Chiropa uye Cholesterol: Zvaunofanira Kuziva

Zvemukati

• Hutano hutano hwecholesterol mumuviri
• Chiropa chinoshanda matambudziko
• Nonalcoholic fatty chiropa chirwere
• Cirrhosis
• Zvinodhaka
• Mhedzisiro yeakakwira cholesterol
• Nguva yekuona chiremba
• Kuongorora
• Kurapa
• Ita
  
• Dzivisa
  
• Outlook
• Kudzivirira

Nhanganyaya uye pfupiso

Kuenzanisa cholesterol mwero kwakakosha kuchengetedza hutano hwakanaka. Chiropa chikamu chisinga zivikanwe cheichi chiito.

Chiropa ndiyo gland rakakura kwazvo mumuviri, iri muchikamu chepamusoro chedumbu. Iyo ishe tenzi detoxer yemishonga uye zvimwe zvekunze zvinhu. Iyo inochengeta glycogen, iyo iyo muviri unoshandisa kune simba. Izvo zvakakoshawo mukugadzirisa mafuta, makabhohaidhiretsi, uye mapuroteni. Chiropa chine hutano chinoita izvi zvese zvisingaonekwe.

Basa rakakosha rechiropa kugadzira uye kujekesa mumuviri. Mazhinji etarisiro anotarisana necholesterol anotsanangura kugona kwayo kwehutano hunokuvadza. Asi cholesterol inodiwa pakugadzira mahormone, vhitamini D, uye ma enzymes anodiwa pakugaya.

Mabundu anonzi lipoprotein anotakura cholesterol mumuviri wese. Mhando mbiri dzakakosha ihuru-density lipoproteins (HDL) uye yakaderera-density lipoproteins (LDL). "Kukwirira" uye "pasi" zvinoreva chikamu chakaenzana cheprotein kumafuta ari muhombodo. Muviri unoda mhando mbiri dziri muzvikamu zvakarongeka.

Hutano hutano hwecholesterol mumuviri

Zvakakosha kuziva mazinga eHDL ("yakanaka" cholesterol), LDL ("yakaipa" cholesterol), uye yakazara cholesterol mumuviri wako. Kufungidzira kwakashata kwecholesterol yakazara iHDL, pamwe neLDL, pamwe nehafu yechishanu yemhando yechitatu yemafuta inonzi triglyceride.

Iyo inokurudzira anotevera matanho:

HDL mazinga anosvika makumi mana emamirigiramu padhesilita (mg / dL) reropa. Chero chipi zvacho chakaderera pane icho chinowedzera njodzi yako yechirwere chemwoyo. Chikamu cheinenge 60 mg / dL inobatsira kudzikisa njodzi yako yechirwere chemwoyo.

Chiropa chinoshanda matambudziko

Chiropa chinoshanda matambudziko anogona kutadzisa kugona kwemuviri kuburitsa kana kujekesa cholesterol. Mamiriro ezvinhu ese ari maviri anogona kugadzira spike mu cholesterol uye kukanganisa hutano hwemunhu. Aya anotevera mamiriro anogona kukanganisa chiropa munzira iyo inokonzera cholesterol mazinga kuve asina kujairika.

Nonalcoholic fatty chiropa chirwere

Iyo yakajairika fomu yechiropa kusashanda ndeye nonalcoholic fatty chiropa chirwere (NAFLD). Iyo inobata ingangoita kota imwe yevagari. Inowanzoonekwa pakati pevanhu vakafuta zvakanyanya kana vane chirwere cheshuga.

NAFLD inosanganisirwa nedyslipidemia, akajairika mazinga echolesterol uye mamwe macomputer muropa. NAFLD zvakare inogona kukonzeresa, zvisina kufanira munzira iyo muviri unogovera mafuta.

NAFLD inovhara akasiyana mamiriro. Mukati me NAFLD ndiyo yakakomba isiri-doro steatohepatitis (NASH). Kuongororwa kweNASH kazhinji kunotungamira kuchirrhosis, kukundikana kwechiropa, uye hepatocellular carcinoma.

Cirrhosis

Cirrhosis inogona kukonzeresa uye kudzivirira chiropa kubva mukuita ekutanga metabolic mabasa. Mamiriro acho kuita kukuvara kwenguva refu kune nhengo. Kukuvara kunogona kusanganisira kuzvimba kubva kuchirwere chakadai hepatitis C. Mushure mehepatitis C, kunwa doro kwenguva refu ndicho chikonzero chakanyanya kukonzera cirrhosis muUnited States.

Zvinodhaka

Chimwe chikonzero chakakosha chechinetso chechiropa kukuvara kubva kumishonga. Basa rechiropa nderekugadzirisa mishonga mumuviri. Izvo zvinoita kuti zvinyanye kukuvara kubva kunyorerwo, pamusoro-iyo-iyo, kana zvinodhaka zvekuvaraidza.

Kazhinji zvinodhaka-zvinokonzerwa nekukuvara kwechiropa uye zvinodhaka zvinosanganiswa nemamiriro aya zvinosanganisira:

Chiropa hepatitis

Yakabatana mishonga:

• acetaminophen
• bromfenac
• isoniazid
• nevirapine
• ritonavir
• troglitazone

Chirwere hepatitis

Yakabatana mishonga:

• dantrolene
• diclofenac
• methyldopa
• minocycline
• nitrofurantoin

Yakasanganiswa pateni kana atypical hepatitis

Yakabatana mishonga:

• ACE inhibitors
• amoxicillin-clavulanic asidhi
• chlorpromazine
• erythromycin
• sulindac

Nonalcoholic steatohepatitis

Yakabatana mishonga:

• uchinetsa
• tamoxifen

Microvesicular steatosis

Yakabatana mishonga:

• NRTIs
• valproic asidhi

Veno-occlusive chirwere

Yakabatana mishonga:

• busulfan
• cyclophosphamide

Mushure mekumisa mushonga, chiropa chinokuvara kazhinji hachina kunyanya uye chinowanzodzikira. Muzviitiko zvisingawanzoitika, kukuvara kunogona kuve kwakanyanya kana kusingaperi.

