Bvunza iyo Nyanzvi: Kurapa uye Kugadzirisa Chisingaperi Idiopathic Urticaria

Zvemukati

• 1. Antihistamines yarega kushanda kudzora zviratidzo zvangu. Ndedzipi dzimwe sarudzo dzangu?
• 2. Ndeapi marimu kana mafuta andinofanira kushandisa kugadzirisa iyo inogara icch kubva kuCIU?
• 3. CIU yangu ichazomboenda here?
• 4. Chii vanoziva vanoongorora nezve zvingakonzere CIU?
• 5. Pane here shanduko dzekudya dzandinofanira kuita kubata CIU yangu?
• 6. Ndeapi matipi aunazvo ekuziva zvinokonzeresa?
• 7. Ndedzipi nzira dzekurapa dzepamusoro dzandinogona kuedza?
• 8. Ndeapi marapirwo anogona kupihwa nachiremba wangu?

1. Antihistamines yarega kushanda kudzora zviratidzo zvangu. Ndedzipi dzimwe sarudzo dzangu?

Ndisati ndasiya ma antihistamine, ini ndinogara ndichive nechokwadi chekuti varwere vangu vari kuwedzera madosi avo. Zvakachengeteka kutora kanokwana kana zuva rinokurudzirwa zuva nezuva reasina-anti-antihistamine. Mienzaniso inosanganisira loratadine, cetirizine, fexofenadine, kana levocetirizine.

Kana yakakwira-dosi, isina-sedating antihistamines ikakundikana, anotevera matanho anosanganisira sedating antihistamines senge hydroxyzine uye doxepin. Kana, isu tichaedza H2 blockers, senge ranitidine uye famotidine, uye leukotriene inhibitors senge zileuton.

Kune mikoko yakaoma-kurapa, ndinowanzo enda kumushonga unobaya jekiseni unonzi omalizumab. Iyo ine bhenefiti yekusave steroidal uye inoshanda zvakanyanya muvazhinji varwere.

Chisingaperi idiopathic urticaria (CIU) chirwere chinodzvinyirira immune. Saka, muzviitiko zvakanyanya, ndinogona kushandisa systemic immunosuppressants senge cyclosporine.

2. Ndeapi marimu kana mafuta andinofanira kushandisa kugadzirisa iyo inogara icch kubva kuCIU?

Iyo itch kubva kuCIU inokonzerwa neyemukati histamine kuburitswa. Mhedzisiro vamiririri - kusanganisira epamusoro antihistamines - zvinonyanya kushanda pakubata zviratidzo.

Tora mvura inodziya nguva zhinji wozora mafuta anonyevenutsa uye anotonhorera kana mikoko yaputika uye painonyangadza. A topical steroid inogona zvakare kubatsira. Nekudaro, emuromo antihistamines uye omalizumab kana mamwe ma immune-system modifiers achapa kurerukirwa kwakanyanya.

3. CIU yangu ichazomboenda here?

Ehe, angangoita ese zviitiko zvechisingaperi idiopathic urticaria pakupedzisira kugadzirisa. Zvisinei, hazvigoneke kufanotaura kuti izvi zvichaitika riini.

Kuomarara kweCIU kunochinjawo nekufamba kwenguva, uye ungangoda akasiyana mazinga erapi panguva dzakasiyana. Iko kune zvakare kunogara kune njodzi yeCIU kudzoka kana ichinge yapinda mukuregererwa.

4. Chii vanoziva vanoongorora nezve zvingakonzere CIU?

Kune akati wandei mazano pakati pevaongorori nezve chinokonzeresa CIU. Pfungwa yakanyanya kuwanda ndeyekuti CIU ndeye autoimmune-senge mamiriro.

Mune vanhu vane CIU, isu tinowanzoona autoantibodies inotungamirwa kumasero anoburitsa histamine (mast masero uye basophils). Uyezve, vanhu ava vanowanzove nehumwe autoimmune kusagadzikana senge chirwere chetachiona.

Imwe dzidziso ndeyekuti kune vamiririri chaivo muserum kana plasma yevanhu vane CIU. Vamiriri ava vanogonesa mast masero kana basophil, kungave zvakananga kana zvisina kunangana.

