Chii chinonzi Burkitt's lymphoma, zviratidzo uye kurapwa kuri sei

Zvemukati

• Zviratidzo zvikuru
• Ndezvipi zvikonzero
• Maitiro ekusimbisa kuongororwa
• Mhando huru
• Kurapwa kunoitwa sei
• Burkitt's lymphoma inorapwa here?

Burkitt's lymphoma imhando yekenza yeiyo lymphatic system, iyo inonyanya kubata ma lymphocyte, anova maseru ekudzivirira emuviri. Gomarara iri rinogona kunge rakabatana nehutachiona nehutachiona hweEpstein Barr (EBV), hutachiona hwehutachiona hwehutachiona hweHIV, asi hunogona zvakare kumuka kubva mukuchinja kwemajini.

Kazhinji, rudzi urwu rwe lymphoma runokura zvakanyanya muvana vechirume kupfuura muvakuru uye kazhinji rwunokanganisa nhengo mudumbu. Nekudaro, nekuti iri kenza ine hukasha, umo masero egomarara anokura nekukurumidza, anogona kusvika kune dzimwe nhengo, senge chiropa, spleen, mwongo wemabhonzo uye kunyangwe mabhonzo echiso.

Chiratidzo chekutanga cheBurkitt's lymphoma kutaridzika kwekuzvimba mumutsipa, muhapwa, kugomera kana kuzvimba mudumbu kana kumeso, zvichienderana nenzvimbo yakabatwa neiyo lymphoma. Mushure mekuongorora zviratidzo, iyo hematologist ichasimbisa kuongororwa kuburikidza ne biopsy uye imaging bvunzo. Nekudaro, kuve nekusimbiswa kweBurkitt's lymphoma, kurapwa kwakakodzera kwazvo kunoratidzwa, uko kunowanzo kuve chemotherapy. Ona zvimwe kuti chemotherapy inoitwa sei.

Zviratidzo zvikuru

Zviratidzo zveBurkitt's lymphoma zvinogona kusiyana zvichienderana nerudzi uye nzvimbo yebundu, asi zviratidzo zvakajairika zverudzi urwu rwekenza ndezvi:

• Rurimi mumutsipa, muhapwa uye / kana kugomera;
• Kuwedzera kudikitira usiku;
• Kupindwa nechando;
• Kuonda pasina chikonzero chiri pachena;
• Kuneta.

Zvakajairika kuti Burkitt's lymphoma inokanganisa nharaunda yeshaya nemamwe mapfupa echiso, saka inogona kukonzera kuzvimba kune rumwe rutivi rwechiso. Nekudaro, bundu iri rinogona zvakare kukura mudumbu, zvichikonzera kuzvimba uye kurwadziwa mudumbu, kubuda ropa uye kutenderera kwematumbo. Kana iyo lymphoma ikapararira kuuropi, inogona kukonzera kushaya simba mumuviri uye kunetseka kufamba.

Uye zvakare, iko kuzvimba kunokonzerwa neBurkitt's lymphoma hakuwanzo kukonzera marwadzo uye kazhinji kunotanga kana kuwedzera mumazuva mashoma.

Ndezvipi zvikonzero

Kunyangwe hazvo zvikonzero zveBurkitt's lymphoma zvisina kunyatso kuzivikanwa, mune dzimwe mamiriro kenza iyi inosanganisirwa nehutachiona nehutachiona hweEBV neHIV. Uye zvakare, kuva nechirwere chekuzvarwa, ndiko kuti, kuzvarwa uine dambudziko remagene rinokanganisa kudzivirirwa kwemuviri, kunogona kusanganiswa nekuvandudzwa kwerudzi urwu rwe lymphoma.

Burkitt's lymphoma ndiyo yakajairika kenza yehucheche kumatunhu uko kune zviitiko zvemarariya, senge Africa, uye zvakajairika kune dzimwe nzvimbo dzenyika uko kune vana vazhinji vane hutachiona hweHIV.

