G6PD Kushomeka

Zvemukati

• Ndezvipi zviratidzo zvekushomeka kweG6PD?
• Chii chinokonzera kushomeka kweG6PD?
• Ndezvipi zvinhu zvine njodzi yekushomeka kweG6PD?
• Kushomeka kweG6PD kunoonekwa sei?
• Kushomeka kweG6PD kunorapwa sei?
• Ndeapi maonero emumwe munhu ane kushomeka kweG6PD?

Chii chinonzi G6PD kushomeka?

Kushomeka kweG6PD kusarongeka kwemajini kunoguma nekukwana kuwanda kweglucose-6-phosphate dehydrogenase (G6PD) muropa. Iyi yakakosha enzyme (kana protein) iyo inodzora akasiyana siyana mamakemikari maitiro mumuviri.

G6PD inobatawo nekuchengetedza masero matsvuku eropa aine hutano kuitira kuti agone kushanda nemazvo uye kurarama hupenyu hwakajairwa. Pasina kukwana kwayo, masero matsvuku eropa anoputsika nguva isati yakwana. Uku kuparadzwa kwekutanga kwemasero matsvuku eropa kunozivikanwa se hemolysis, uye inogona kupedzisira yaendesa ku hemolytic kupererwa neropa.

Hemolytic anemia inokura apo masero matsvuku eropa anoparadzwa nekukurumidza kupfuura zvinoita muviri kutsiva, zvichikonzera kudzikira kweoksijeni inoenda kunhengo uye nyama. Izvi zvinogona kukonzera kuneta, kuita yero kweganda nemaziso, uye nekufema kwekufema.

Muvanhu vane kushomeka kweG6PD, hemolytic anemia inogona kuitika mushure mekudya fava bhinzi kana mamwe maruva. Inogona zvakare kukonzerwa nezvirwere kana nezvimwe zvinodhaka, zvakaita se:

• antimalarials, rudzi rwemishonga inoshandiswa kudzivirira uye kurapa malaria
• sulfonamides, mushonga unoshandiswa kurapa hutachiona hwakasiyana
• aspirin, mushonga unoshandiswa kubvisa fivhiri, kurwadziwa, uye kuzvimba
• mamwe nonsteroidal anti-anogumbura mishonga (NSAIDs)

Kushomeka kweG6PD kwakanyanya mu Africa, uko kunogona kukanganisa kusvika makumi maviri muzana yevagari. Mamiriro acho akajairika kuvarume kupfuura kuvakadzi.

Vanhu vazhinji vane kushomeka kweG6PD kazhinji havawani chero zviratidzo. Zvisinei, vamwe vanogona kukura zviratidzo pavanosangana nemishonga, chikafu, kana hutachiona hunokonzera kuparadzwa kwekutanga kwemasero matsvuku eropa. Kamwe chinokonzera chiri kurapwa kana kugadziriswa, zviratidzo zvekushomeka kweG6PD zvinowanzonyangarika mukati memavhiki mashoma.

Ndezvipi zviratidzo zvekushomeka kweG6PD?

Zviratidzo zvekushomeka kweG6PD zvinogona kusanganisira:

• kukurumidza kurova kwemoyo
• mweya wekufema
• weti yakasviba kana yero-orenji
• kupindwa nechando
• kuneta
• dzungu
• kuchena
• jaundice, kana kuita yero kweganda uye vachena vemeso

Chii chinokonzera kushomeka kweG6PD?

Kushomeka kweG6PD hunhu hwemhando inopfuudzwa kubva kune mumwe kana vaviri vabereki kuenda kumwana wavo. Iyo isina kukwana geni inokonzeresa kushomeka iri pane X chromosome, inova imwe yemaviri echromosomes ebonde. Varume vane X imwe chete chromosome, nepo vakadzi vane maX chromosomes maviri. Muvanhurume, imwe yakashandurwa kopi yegene yakaringana kukonzera kushomeka kweG6PD.

Mune vanhukadzi, zvakadaro, shanduko yaifanirwa kunge iripo mumakopi ese ejeni. Sezvo zvisinganyanyoita kuti vanhukadzi vave nemaviri akashandurwa emhando iyi, vanhurume vanokanganiswa nekushomeka kweG6PD zvakanyanya kupfuura vakadzi.

Ndezvipi zvinhu zvine njodzi yekushomeka kweG6PD?

Unogona kuve nenjodzi yakakwira yekushomeka kweG6PD kana iwe:

• varume
• vari veAfrica -America
• ndeve Middle East dzinza
• uve nenhoroondo yemhuri yemamiriro acho

Kuva nechimwe chete kana zvimwe zvezvipingamupinyi hazvireve kuti uchave nekushomeka kweG6PD. Taura nachiremba wako kana iwe uine hanya nenjodzi yako yemamiriro acho.

Kushomeka kweG6PD kunoonekwa sei?

Chiremba wako anogona kuongorora kushomeka kweG6PD nekuita ongororo yeropa yakapfava kuti atarise mazinga enzyme eG6PD.

Dzimwe bvunzo dzekuongorora dzinogona kuitwa dzinosanganisira yakazara yakazara kuverenga ropa, serum hemoglobin bvunzo, uye reticulocyte kuverenga. Yese bvunzo iyi inopa ruzivo nezve masero matsvuku eropa mumuviri. Vanogona zvakare kubatsira chiremba wako kuti aone hemolytic anemia.

Munguva yako yekugadzwa, zvakakosha kuudza chiremba wako nezvechikafu chako uye chero mishonga yauri kutora izvozvi. Idzi ruzivo dzinogona kubatsira chiremba wako nekuongororwa.

Kushomeka kweG6PD kunorapwa sei?

Kurapa kwekushomeka kweG6PD kunosanganisira kubvisa chinokonzeresa chiri kukonzera zviratidzo.

Kana iyo mamiriro akakonzerwa nehutachiona, saka hutachiona hwepasi hunorapwa zvinoenderana. Chero chero mishonga yazvino ingave iri kuparadza masero matsvuku eropa inomiswawo. Mune zviitiko izvi, vanhu vazhinji vanogona kupora kubva muchiitiko chavo vega.

Kamwe kushomeka kweG6PD kwaenda kumberi kuhemolytic anemia, zvisinei, kurapwa kwakanyanya kunogona kudikanwa. Izvi dzimwe nguva zvinosanganisira kurapwa kweoksijeni uye kuwedzerwa ropa kuti uzadze okisijeni uye masero masero eropa.

Iwe unozofanirwa kugara muchipatara iwe uchinge uchinge uchinge uchirapwa, sekunyatso tarisisa kweakakomba hemolytic anemia kwakakosha kuti uve nechokwadi chekuzorora zvizere pasina zvinetswa.

Ndeapi maonero emumwe munhu ane kushomeka kweG6PD?

Vanhu vazhinji vane kushomeka kweG6PD havana kana zviratidzo. Avo vanorwara zvakakwana kubva kuzviratidzo zvavo kana kurapwa kuchinge kwagamuchirwa kune iko kunokonzeresa mamiriro acho. Zvisinei, zvakakosha kuti udzidze maitiro aungaita mamiriro acho uye kudzivirira zviratidzo kubva mukukura.

Kugadzirisa kushomeka kweG6PD kunosanganisira kudzivirira chikafu nemishonga inogona kukonzera mamiriro acho. Kuderedza kushungurudzika kunogona kubatsira mukudzora zviratidzo. Kumbira chiremba wako chinyorwa chakadhindwa chemishonga uye chikafu chaunofanirwa kudzivirira.