Chii chinonzi insulinoma, zviratidzo zvikuru uye kurapwa

Zvemukati

• Zviratidzo zvikuru
• Maitiro ekuongororwa kunoitwa
• Kurapa nzira
• 1. Kuvhiya
• 2. Hormonal mishonga uye insulin regulators
• 3. Chemotherapy
• 4. Ablation uye arterial embolization
• Zvinogona kukonzerwa

Insulinoma, inozivikanwawo seislet cell tumor, imhando yemota mupancreas, benign kana yakaipa, iyo inoburitsa yakawandisa insulin, ichiita kuti glucose yeropa iderere, ichigadzira hypoglycemia. Zviratidzo zvinokonzerwa nebundu iri zvinogona kuita dzungu, kuvhiringidzika kwepfungwa, kudedera uye kushanduka kwemanzwiro uye kunoitika nekuda kweglucose dysregulation muropa.

Kuongororwa kwe insulinoma kunoitwa neye endocrinologist kana oncologist kuburikidza nekuongororwa kweropa, sekutsanya glucose uye imaging bvunzo, iyo inogona kuverengerwa tomography, yemagineti resonance imaging kana pet pet scan, uye kurapwa kwakanyanya ndiko kuvhiya, mishonga mahormone uye kudzora ropa mazinga eshuga, pamwe nekemotherapy, ablation kana embolization.

Zviratidzo zvikuru

Insulinoma rudzi rwechirwere chiri mupancreas inoshandura mwero wehuga yeropa uye, nekudaro, zviratidzo zvikuru zvine chekuita nekuderedza shuga yeropa, inonzi hypoglycemia, senge:

• Kukanganiswa kana kuona kaviri;
• Kuvhiringidzika kwepfungwa;
• Dzungu;
• Kunzwa kushaya simba;
• Kunyanyisa kutsamwa;
• Maitiro anochinja;
• Kufenda;
• Kuwedzera kutonhora ziya.

Mune zvimwe zviitiko zvakakomba, apo insulinoma yanyanya kuwedzera uye ikabata zvimwe zvikamu zvemuviri, zvakaita sechiropa, huropi neitsvo, zviratidzo zvakaita sekubatwa, kuwedzerwa kwemoyo, kurasikirwa kwekuziva, kufenda uye jaundice kunogona kuoneka. Dzidza zvakawanda nezve jaundice uye maitiro ekuzviziva.

Maitiro ekuongororwa kunoitwa

Kuongororwa kwe insulinoma kunoitwa kuburikidza nekuongororwa kweropa, uko kunofanirwa kuitwa pasina chinhu mudumbu, kuona huwandu hweshuga uye insulin muropa uye, kazhinji, glucose kukosha ari mashoma uye insulin mazinga akakwirira. Tarisa uone kuti iyo yekutsanya yeropa glucose bvunzo inoitwa sei uye zvakajairwa mareferensi maitiro

Kuti uwane iyo chaiyo nzvimbo, saizi uye mhando yemota iri mupancreas uye kutarisa kana insulinoma yapararira kune mamwe mativi emuviri, imaging bvunzo senge computed tomography, magnetic resonance imaging kana pet pet scan zvinoratidzwa ne endocrinologist kana oncologist.

Mune mamwe mamiriro ezvinhu, chiremba anogona zvakare kuraira kumwe kuyedzwa kuti kubatsire kuongororwa uye kuziva kukura kweiyo bundu senge endoscopy, iyo inoshandiswa kuongorora kana bundu rasvika mukati medumbu kana ura, uye arteriography, inozivisa iyo kuyerera kweropa mupancreas.

