Invasive Ductal Carcinoma Kurapa

Zvemukati

• Kurapa inopinda ductal carcinoma
• Kurapa kwemunharaunda
• Zvirongwa zvehurongwa
• Chemotherapy yechisimba ductal carcinoma
• Targeted Therapies
• Kutora

Chii chinonzi invasive ductal carcinoma?

Vanenge madzimai mazana maviri nemakumi matanhatu nematanhatu muUnited States vanozoonekwa vaine chirwere chegomarara repazamu muna2019. Rudzi rwegomarara rwepamazamu rwunonyanya kunzi invasive ductal carcinoma (IDC). Inotarisirwa nezve makumi masere muzana ezvese chirwere chegomarara repazamu.

Carcinoma inoreva mhando yekenza inotangira mumasero eganda kana zvinyama zvinonamira nhengo dzemukati. Adenocarcinomas mamwe akasarudzika marudzi eacarcinomas ayo anotangira mune yeglandular tishu yemuviri.

Invasive ductal carcinoma, inozivikanwawo seinopinza ductal carcinoma, inowana zita rayo nekuti inotangira mumukaka unotakura mukaka wechipfuva, uye inopararira kune (kana inopinda) yakapoteredza matishu emuzamu. Iyi miviri miviri yakajairika yekenza yemazamu inopinda ndeiyi:

• Inopisa ductal carcinoma. Maakaundi e80 muzana yekenza yemazamu kuongororwa. Rudzi urwu runotanga mukati uye rwunopararira kubva munzira dzemukaka.
• Inopisa lobular carcinoma. Maakaunzi e10 muzana yekenza yemazamu kuongororwa. Rudzi urwu runotanga mumakaka-anoburitsa lobules.

Kunyange IDC ichikanganisa vakadzi pazera ripi zvaro, inowanzoonekwa mumadzimai ane makore makumi mashanu kusvika makumi matanhatu nemana. Gomarara repazamu iri rinogona kubatawo varume.

Kurapa inopinda ductal carcinoma

Kana iwe kana mumwe munhu waunoziva akaonekwa aine IDC, zorora uine nzira dzakasiyana dzekurapa dziripo.

Kurapa kweIDC kunowira mumhando mbiri huru:

• Mishonga yemuno yeIDC inotarisa kenza yemazamu uye nenzvimbo dzakatenderedza, senge chifuva uye lymph node.
• Masystemic ekurapa IDC anoshandiswa mumuviri wese, achitarisa chero maseru anogona kunge akafamba uye akapararira kubva pabundu rekutanga. Zvirongwa zvehurongwa zvinoshanda pakuderedza mukana wekuti gomarara rinodzoka kana rarapwa.

Kurapa kwemunharaunda

Kune maviri akakosha marudzi ekurapa kwenzvimbo kweIDC: kuvhiya uye radiation radiation.

Kuvhiya kunoshandiswa kubvisa bundu rine gomarara uye kuona kana gomarara rapararira kune ma "lymph node". Kuvhiya kunowanzoitwa mhinduro yekutanga kwechiremba pakubata neIDC.

Zvinotora angangoita mavhiki maviri kuti uwanezve kubva kune lumpectomy uye masvondo mana kana kupfuura kuti uwanezve kubva kune mastectomy. Nguva dzekudzoreredza dzinogona kuve dzakareba kana lymph node dzakabviswa, kana kuvakwazve kwaitwa, kana kana paine chero matambudziko.

Dzimwe nguva kurapwa kwepanyama kunogona kukurudzirwa kuti ubatsire kupora kubva pane izvi maitiro.

Radiation Therapy inotungamira matanda emwaranzi ane simba pazamu, pachipfuva, muhapwa, kana muhuro kuuraya chero maseru anogona kunge ari mukati kana padyo nenzvimbo yebundu. Radiation kurapa kunotora ingangoita maminetsi gumi kuitisa zuva nezuva pamusoro pesvondo shanu kusvika sere.

Vamwe vanhu vanorapwa nemwaranzi vanogona kuona kuzvimba kana shanduko yeganda. Zvimwe zviratidzo, senge kuneta, zvinogona kutora kusvika kumavhiki matanhatu kusvika gumi nemaviri kana kupfuura kuti zvidzikire.

