Nyore Nongedzo kune iyo Endocannabinoid System

Zvemukati

• Chinoshanda sei?
• Endocannabinoids
• Endocannabinoid receptors
• Enzymes
• Ndeapi mabasa ayo?
• Ko THC inopindirana sei neECS?
• CBD inoshanda sei neECS?
• Zvakadii nezve endocannabinoid kushomeka?
• Chinokosha

Iyo endocannabinoid system (ECS) yakaoma kunzwisisa sero-chiratidzo chiratidzo chakazivikanwa mukutanga kwema1990 nevatsvagurudzo vanoongorora THC, inozivikanwa cannabinoid. Cannabinoids ndiwo makemikari anowanikwa mu cannabis.

Nyanzvi dzichiri kuyedza kunzwisisa zvizere iyo ECS. Asi kusvika parizvino, isu tinoziva kuti inotamba chinzvimbo mukugadzirisa huwandu hwemabasa nemaitiro, kusanganisira:

• rara
• mafungiro
• kuda kudya
• ndangariro
• kubereka uye kubereka

ECS iripo uye inoshanda mumuviri wako kunyangwe iwe usingashandise cannabis.

Verenga pamusoro kuti udzidze zvakawanda nezveECS inosanganisira mashandiro ayo uye kubatana necannabis.

Chinoshanda sei?

IEEC inosanganisira zvinhu zvitatu zvakakosha: endocannabinoids, receptors, uye enzymes.

Endocannabinoids

Endocannabinoids, inonziwo endogenous cannabinoids, mamorekuru akagadzirwa nemuviri wako. Izvo zvakafanana ne cannabinoids, asi zvinogadzirwa nemuviri wako.

Nyanzvi dzakaona maviri akakosha endocannabinoids kusvika ikozvino:

• Anandamide (AEA)
• 2-arachidonoylglyerol (2-AG)

Izvi zvinobatsira kuchengetedza mabasa emukati achimhanya zvakanaka. Muviri wako unozviburitsa pazvinenge zvichidikanwa, zvichiita kuti zvive zvakaoma kuziva kuti ndeapi chaiwo matanho ari kune rimwe nerimwe

Endocannabinoid receptors

Izvi zvinogamuchirwa zvinowanikwa mumuviri wako wose. Endocannabinoids inosunga kwavari kuitira kuratidza kuti ECS inoda kutora matanho.

Pane maviri makuru endocannabinoid receptors:

• CB1 receptors, ayo anonyanya kuwanikwa munzvimbo yepakati tsinga
• CB2 receptors, ayo anonyanya kuwanikwa mune yako peripheral tsinga system, kunyanya immune maseru

Endocannabinoids inogona kusunga kune chero receptor. Iyo mhedzisiro inoguma inoenderana nekwaanogamuchira uye iyo endocannabinoid inosunga kwairi.

Semuenzaniso, endocannabinoids inogona kunongedza CB1 receptors mumutsipa wepelinha kubvisa marwadzo. Vamwe vanogona kusunga kune CB2 receptor mumasero ako ekudzivirira muviri kuratidza kuti muviri wako uri kuzvimba, chiratidzo chakajairika che autoimmune kusagadzikana.

Enzymes

Enzymes inokonzera kuputsa endocannabinoids kana vangoita basa ravo.

Kune mairi enzyme makuru anoita izvi:

• fatty acid amide hydrolase, iyo inoputsa AEA
• monoacylglycerol acid lipase, iyo inowanzo kupaza 2-AG

Ndeapi mabasa ayo?

Iyo ECS yakaoma, uye nyanzvi hadzisati dzaziva chaizvo kuti inoshanda sei kana ese ayo anogona kuita mabasa.

yakabatanidza ECS kune inotevera maitiro:

• kuda kudya uye kugaya
• metabolism
• kurwadziwa kusingaperi
• kuzvimba uye mamwe immune system mhinduro
• mafungiro
• kudzidza nekurangarira
• kudzora mota
• rara
• cardiovascular system basa
• kuumbwa kwemhasuru
• kugadzirisa mapfupa uye kukura
• chiropa chinoshanda
• kubereka system inoshanda
• kunetseka
• ganda uye tsinga basa

Aya mabasa ese anobatsira ku homeostasis, iyo inoreva kugadzikana kwenzvimbo yako yemukati. Semuenzaniso, kana simba rekunze, rakadai sekurwadziwa kubva mukukuvara kana fivhiri, rinokanda homeostasis yemuviri wako, ECS yako inorovera mukati kuti ibatsire muviri wako kudzokera mukushanda kwayo kwakakodzera.

