Bvunza Nyanzvi: Dr. Amesh Adalja paNew Hepatitis C Marapirwo

Zvemukati

• Chii chinonzi Hepatitis C, uye Chinosiyana Sei Nemamwe Mhando dzeHepatitis?
• Ndedzipi Ndidzo Dzidzo dzeKurapa?
• Ndedzipi Mhando dzeMarapirwo Matsva Ari Kuwana Ground, uye Anoratidzika Sekuti Anoshanda Sei?
• Aya marapiro matsva Akaenzana Sei neakajairwa Marapirwo?
• Varwere Vanofanirwa Sei Kuita Kurapwa Kwavo Sarudzo?

Takabvunzurudza Dr. Amesh Adalja, nyanzvi yezvirwere zvinotapukira neUniversity of Pittsburgh Medical Center, nezve zvakaitika kwaari pakurapa hepatitis C (HCV). Nyanzvi mumunda, Dr. Adalja anopa muongororwo weHCV, kurapa kwakajairika, uye marapirwo matsva anonakidza anogona kuchinja mutambo wevarwere vehepatitis C kwese kwese.

Chii chinonzi Hepatitis C, uye Chinosiyana Sei Nemamwe Mhando dzeHepatitis?

Hepatitis C rudzi rwehutachiona hepatitis hwakasiyana nemamwe marudzi ehutachiona hepatitis mukuti ine tsika yekugara isingagone uye inogona kutungamira kuchiropa cirrhosis, gomarara rechiropa, uye zvimwe zvehurongwa hwehurongwa. Iyo inobata ingangoita muUS uye zvakare iri chikonzero chinotungamira chekudiwa kwekuisirwa chiropa. Inopararira kuburikidza neropa rekuratidzwa senge kuwedzerwa ropa (kusati kwaongororwa), jekiseni kushandisa zvinodhaka uye kashoma kuburikidza nekubatana pabonde. Hepatitis A haina chimiro chisingaperi, mushonga unodzivirirwa, unoparadzirwa nenzira yemuromo, uye hautungamire kuchiropa cirrhosis uye / kana gomarara. Hepatitis B, zvakare inotakurwa neropa uye zvakare inokwanisa kukonzera chiropa cirrhosis nekenza, mushonga unodzivirirwa uye unopararira zviri nyore kuburikidza nekusangana pabonde uye kubva kuna amai kuenda kuvana vavo panguva yekuzvitakura nekuzvara. Hepatitis E yakafanana nehepatitis A asi, mune zvisingawanzoitika zviitiko, inogona kuve isingagumi, uye zvakare ine mwero wepamusoro wekufa mumadzimai akazvitakura.

Ndedzipi Ndidzo Dzidzo dzeKurapa?

Iwo makosi ekurapwa kwehepatitis C anoenderana zvachose nerudzi rwe hepatitis C imwe yauri kuchengeta. Kune matanhatu genotypes ehepatitis C uye mamwe ari nyore kurapa kupfuura mamwe. Muzhinji, kurapwa kwehepatitis C kunosanganisira musanganiswa wemishonga miviri kana mitatu, kazhinji inosanganisira interferon, inotarisirwa kweanenge vhiki gumi nembiri.

Ndedzipi Mhando dzeMarapirwo Matsva Ari Kuwana Ground, uye Anoratidzika Sekuti Anoshanda Sei?

Mushonga mutsva unonyanya kufadza ndeye antiviral drug sofosbuvir, iyo yakaratidzirwa kuti haina kungoshanda zvakanyanya chete, asi zvakare ine kugona kupfupisa makosi ekurapa kubva pamirefu yakareba isati yatanga.

Sofosbuvir inoshanda nekudzivirira iyo enzyme yehutachiona RNA polymerase. Iyi ndiyo nzira inoshandiswa nehutachiona kugadzira makopi acho pachawo. Mumakiriniki ekuyedza uyu mushonga, pamwe chete, wakaratidzirwa kuve unoshanda zvakanyanya pakutsikirira hutachiona nekukurumidza uye nekusimba, uchibvumira kupfupiswa kwakakosha kwerejimeni yekurapa. Kunyangwe mimwe mishonga yakanangisa iyi enzyme, dhizaini yechirwere ichi ndeyekuti inokurumidza uye nenzira inoshandurwa kuita chimiro chayo mukati memuviri, ichibvumira kudzivirirwa kwakasimba kweiyo enzyme. Sofosbuvir aive

Zvakare, mune dzimwe nguva, kusanganiswa kwezvinodhaka izvo zvisingabatanidze interferon-inotyiwa nekuda kwayo isingafadzi mhedzisiro mhedzisiro - inogona zvakare kushandiswa. [Kunyange ichishanda, interferon inozivikanwa nekukonzeresa kuora mwoyo uye zviratidzo zvakaita sefuru. Sofosbuvir ndiyo yekutanga mushonga yakatenderwa neDFA kuti ishandiswe pasina kubatana-kweyekupindirana kweferferon mune zvimwe zviitiko.]

Aya marapiro matsva Akaenzana Sei neakajairwa Marapirwo?

Mukana, sezvandambotaura pamusoro apa, ndewekuti marimu matsva mapfupi, anoshivira, uye anoshanda. Izvo zvisina kunaka ndezvekuti mishonga mitsva inodhura zvakanyanya. Nekudaro, kana munhu akatarisa mamiriro azere, ayo anosanganisira mari yekuvandudza zvinodhaka zvakaitiswa, nekuda kwekugona kudzivirira zvakanyanya-uye zvinodhura-zvinetso zvehutachiona hweH hepatitis C, mishonga mitsva iyi inogamuchirwa kuwedzera kune arsenal.

Varwere Vanofanirwa Sei Kuita Kurapwa Kwavo Sarudzo?

Ndingakurudzira kuti varwere vaite sarudzo dzekurapa vachibatana nachiremba wavo mushure mekukurukurirana nezvechizvino mamiriro ehutachiona hwavo, chimiro chiripo chiropa chavo, uye kugona kwavo kutevedzera mushonga.