Chekupedzisira, pane "dzidziso yekuremara kwemaseru." Iyi dzidziso inoti vanhu vane CIU vane hurema mune mast cell kana basophil kutengesa, kuratidza, kana kushanda. Izvi zvinotungamira kune yakawandisa histamine kuburitswa.

5. Pane here shanduko dzekudya dzandinofanira kuita kubata CIU yangu?

Isu hatigare tichikurudzira shanduko yekudya kugadzirisa CIU sezvo zvidzidzo zvisina kuratidza chero bhenefiti. Kugadziriswa kwekudya hakusi kutsigirwa nemitemo yakawanda yekubvumirana.

Kunamatira kuzvikafu, senge yakaderera-histamine kudya, zvakare kwakanyanya kuoma kutevera. Zvakakoshawo kuti uzive kuti CIU haisi mhedzisiro yechikafu chechokwadi, saka chikafu-allergy kuyedza hakuwanzo kuva nezvibereko.

6. Ndeapi matipi aunazvo ekuziva zvinokonzeresa?

Pane zvakawanda zvinozivikanwa zvinoita kuti mikoko yako iwedzere. Kupisa, doro, kumanikidza, kupesana, uye kushushikana mupfungwa zvinotaurwa zvakanaka kuti zviwedzere zviratidzo.

Pamusoro pezvo, iwe unofanirwa kufunga nezvekudzivirira asipurini uye mamwe asiri -steroidal anti-anogumbura zvinodhaka (NSAIDs). Vanogona kuwedzera CIU mune dzakawanda zviitiko. Iwe unogona kuenderera mberi kutora yakaderera-dosi, yevana aspirin painoshandiswa kudzivirira kuwanda kweropa.

7. Ndedzipi nzira dzekurapa dzepamusoro dzandinogona kuedza?

OTC non-sedating antihistamines, kana H1 blockers, inokwanisa kudzora mikoko kune ruzhinji rwevanhu vane CIU. Izvi zvigadzirwa zvinosanganisira loratadine, cetirizine, levocetirizine, uye fexofenadine. Iwe unogona kutora kanokwana kana iro rinokurudzirwa rezuva rega rega pasina kukura mhedzisiro.

Iwe unogona zvakare kuyedza sedating antihistamine sekudikanwa, senge diphenhydramine. H2-ichivharira antihistamine, senge famotidine uye ranitidine, inogona kupa zororo rakawedzerwa.

8. Ndeapi marapirwo anogona kupihwa nachiremba wangu?

Dzimwe nguva, antihistamines (ese H1 uye H2 blockers) haakwanise kubata mikoko uye kuzvimba kwakabatana neCIU. Kana izvi zvikaitika, zviri nani kushanda pamwe nebhodhi-rakasimbiswa allergist kana immunologist. Vanogona kupa mishonga inopa kudzora kuri nani.

Chiremba wako anogona kuyedza kusimba sedating, mushonga antihistamine kutanga senge hydroxyzine kana doxepin. Ivo vanogona gare gare kuyedza omalizumab kana iyi mishonga isingashande mukurapa zviratidzo zvako.

Isu hatiwanzo kukurudzira muromo corticosteroids kune vanhu vane CIU. Izvi zvinokonzerwa nekukwanisa kwavo kweakakosha mhedzisiro. Mamwe ma immunosuppressants anowanzo shandiswa mune zvakakomba, zvisingadzoreke kesi.

Marc Meth, MD, akagamuchira degree rake rekurapa kubva kuDavid Geffen Chikoro cheMishonga kuUCLA. Akapedzisa kugara kwake muInternal Medicine kuMount Sinai Hospital muNew York City. Akazopedzisa kuyanana muAllergy & Immunology kuLong Island Jewish-North Shore Medical Center. Dr. Meth parizvino vari paChipatimendi cheKiriniki kuDavid Geffen Chikoro cheMishonga kuUCLA uye vane rombo rakanaka kuCedars Sinai Medical Center. Iye ari maviri Mumiriri weAmerican Board yeInternal Medicine uye iyo American Board yeAllergy & Immunology. Dr. Meth vari muchiitiko chega muCentury City, Los Angeles.