Bvunza iyo Nyanzvi: Chii Chaunofanira Kuziva Nezve Yako HER2 + Kuziva

Zvemukati

• 1. Chii chaizvo chinoreva HER2-positive?
• 2. Ndichada kuvhiyiwa here? Kana zvirizvo, ndedzipi sarudzo dzangu?
• 3. Ndedzipi nzira dzekurapa dziripo?
• 4. Ndezvipi zvinangwa zvekurapa?
• 5. Ndeupi maonero eHER2-positive kenza yemazamu?
• 6. Pane here zvimwe zvinokanganisa kurapwa, uye ndingazvigadzirisa sei?
• 7. Pane here mararamiro andinofanira kuita mushure mekuongororwa kwangu?
• 8. Ndeipi njodzi yangu yekutapukirwa nekenza yemazamu yeHER2?

1. Chii chaizvo chinoreva HER2-positive?

HER2-positive inomiririra munhu epidermal kukura chinhu chinogamuchira 2. Masero mumuviri anowanzo gamuchira mameseji ekukura nekupararira kubva kune zvinogamuchirwa zviri kunze kwesero. Izvi zvinogamuchirwa zvine hanya nema enzymes akasiyana, kana vatumwa, izvo zvinogadzirwa mumuviri. Iwo ma receptors anogadzirisa akasiyana maseru uye ovaudza zvekuita (kureva, kukura, kupararira, kana kufa).

Izvi zvinogamuchirwa zviriwo kunze kwemasero ekenza. Asi, maseru ekenza anogona kunge aine akawanda anogamuchira kupfuura akajairwa sero. Iyi nhamba yakawedzera, pamwe nedzimwe shanduko dzakatenderedza kenza yesero, inovatendera kuti vagamuchire mamwe mameseji ekukura nekupararira kana achienzaniswa neakajairika, asina maseru ane cancer. Tinodaidza ma receptors aya "oncodrivers," zvichireva kuti vanofambisa kenza kuti ikure.

Muzviitiko izvi, gomarara rinogona kunyanya kutsamira pane iwo ma receptors kuti arambe achikura nekupararira. Kana izvi zvinogamuchirwa zvakavharwa uye zvisingabvumirwe kugamuchira mameseji, sero harigone kukura kana kupararira.

MuHER2-inovhenekera kenza yemazamu, iyo nhamba yeHER2-yakanaka inogamuchira kunze kwesero yakakura kudarika zvaingave mune yakajairwa, isina gomarara sero. Izvi zvinobatsira kutyaira gomarara kukura nekupararira.

2. Ndichada kuvhiyiwa here? Kana zvirizvo, ndedzipi sarudzo dzangu?

Yako oncology timu ichaona kana iwe uchida kuvhiyiwa uye kurukura kuti ndeupi rudzi rwekuvhiya kwakanakira iwe. Zvinhu zvakawanda zvakasiyana zvinopinda mukusarudza kuti ndeupi rudzi rwekuvhiyiwa kwaunofanira kuitwa uye nguva yekuvhiyiwa (kungave pamberi kana mushure mekurapwa systemic). Vanachiremba vako vanokurukura zvaunogona kuita newe zvakadzama, uye pamwe chete, munogona kusvika pamutongo.

3. Ndedzipi nzira dzekurapa dziripo?

Sarudzo dzekurapa dzinosanganisira radiation radiation, kuvhiya, chemotherapy, uye endocrine therapy. Iwe zvakare uchave nekwaniso ekurapa ayo anonanga zvakananga HER2 receptors.

Zvinhu zvakawanda zvinosarudza mhando uye nguva yekurapwa yauchazogamuchira. Izvi zvinosanganisira zera rako, mamwe mamiriro ehutano, danho rekenza, uye zvaunofarira. Yako oncology timu inofanirwa kukurukura dzese nzira dzekurapa dziripo kune yako chaiyo kesi.

4. Ndezvipi zvinangwa zvekurapa?

Zvinangwa zvekurapa zvinoenderana nedanho rekenza yemazamu iwe yaunenge uchiongorora. Kune avo vane danho 0 kusvika ku3 gomarara repazamu, chinangwa chekurapa ndechekurapa kenza uye kudzivirira kudzokazve mune ramangwana.

Chikamu chechina chegomarara repazamu zvinoreva kuti gomarara rapararira kupfuura zamu uye lymph node dzemuno. Panguva ino, chinangwa chekurapa kudzora kukura kwegomarara uye kudzivirira chero kukuvara kwemuviri kana kurwadziwa.

Nehurombo, danho rechina gomarara repazamu harigone kurapwa. Asi nekuuya kwemishonga mitsva uye mitsva, zvinokwanisika kugara munguva yechirwere chakatsiga kwenguva yakareba.

5. Ndeupi maonero eHER2-positive kenza yemazamu?

Iko kutarisa kweHER2-yakanaka kenza yemazamu kunoenderana nezvinhu zvishoma zvakasiyana. Izvi zvinosanganisira danho rekenza, kugona kwako kutsungirira kurapwa, zera rako, uye hutano hwako.

Kuuya kwemishonga mitsva yakawanda uye inoshanda yakanangwa inoshanda pamwe chete nemamwe marapirwo inoramba ichivandudza maonero evakadzi vane kenza yemazamu yeHER2.

6. Pane here zvimwe zvinokanganisa kurapwa, uye ndingazvigadzirisa sei?

Kurapa mhedzisiro kunoenderana nerudzi rwekurapa kwaunosangana nako. Muzhinji, varwere vanogona kushivirira monoclonal antibodies anoshandiswa kunongedza HER2-positive receptors zvakanaka.

Mimwe mhedzisiro yemhedzisiro inosanganisira kuneta, kurwadziwa pamwe chete, kurwadziwa nemusoro, uye kushaya hope. Mazhinji emhedzisiro iyi madiki mukuomarara.

Kazhinji, monoclonal antibodies anoshandiswa kurapa HER2-yakanaka kenza yemazamu inogona kukonzera kushomeka kwemitsipa yemwoyo. Yako oncology timu inokurukura nezve njodzi iyi newe uye nekukutarisa zvakanyanya kune chero zviratidzo zveichi chisingawanzo kuomarara.

7. Pane here mararamiro andinofanira kuita mushure mekuongororwa kwangu?

Kazhinji, iwe unofanirwa kutevedzera mararamiro ane hutano mushure mekuongororwa kwekenza yemazamu. Rega kuputa kana uchisvuta, gumisa kunwa doro kune chimwe chinwiwa kana zvishoma pazuva, uye ita zvine mwero zuva nezuva.

Iwe unofanirwa zvakare kutevera chikafu chine hutano chakakwirira muzvibereko, miriwo, uye mashoma-mafuta mapuroteni. Deredza kudya kwako kweshuga yakanatswa uye chikafu chine mafuta mazhinji.

8. Ndeipi njodzi yangu yekutapukirwa nekenza yemazamu yeHER2?

Mune varwere vane yekutanga-nhanho HER2-yakanaka kenza yemazamu (nhanho 0 kusvika 3), makore gumi-emuno ekudzokazve kwekupona ari pakati pe79 kusvika 95 muzana. Mhando yacho inoenderana nedanho rekenza pakuongororwa uye nemhando yekuvhiyiwa.

Nekudaro, zvinhu zvakawanda zvinogona kukonzera njodzi yako yekudzokazve. Kurukura nezvengozi yako wega neboka rako reoncology.

Zano rakapihwa naHope Qamoos, mukoti murapi mune hutano hwevakadzi. Tariro ane makore anopfuura gumi nemashanu ezviitiko achishanda muhutano hwevakadzi uye oncology. Akapedza rake rehunyanzvi basa achishanda nevatungamiriri vemaonero vatungamiriri mumunda kuzvipatara zveyunivhesiti zvakaita seStanford, Northwestern, uye Loyola. Pamusoro pezvo, Tariro anoshanda nechikwata chakasiyana-siyana chine chinangwa chekuvandudza kuchengetwa kwevakadzi vane kenza muNigeria.