Nhasi, nyanzvi dzinotenda kuchengetedza homeostasis kana iri rekutanga basa reECS.

Ko THC inopindirana sei neECS?

Tetrahydrocannabinol (THC) ndeimwe yeakanyanya cannabinoids inowanikwa mu cannabis. Ndiwo mukomboni unowana iwe "wakakwirira."

Kamwe mumuviri wako, THC inopindirana neECS yako nekusunga kune zvinogamuchirwa, kungofanana ne endocannabinoids. Iyo ine simba chikamu nekuti inogona kusunga kune ese ari maviri CB1 uye CB2 receptors.

Izvi zvinotendera kuti ive nemhando dzakasiyana dzemuviri wako nepfungwa, zvimwe zvinodikanwa kupfuura vamwe. Semuenzaniso, THC inogona kubatsira kudzikamisa marwadzo uye kukurudzira kuda kwako kudya. Asi zvinogona zvakare kukonzera paranoia uye kusagadzikana mune dzimwe nguva.

Nyanzvi pari zvino dziri kutsvaga nzira dzekugadzira synthetic THC cannabinoids iyo inosangana neECS munzira dzinobatsira chete.

CBD inoshanda sei neECS?

Imwe huru cannabinoid inowanikwa mu cannabis ndeye cannabidiol (CBD). Kusiyana neTHC, CBD haikuitise iwe "kukwirira" uye kazhinji haina kukonzera chero zvakashata mhedzisiro.

Nyanzvi hadzina chokwadi zvachose kuti CBD inopindirana sei neECS. Asi ivo vanoziva kuti haina kusunga kune CB1 kana CB2 receptors nenzira iyo THC inoita.

Pane kudaro, vazhinji vanotenda kuti inoshanda nekudzivirira endocannabinoids kubva pakuputswa. Izvi zvinovatendera kuti vave nezvakawanda zvinoitika pamuviri wako. Vamwe vanotenda kuti CBD inosunga kune inogamuchira iyo isati yawanikwa.

Nepo ruzivo rwekushanda kwarwo ruchiri pasi pekupokana, kutsvagisa kunoratidza kuti CBD inogona kubatsira nemarwadzo, kuda kurutsa, uye zvimwe zviratidzo zvine hukama nemamiriro mazhinji

Zvakadii nezve endocannabinoid kushomeka?

Dzimwe nyanzvi dzinotenda mune dzidziso inozivikanwa seyekupedzisira endocannabinoid kushomeka (CECD). Iyi dzidziso inoratidza kuti yakaderera endocannabinoid mazinga mumuviri wako kana ECS kusagadzikana kunogona kubatsira mukuvandudzwa kwemamwe mamiriro.

Kuongorora pamusoro pemakore gumi ekutsvaga pamusoro penyaya iyi kunoratidza kuti dzidziso yacho inogona kutsanangura kuti sei vamwe vanhu vachikura migraine, fibromyalgia, uye chirwere chetsinga.

Hapana cheaya mamiriro ane chikonzero chiri pachena chiri kukonzera. Ivo zvakare vanowanzo kupokana nekurapwa uye dzimwe nguva kunoitika padivi peumwe.

Kana CECD ikatamba chero mhando yemhando mune ino mamiriro, kunongedza iyo ECS kana endocannabinoid kugadzirwa kungave iri yekushayikwa kiyi yekurapa, asi kumwe kutsva kunodiwa.

Chinokosha

Iyo ECS inoita basa rakakura mukuchengetedza yako yemukati maitiro akagadzikana. Asi kuchine zvakawanda zvatisingazive nezvazvo. Sezvo nyanzvi dzichivandudza kunzwisiswa kuri nani kweECS, inogona kupedzisira yabata kiyi yekurapa akati wandei mamiriro.