Maitiro ekusimbisa kuongororwa

Sezvo Burkitt's lymphoma ichipararira nekukurumidza, zvakakosha kuti kuongororwa kwacho kuitwe nekukurumidza sezvazvinogona. Chiremba mukuru kana chiremba wevana anogona kufungidzira gomarara uye oendesa kune oncologist kana hematologist, uye mushure mekuziva kuti zviratidzo zvakaonekwa kare zvakadii, zvicharatidza mashandiro ebiopsy munzvimbo yebundu. Tsvaga kuti biopsy inoitwa sei.

Uye zvakare, kumwe kuyedzwa kunoitwa kuongorora Burkitt's lymphoma, senge computed tomography, magnetic resonance imaging, pet-scan, pfupa rekuunganidza uye CSF. Bvunzo idzi ndedze chiremba kuti vaone kuoma uye kukura kwechirwere uye vozotsanangura mhando yekurapwa.

Mhando huru

World Health Organisation inoronga Burkitt's lymphoma mumhando nhatu dzakasiyana, ndeiyi:

• Endemic kana Africa: zvinonyanya kubata vana vane makore mana kusvika pamakore manomwe uye zvakapetwa kaviri pane vakomana;
• Sporadic kana asiri-Africa: ndiyo mhando yakajairika uye inogona kuitika kuvana nevakuru pasirese, kuverenga kwehafu yenguva dzema lymphomas muvana;
• Yakabatana ne immunodeficiency: inoitika muvanhu vane hutachiwana hweHIV uye vane AIDS.

Burkitt's lymphoma inogona zvakare kuitika kune vanhu vanozvarwa vaine hutachiona hutachiona hunokonzeresa kushomeka kwekuzvidzivirira uye dzimwe nguva hunogona kukanganisa vanhu vakamboiswa uye vanoshandisa mishonga yekuzvidzivirira.

Kurapwa kunoitwa sei

Kurapa kweBurkitt's lymphoma kunofanirwa kutanga nekukurumidza kana kuongororwa kuchisimbiswa, sezvo iri mhando yemota inokura nekukurumidza. Iyo hematologist inokurudzira kurapwa zvinoenderana nenzvimbo yebundu uye nhanho yechirwere, asi kazhinji, kurapwa kwerudzi urwu rwe lymphoma kunoenderana nekemotherapy.

Iyo mishonga inogona kushandiswa pamwechete mu chemotherapy ndeye cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate uye cytarabine. Immunotherapy inoshandiswa zvakare, mushonga unonyanya kushandiswa uri rituximab, unosunga kumapuroteni mumasero ekenza achibatsira kubvisa cancer.

Intrathecal chemotherapy, inova mishonga inoiswa musana, inoratidzirwa kurapwa kweBurkitt's lymphoma muuropi uye inoshandiswa kudzivirira kuti isapararira kune dzimwe nhengo dzomuviri.

Nekudaro, mamwe marudzi ekurapa anogona kuratidzwa nachiremba, senge radiotherapy, kuvhiyiwa uye autologous bone marrow kuisirwa kana autotransplantation.

Burkitt's lymphoma inorapwa here?

Kunyangwe iri mhando ine hukasha yekenza, Burkitt's lymphoma inogara ichirapika, asi izvi zvinoenderana nekuti chirwere ichi chikaonekwa kupi, nzvimbo yakakanganiswa uye kana kurapwa kwakatangwa nekukurumidza. Kana chirwere ichi chikaonekwa padanho rekutanga uye kana kurapwa kuchizotanga mumashure, pane mukana mukuru wekurapa.

Burkitt's lymphomas muchikamu cheI ne II vane zvinopfuura makumi mapfumbamwe muzana zvemishonga, nepo lymphomas ine nhanho III uye IV ine avhareji ye80% mikana yekurapa.

Pakupera kwekurapa, zvichave zvakakodzera kuteedzera nahematologist kweanenge makore maviri uye kuita bvunzo mwedzi mitatu yega yega.

Tarisa uone vhidhiyo uine mamwe matipi ekuti ungatarise sei nekenza kurapwa zviratidzo: