Eculizumab - ndeyei
Zvemukati
Eculizumab inorwisa monoclonal antibody, inotengeswa nekutengesa pasi pezita raSoliris. Iyo inovandudza mhinduro yekuzvimba uye inoderedza kugona kwemuviri pachako kurwisa masero eropa, ichinyanya kuratidzirwa kurwisa chirwere chisingawanzo chinonzi husiku paroxysmal hemoglobinuria.
Chii ichochi
Mushonga Soliris unoratidzwa pakurapa chirwere cheropa chinonzi paroxysmal nocturnal hemoglobinuria; chirwere cheropa neitsvo zvinodaidzwa kuti atypical hemolytic uremic syndrome, panogona kunge paine thrombocytopenia uye kupererwa neropa, mukuwedzera kune kugwamba kweropa, kuneta uye kusashanda zvakanaka kwenhengo dzakasiyana siyana, zvichiratidzwawo pakurapa kwakajairwa Myasthenia gravis.
Mutengo
MuBrazil, uyu mushonga unogamuchirwa naAnvisa, uye unoitwa kuti uwanikwe neSUS kuburikidza nematare edzimhosva, asiri kutengeswa muma pharmacy.
Kushandisa sei
Mushonga uyu unofanirwa kuiswa sejekiseni muchipatara. Kazhinji, kurapwa kunoitwa nedrip kupinda mutsinga, kweinenge maminitsi makumi mana nemashanu, kamwe chete pasvondo, kwemasvondo mashanu, kudzamara gadziriso yaitwa kune iyo dosi yekushandisa ese mazuva gumi nemashanu.
Main mhedzisiro
Eculizumab inowanzo tenderwa, iyo inonyanya kuve kutanga kwemusoro. Nekudaro, mhedzisiro senge thrombocytopenia, yakaderera masero matsvuku eropa, kurwadziwa mudumbu, kuzvimbirwa, manyoka, kusagadzikana kugaya, kusvotwa, kurwadziwa pachipfuva, kutonhora, kupisa muviri, kuzvimba, kuneta, kushaya simba, herpes, gastroenteritis, kuzvimba kunogona kuitikawo. , arthritis, pneumonia, meningococcal meningitis, kurwadziwa kwemhasuru, kurwadziwa musana, kurwadziwa kwemutsipa, dzungu, kuderera kwekuravira, kurira mumuviri, kumisikidza nekukasira, kukosora, kutsamwa kwehuro, mhino dzakazara, muviri unoruma, kudonha kubva kubvudzi, ganda rakaoma.
Kana isingashandiswe
Soliris haifanire kushandiswa muvanhu vanogonana nechero ipi yeiyo fomula, uye kana zvikaitika kuti utachiona husina kugadziriswa Neisseria meningitidis, vanhu vasina mushonga wekubata meningitis.
Mushonga uyu unongofanirwa kushandiswa mukuzvitakura, pasi pezano rezvechiremba uye kana zvichinyatso kudikanwa, nekuti unopfuura nepanzvimbo uye unokanganisa kutenderera kweropa kwemwana. Kushandiswa kwaro hakuna kuratidzwa panguva yekuyamwisa, saka kana mukadzi achiyamwa, anofanira kumira kwemwedzi mishanu mushure mekushandisa mushonga uyu.