Mhedzisiro yeakakwira cholesterol

Huwandu hwepamusoro hweLDL cholesterol hunowedzera njodzi yemafuta anoiswa pamidziyo inounza ropa kumoyo. Kuderera-kwakadzika kweiyo HDL cholesterol inoratidza kuti muviri unogona kusakwanisa kubvisa mabara uye mamwe mafuta anowanikwa mumuviri. Mamiriro ezvinhu ese ari maviri anounza njodzi yechirwere chemwoyo uye chirwere chemwoyo.

Nguva yekuona chiremba

Kukuvara kwechiropa kunogona kufambira mberi kwemwedzi kana makore pasina zviratidzo. Panguva iyo zviratidzo zvinoonekwa, kukuvara kwechiropa kazhinji kuri kwakawanda. Zvimwe zviratidzo zvinoratidza kushanya kwachiremba. Izvi zvinosanganisira:

• jaundice (yero ganda uye maziso)
• kuneta
• kushaya simba
• kurasikirwa nenzara
• kuunganidzwa kwemvura mukati medumbu
• maitiro ekupwanya nyore

Kuongorora

Chiremba anogona kukwanisa kuongorora matambudziko echiropa nekucherechedza zviratidzo zvako uye kupedzisa nhoroondo yezvokurapa. Iwe unogona zvakare kuita bvunzo yechiropa chako basa. Iyi bvunzo inosanganisira

Chiropa enzyme bvunzo: Ma enzymes akajairika mune ino pani pane alanine transaminase, aspartate transaminase, alkaline phosphatase, uye gamma-glutamyl transpeptidase. Mahombekombe epamusoro eimwe yeaya maenzyme anogona kuratidza kukuvara.

Chiropa protein bvunzo: Mashoma mashoma epuroteni globulin uye albin inogona kuratidza kurasikirwa kwechiropa basa. Prothrombin ipuroteni yechiropa inodiwa pakuvhara. Chiyero chakajairika chinotarisa kuti zvinotora nguva yakareba sei kuti ropa rako rigadzike. Inononoka kugwamba nguva inogona kureva kushomeka kweprothrombin uye kukuvara kwechiropa.

Bilirubin bvunzo: Ropa rinotakura bilirubin kuenda kuchiropa uye nduru. Ipapo inoburitswa muzvigaro. Ropa mumurini kana yakawandisa bilirubin muropa inogona kuratidza kukuvara kwechiropa.

Imwe lipoprotein pani: Iyo pani inoedza ropa cholesterol uye tryglycerides pamwechete. Ropa kazhinji rinotorwa mushure mekutsanya.

Kurapa

Kurapa kwehutano hwechiropa kazhinji kunotanga nekugadzirisa mamiriro ari pasi. Mamiriro akasiyana echiropa anoda nongedzo dzakasiyana dzekudya, asi iyo American Liver Foundation ine mamwe matipi.

Ita

• Idya zviyo, michero, miriwo, nyama uye bhinzi, mukaka uye mafuta zvakaenzana. Zvokudya zvine fiber-zvakakosha.
• Ramba uine hydrated.

Dzivisa

• chikafu chine mafuta mazhinji, shuga, uye munyu
• mbishi kana isina kubikwa hove
• doro

Kurapa kwecholesterol yakawanda kunosanganisira madhaidhi edzidziso senge echiropa chirwere. Kurapa kwecholesterol yakakwira zvakare kunowanzo sanganisira kirasi yemishonga inonzi inonzi statins. Vatsvakurudzi vakatarisa kana masitemu akachengeteka kune vanhu vane chirwere chechiropa kuti vashandise.

"Kazhinji, matemini akachengeteka muvarwere vane chirwere chechiropa," anodaro David Bernstein, MD, FACG, mukuru wehepatology kuNorthwell Health, uye purofesa wemishonga kuHofstra Northwell Chikoro cheMishonga muHempstead, NY. "Varwere vane decompens cirrhosis vanofanira kuongororwa zvakanyanya, asi kazhinji, vakachengeteka."

“Pane ngozi here? Hongu, asi idambudziko diki kwazvo uye varwere vanoongororwa mumwedzi mitatu kusvika mitanhatu yekutanga, ”anodaro Bernstein.

Outlook

Kurapa kupindira kunovimbisa kwakanyanya kudzora kwecholesterol, kunyangwe pakati pevanhu vane chirwere chechiropa. Asi mararamiro ehupenyu anochinja uye kudya kwekudya zvinoramba zvichikosha uye zvinoshanda zvikamu zveyese nzira yekudzora cholesterol nehutachiona hwechiropa

Kudzivirira

Izvo zvinoratidzira maitiro ekudzora akakwira mwero cholesterol muropa nekudya uye mararamiro uye shanduko:

Bernstein anongedzera aya marongero ehupenyu izano rakanaka kune chero munhu anoedza kuchengeta cholesterol mukutarisa, kusanganisira avo vane dambudziko rakawedzerwa rechirwere chechiropa.