidza sezvazvinogona.

Burosumab-twza jekiseni inogona kukonzeresa mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• kurutsa
• kupindwa nechando
• kurwadziwa mumaoko, makumbo, kana musana
• kurwadziwa kwemhasuru
• kuvimbiswa
• dzungu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako:

• kutsvuka, kuputika, mikoko, kuchenesa, kuzvimba, kurwadziwa, kana kupwanya padyo kana panzvimbo iyo mishonga yakajowa
• mapundu kana mikoko
• kusagadzikana mumakumbo; kuda kwakasimba kufambisa makumbo, kunyanya husiku uye kana wakagara kana kurara pasi

Burosumab-twza jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari emiedzo usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kubrasumab-twza jekiseni.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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