Kurapa nzira

Insulinoma rudzi rwebundu mupancreas, iro rinogona kunge riine hutachiona kana kuti rakaipa, izvo zvinotungamira kuchinjiro mumazinga eropa, uye kana ikarapwa nekukurumidza inogona kurapwa. Mushonga werudzi urwu rwechirwere unoratidzwa ne oncologist uye zvinoenderana nenzvimbo, saizi uye nhanho yebundu, pamwe nekuvapo kwemastastases, uye inogona kukurudzirwa:

1. Kuvhiya

Kuvhiya ndiyo yakakodzera mhando yekurapa insulinoma, zvisinei, kana bundu riri mupancreas rakakura kwazvo, rapararira kune dzimwe nhengo dzomuviri kana munhu ari muhutano husina kunaka, chiremba anogona kusakurudzira kuita oparesheni. Kana kuvhiya kukaitwa, murwere angangoda kushandisa dhureini, inonzi penrose, kubvisa zvinwiwa zvakaunganidzwa panguva yekuvhiya. Ona zvimwe maitiro ekuchengeta iyo yekudonha mushure mekuvhiyiwa.

2. Hormonal mishonga uye insulin regulators

Mimwe mishonga inogona kushandiswa kurapa insulinoma, senge mishonga inoderedza kana kunonoka kugadzirwa kwemahormone anoita kuti bundu rikure, senge somatostatin analogue, inonzi octreotide uye lanreotide.

Mimwe mishonga inoratidzwa pakurapwa kwechirwere cherudzi urwu mishonga inobatsira kudzikisa insulin mumuropa, kudzivirira kuwanda kweglucose. Uye zvakare, chikafu chepamusoro-shuga chinogona kugadzirwa kuitira kuti mazinga eglucose ave akajairika.

3. Chemotherapy

Chemotherapy inokurudzirwa nachiremba oncologist kurapa insulinoma ine metastasis uye inove nekushandisa kwemishonga mutsinga kuti iparadze masero asina kujairika, ayo anotungamira mukukura kwebundu, uye huwandu hwezvikamu uye mhando yemishonga ichave inoshandiswa zvinoenderana nehunhu hwechirwere, senge saizi nenzvimbo.

Zvisinei, mishonga inonyanya kushandiswa kubvisa insulinoma maseru doxorubicin, fluorouracil, temozolomide, cisplatin uye etoposide. Iyi mishonga inowanzo kupihwa muserum, kuburikidza nekatheta mutsinga uye, mune dzimwe nguva, inopfuura imwe yadzo inogona kushandiswa, zvichienderana neprotocol yakagadzwa nachiremba.

4. Ablation uye arterial embolization

Radiofrequency ablation ndiyo mhando yekurapa inoshandisa kupisa, inogadzirwa nemasaisai eredhiyo, kuuraya anorwara insulinoma maseru uye inokodzera kwazvo kurapa tumamota tusina kupararira kune dzimwe nhengo dzemuviri.

Kufanana nekubvisa, arterial embolization inzira yakachengeteka uye inokatyamadza, inokurudzirwa nachiremba oncologist yekurapa madiki insulinomas uye inosanganisira kuiswa kwehumwe mvura, kuburikidza nekateti, kudzivirira kuyerera kweropa mubundu, kubatsira kubvisa maseru ane chirwere. .

Zvinogona kukonzerwa

Izvo chaizvo zvinokonzeresa insulinoma hazvisati zvanyatsotsanangurwa, asi zvinowanzo kukura zvakanyanya mumadzimai kupfuura varume, muvanhu vari pakati pemakore makumi mana nemakumi matanhatu ekuberekwa uye vane chirwere chemageneti senge rudzi rwe1 neurofibromatosis kana tuberous sclerosis Dzidza zvakawanda nezve tuberous sclerosis uye marapirwo ayo.

Pamusoro pezvo, kuva nezvimwe zvirwere zvakaita seyeendocrine neoplasia, iyo inokonzeresa kukura kusingaite kwemasero mune endocrine system, uye Von Hippel-Lindau syndrome, iyo inogarwa nhaka uye inotungamira mukuonekwa kwemakwenzi mumuviri wese, inogona kuwedzera mikana yekuonekwa insulinoma .