Enbrel vs. Humira yeRheumatoid Arthritis: Rutivi-ne-Rutivi Kuenzanisa

Zvemukati

• Mhedziso
• Basics paEnbrel neHumira
• Zvinodhaka zvinowirirana parutivi
• Kuchengetedza zvinodhaka
• Mutengo, kuwanikwa, uye inishuwarenzi
• Zvimwe zvinokanganisa
• Kubatana kwezvinodhaka
• Shandisa nemamwe marapirwo
• Taura nachiremba wako

Mhedziso

Kana iwe uine rheumatoid arthritis (RA), imi mese munoziva zvakanyanya nemhando yekurwadziwa uye kuomarara kwemajoini izvo zvinogona kuita kuti kunyange kusimuka pamubhedha mangwanani kurwa.

Enbrel naHumira mishonga miviri inogona kubatsira. Tarisa uone zvinoitwa nemishonga iyi uye nemabatiro avanozviita.

Basics paEnbrel neHumira

Enbrel naHumira mishonga yemishonga inoshandiswa kurapa RA.

Ose maviri emishonga iyi bundu necrosis factor (TNF) alpha inhibitors. TNF alpha ipuroteni inogadzirwa nema immune system. Inobatsira mukuzvimba uye kukuvara kwemajoini.

Enbrel naHumira vanovhara chiito cheTNF alpha iyo inotungamira kukuvara kubva kune isina kujairika kuzvimba.

Nhungamiro dzazvino hadzikurudzire TNF inhibitors senzira yekutanga kurapwa kweRA. Pane kudaro, vanokurudzira kurapwa neDMARD (senge methotrexate).

Kunze kweRA, vese Enbrel naHumira vanobatawo:

• juvenile idiopathic arthritis (JIA)
• psoriatic arthritis (PsA)
• ankylosing spondylitis
• plaque psoriasis

Uye zvakare, Humira anobatawo:

• Chirwere cheCrohn
• urikanwi colitis (UC)
• hidradenitis suppurativa, mamiriro eganda
• uveitis, kuzvimba muziso

Zvinodhaka zvinowirirana parutivi

Enbrel naHumira vanoshanda nenzira imwechete yekurapa RA, uye mazhinji maficha avo akafanana.

Nongedzo hadziratidze kusarudzika kweimwe TNF inhibitor pamusoro peimwe, nekuda kwekushayikwa kweuchapupu hunogutsa kuti imwe inoshanda kupfuura imwe.

Vamwe vanhu vanobatsirwa nekuchinjira kune yakasiyana TNF inhibitor kana yekutanga isingashande, asi mazhinji echiremba angakurudzira kuchinjira kune rakasiyana RA mushonga panzvimbo.

Iyi tafura inotevera inoratidza zvinoitwa nemishonga iyi miviri:

Iwe unogona kuona kuti Enbrel SureClick Autoinjector neHumira matanga akanyorwa zviri nyore uye zviri nyore kushandisa kupfuura majekiseni akafanirwa. Vanoda matanho mashoma.

Vanhu vanowanzoona mamwe mabhenefiti eimwe mishonga mushure memaviri kusvika matatu madosi, asi kuyedzwa kwakaringana kwemushonga kunenge mwedzi mitatu kuti vaone kubatsirwa kwavo kwakazara.

Maitiro anoita munhu mumwe nemumwe kune chero chinodhaka achasiyana.

Kuchengetedza zvinodhaka

Enbrel naHumira zvakachengetwa zvakafanana.

Ose maviri anofanirwa kuchengetwa mubhokisi rekutanga kudzivirira kubva pachiedza kana kukuvara kwemuviri. Mamwe matipi ekuchengetedza anoonekwa pazasi:

• Chengetedza mushonga mufiriji pane tembiricha iri pakati pe36 ° F uye 46 ° F (2 ° C uye 8 ° C).
• Kana uchifamba, chengetedza mushonga patembiricha (68-77 ° F kana 20-25 ° C) kwemazuva gumi nemana.
  • Chengetedza mushonga kubva pachiedza uye mwando.
  • Mushure memazuva gumi nemana pane tembiricha yemukati, kandira mushonga kure. Usadzorere mufiriji.
  • Usaisa chando mushonga kana kushandisa kana chando chobva chanyungudika.

Mutengo, kuwanikwa, uye inishuwarenzi

Enbrel naHumira zvinongowanikwa chete sezita remazita ezita, kwete majeniki, uye zvinodhura zvakafanana.

Iyo webhusaiti GoodRx inogona kukupa iwe yakanyanya yakajeka pfungwa nezve yavo yazvino, chaiyo mitengo.

Vazhinji vanopa inishuwarenzi vanoda mvumo yepamberi kubva kuna chiremba wako vasati vavhara uye kubhadhara kune chero yemishonga iyi. Tarisa nekambani yeinishuwarenzi kana khemisi kuti uone kana iwe uchida mvumo yepamberi yeEnbrel kana Humira.