Mhando dzakasiyana dzekuvhiya uye radiation nzira dzekurapa dzinowanikwa pakurapa iyi IDC dzinosanganisira:

• lumpectomy, kana kubviswa kwebundu
• mastectomy, kana kubviswa kwezamu
• lymph node kupatsanura uye kubvisa
• kunze kwedanda radiation, mune iwo mwaranzi matanda anotarisa kwese zamu nzvimbo
• yemukati yakasarudzika-yemazamu mwaranzi, umo radioactive zvinhu zvinoiswa padhuze nenzvimbo ye lumpectomy
• kunze kwekusarura-chifuva chemazamu, umo mazhenje emwaranzi anotarisa zvakananga kunzvimbo yepenza yekenza

Zvirongwa zvehurongwa

Zvirongwa zvehurongwa zvinogona kukurudzirwa zvichienderana nehunhu hwekenza, kusanganisira mumamiriro ezvinhu apo yakatopararira kupfuura zamu kana iri panjodzi huru yekupararira kune dzimwe nhengo dzemuviri.

Zvirongwa zvehurongwa zvakadai chemotherapy zvinogona kupihwa kudzikisira bundu (s) pamberi pekuvhiyiwa, kana kupihwa mushure mekuvhiyiwa, zvinoenderana nemamiriro ezvinhu.

Masystemic ekurapa IDC anosanganisira:

• chemotherapy
• hormonal kurapa
• zvakanangwa kurapwa

Chemotherapy yechisimba ductal carcinoma

Chemotherapy inosanganisira anticancer mishonga inotorwa mupiritsi fomu kana kujowa muropa. Zvinogona kutora kusvika kumwedzi mitanhatu kana kupfuura mushure mekunge kurapwa kwadzikira kuti uwanezve kubva kumazhinji mhedzisiro, senge kukuvara kwetsinga, kurwadziwa kwemajoini, uye kuneta.

Kune akawanda akasiyana chemotherapy mishonga yekurapa ICD senge paclitaxel (Taxol) uye doxorubicin (Adriamycin). Taura nachiremba wako nezve izvo zvakakunakira iwe.

Hormonal kurapa kweinokuvadza ductal carcinoma

Hormonal therapy inoshandiswa kurapa kenza maseru nema receptors eestrogen kana progesterone, kana ese ari maviri. Kuvapo kweaya mahormone kunogona kukurudzira maseru ekenza yemazamu kuti awande.

Hormonal therapy inobvisa kana kuvhara aya mahormoni kubatsira kudzivirira cancer kuti isakura. Hormonal therapy inogona kuve nemhedzisiro inogona kusanganisira kupisa kupisa uye kuneta, uye kuti zvinotora nguva yakareba sei kuti mhedzisiro ipere mushure mekupedza kurapwa kunogona kusiyanisa zvichienderana nemushonga uye kureba kwekutonga.

Mimwe mishonga yekurapa kwehomoni inotorwa kazhinji kwemakore mashanu kana anopfuura. Mhedzisiro inogona kutora chero kubva pamwedzi yakati wandei kusvika pagore kana kupfuura kupfeka kana kurapwa kwamira.

Mhando dzehomoni yekurapa dzinosanganisira:

• inosarudza estrogen-receptor mhinduro modulators, iyo inovhara mhedzisiro yeestrogen pazamu
• aromatase inhibitors, iyo inoderedza estrogen kune postmenopausal vakadzi
• estrogen-receptor pasi-vanodzora, ayo anoderedza anowanikwa esrogen receptors
• ovarian kudzvinyirira mishonga, iyo inomisa kwechinguva mazai kubva mukugadzirwa kweestrogen

Targeted Therapies

Mishonga yakanangwa inoshandiswa kuparadza maseru ekenza yemazamu nekukanganisa nemamwe mapuroteni mukati memusero anokanganisa kukura. Mamwe mapuroteni anovavarira ndeaya:

• HER2
• VEGF

Kutora

Invasive ductal carcinoma ndiyo yakajairika mhando yekenza yemazamu. Kana zvasvika pakurapwa, kune marapirwo emuno anotarisa zvimwe zvikamu zvemuviri uye zvehurongwa zvekurapa zvinokanganisa muviri wese kana akawanda masisitimu enhengo.

Runopfuura rumwe rudzi rwekurapa runogona kudikanwa kuti unyatso kurapa gomarara repazamu. Taura nachiremba wako nezverudzi rwekurapa rwakakukodzera uye chakanakira nhanho yako yekenza yemazamu.