Chisingaperi Myeloid Leukemia: chii icho chiri, chinokonzeresa, zviratidzo uye kurapwa

Zvemukati

• Ndezvipi zviratidzo
• Zvinogona kukonzerwa
• Ndezvipi zvinhu zvine njodzi
• Chii chinonzi kuongororwa
• Kurapwa kunoitwa sei
• 1. Mishonga
• 2. Kupfupa kwemongo wemapfupa
• 3. Chemotherapy
• 4. Interferon kurapwa

Chisingaperi Myeloid Leukemia (CML) iri isingawanzo, isiri nhaka nhaka yekenza yeropa inokura nekuda kwekuchinja kwesero reropa majeni, ichivaita kuti vapatsanurane nekukurumidza kupfuura zvakajairika maseru.

Kurapa kunogona kuitiswa nemushonga, kupfuudzwa kwemongo wemapfupa, chemotherapy kana kuburikidza nemishonga yekurapa, zvichienderana nekukura kwedambudziko kana munhu anenge achirapwa.

Mikana yekurapa kazhinji yakanyanya kukwirira, asi inogona kusiyana zvichienderana nedanho rekukura kwechirwere, pamwe nezera uye hutano huzhinji hwemunhu akabatwa. Kazhinji, kurapwa pamwe neyakanakisa yekurapa mwero ndeyekupfupa kwemongo wemapfupa, asi vanhu vazhinji vangangodaro vasingatombofaniri kusvika kune iko kurapwa.

Ndezvipi zviratidzo

Zviratidzo nezviratidzo zvinogona kuitika muvanhu vane Chronic Myeloid Leukemia ndeizvi:

• Kakawanda kubuda ropa;
• Kuneta;
• Kupindwa nechando;
• Kurera huremu pasina chikonzero chiri pachena;
• Kurasikirwa nechido;
• Marwadzo pazasi pembabvu, kuruboshwe;
• Pallor;
• Kuwedzera kudikitira usiku.

Ichi chirwere hachikurumidze kuburitsa pachena zviratidzo nezviratidzo padanho rekutanga uye ndosaka zvichikwanisika kurarama nechirwere ichi kwemwedzi kana kunyangwe makore munhu asingazvizive.

Zvinogona kukonzerwa

Masero emunhu ane makumi maviri nematatu echromosomes, ayo ane DNA nemajini anopindira mukutonga kwemasero mumuviri. Mune vanhu vane Chronic Myeloid Leukemia, mumasero eropa, chikamu chechromosome 9 chinoshandura nzvimbo dzine chromosome 22, ichigadzira chromosome ipfupi kwazvo 22, inonzi Philadelphia chromosome uye chromosome yakareba kwazvo 9.

Iyi chromosome yePhiladelphia inozogadzira geni idzva, uye magene ari pachromosome 9 ne22 obva agadzira geni idzva rinonzi BCR-ABL, iro rine mirayiridzo inotaurira iyi nhare itsva isina kujairika kuti ibudise huwandu hwakawanda hweprotein inonzi tyrosine kinase., Iyo inotungamira mukuumbwa kwekenza nekubvumira maseru eropa akati wandei kukura kunze kwekudzora, ichikuvadza mwongo wepfupa.

Ndezvipi zvinhu zvine njodzi

Izvo zvinhu zvinogona kuwedzera njodzi yekuvandudza Chronic Myeloid Leukemia ndezvekuchembera, kuve murume uye kusangana nemwaranzi, senge radiation radiation inoshandiswa kurapa mamwe marudzi ekenza.

Chii chinonzi kuongororwa

Kazhinji, kana chirwere ichi chikafungidzirwa, kana kana kana kana zvimwe zviratidzo zvikaitika, kuongororwa kunoitwa uko kunosanganisira kuongororwa kwemuviri, sekuongororwa kwezviratidzo zvakakosha uye kuwedzerwa kweropa, kubatika kwenhengo dzemukati, spleen uye mudumbu, mukati nzira yekuona zvingangoitika zvisina kujairika.

Uye zvakare, zvakajairika kuti chiremba anyore bvunzo dzeropa, biopsy bone yemongo, iyo inowanzo kutorwa kubva muchiuno bone, uye bvunzo dzakasarudzika, senge fluorescent mu situ kusanganiswa kweongororo uye polymerase chain reaction test, inoongorora ropa kana mapfupa emongo ekuvapo kweiyo Philadelphia chromosome kana iyo BCR-ABL gene.

Kurapwa kunoitwa sei

Chinangwa chekurapa chirwere ichi kubvisa masero eropa ane geni risina kujairika, izvo zvinokonzeresa kugadzirwa kwenhamba huru yemasero eropa asina kujairika. Kune vamwe vanhu hazviite kubvisa ese maseru ane chirwere, asi kurapwa kunogona kubatsira mukuregererwa kwechirwere.

1. Mishonga

Mishonga inovhara chiito che tyrosine kinase inogona kushandiswa, senge Imatinib, Dasatinib, Nilotinib, Bosutinib kana Ponatinib, ayo anowanzo kuve ekutanga kurapwa kwevanhu vane chirwere ichi.

Iyo mhedzisiro mhedzisiro inogona kukonzerwa nemishonga iyi kuzvimba kweganda, kuda kurutsa, mhasuru cramp, kuneta, manyoka uye kugadzirisa kweganda.

2. Kupfupa kwemongo wemapfupa

Bone marrow kuisirwa ndiyo chete nzira yekurapa iyo inovimbisa kurapwa zvachose kweChirwere cheMyeloid Leukemia. Nekudaro, nzira iyi inongoshandiswa muvanhu vasingapindure kune mamwe marapirwo nekuti maitiro aya ane njodzi uye anogona kutungamira kumatambudziko akakomba.

3. Chemotherapy

Chemotherapy iri zvakare inoshandiswa zvakanyanya kurapwa muzviitiko zveSingaperi Myeloid Leukemia uye mhedzisiro yacho inoenderana nerudzi rwemishonga inoshandiswa pakurapa. Ziva mhando dzakasiyana dzekemotherapy uye kuti zvinoitwa sei.

4. Interferon kurapwa

Biological Therapies inoshandisa immune system yemuviri kubatsira kurwisa gomarara tichishandisa protein inonzi interferon, iyo inobatsira kudzikisa kukura kwemarara maseru. Iyi nzira inogona kushandiswa muzviitiko apo kumwe kurapwa kusingashande kana kune vanhu vasingakwanise kutora mimwe mishonga, senge vakadzi vane nhumbu, semuenzaniso.

Mhedzisiro inowanzoitika pakurapa uku, kuneta, kupisa muviri, zviratidzo zvakaita sefuru uye kuonda.