Yako pharmacy inogona chaizvo kukubatsira iwe nemapepa kana mvumo ichidikanwa.

Mazhinji mafarmacy anotakura ese Enbrel neHumira. Zvisinei, izano rakanaka kushevedza pharmacy yako pamberi kuti uve nechokwadi chekuti mushonga wako urimo.

Biosimilars inowanikwa kune ese ari maviri madhiragi. Kana dzangove dziripo, biosimilars inogona kunge ichidhura kupfuura iyo yekutanga zita rechiratidzo mushonga.

Biosimilar yeEnbrel ndiErelzi.

Biosimilars mbiri dzeHumira, Amjevita naCyltezo, zvakagamuchirwa neU.S.Food and Drug Administration (FDA). Nekudaro, kana parizvino haina kuwanikwa yekutenga muUnited States.

Amjevita yakawanikwa muEurope muna 2018, asi hazvitarisirwi kurova misika yeUS kusvika 2023.

Zvimwe zvinokanganisa

Enbrel naHumira ndeveboka rimwe chete remishonga. Nekuda kweizvozvo, ivo vane mhedzisiro yakafanana.

Mimwe yemhedzisiro inowanzoitika inosanganisira:

• maitiro panzvimbo yejojo
• sinus chirwere
• musoro
• mapundu

Zvimwe zvakakomba mhedzisiro zvinogona kusanganisira:

• kuwedzera njodzi yekenza
• matambudziko etsinga
• matambudziko eropa
• nyowani kana kuwedzera moyo kutadza
• nyowani kana kuwedzera psoriasis
• neutachiona
• autoimmune maitiro
• hutachiona hwakakomba
• kudzvinyirira immune system

Mumwe wevanhu zana nemakumi manomwe nenomwe vakawana kuti adalimumab, kana Humira, vashandisi vaive nekanopfuura katatu mukana wekutaurira jekiseni / infusion-saiti kutsva uye kuruma mushure memwedzi mitanhatu yekurapwa.

Kubatana kwezvinodhaka

Nguva dzose rega chiremba wako azive nezvemishonga yose, mavitamini, kana mishonga yauri kutora. Izvi zvinogona kubatsira chiremba wako kudzivirira zvinobvira kudyidzana kwezvinodhaka, izvo zvinogona kuchinja mashandiro anoita mushonga wako.

Kudyidzana kunogona kukuvadza kana kudzivirira kuti mishonga isashande zvakanaka.

Enbrel naHumira vanobatana nemimwe mimwe mishonga. Kushandisa Enbrel kana Humira neinotevera majekiseni uye madhiragi zvinowedzera mukana wako wehutachiona:

• Urarame majekiseni, akadai se:
  • Varicella uye varicella zoster (chickenpox) majekiseni
  • herpes zoster (shingles) majekiseni
  • FluMist, inopinza inopfuudza furuwenza
  • gwirikwiti, mamora, uye rubella (MMR) wekudzivirira
  • zvinodhaka zvinoshandiswa kudzvinyirira immune system yako seakanakinra (Kineret) kana abatacept (Orencia)
• Mimwe mishonga yekenza, yakadai se cyclophosphamide uye methotrexate
• Mimwe mimwe mishonga yeRA yakadai sa sulfasalazine
• Mimwe mishonga inogadziriswa neprotein inonzi cytochrome p450, inosanganisira:
  • warfarin (Coumadin)
  • cyclosporine (Neoral, Sandimmune)
  • theophylline

Shandisa nemamwe marapirwo

Kana uine hutachiona hwehepatitis B, kutora Enbrel kana Humira kunogona kumutsa hutachiona hwako. Izvi zvinoreva kuti iwe unogona kutanga kuona hepatitis B zviratidzo, senge:

• kuneta
• kushaya nzara
• kuita yero kweganda rako kana kuchena kwemeso ako
• kurwadziwa kurudyi kwedumbu rako

Utachiona hunoshanda hunogona zvakare kutungamira mukundikana kwechiropa uye kufa. Chiremba wako anoedza ropa rako kuti ave nechokwadi chekuti hauna hepatitis B usati wagamuchira chero eaya madhiragi.

Taura nachiremba wako

Enbrel naHumira zvakafanana zvinodhaka. Izvo zvinoshanda zvakaenzana pakubvisa zviratidzo zveRA.

Nekudaro, pane misiyano mishoma, mimwe yacho inogona kuita kuti ive nyore kuti iwe ushandise.

Semuenzaniso, Humira inogona kutorwa imwe neimwe vhiki kana vhiki, nepo Enbrel inogona kungotorwa vhiki nevhiki.Iwe unogona zvakare kuona kuti iwe unosarudza vamwe vanonyorera, senge mapeni kana autoinjectors. Iko kusarudza kunogona kusarudza kuti ndeupi mushonga waunosarudza.

Kuziva zvishoma nezve izvi zviviri zvinodhaka kunogona kubatsira iwe kutaura nachiremba wako kuti uone kana chimwe chazvo chiri sarudzo kwauri.