Latuda (lurasidone): ndeyei, maitiro ekutora uye mhedzisiro
Zvemukati
Lurasidone, inozivikanwa nezita rekutengeserana Latuda, mushonga mukirasi yeantipsychotic, inoshandiswa kurapa zviratidzo zvechichichiphrenia uye kushushikana kunokonzerwa nebipolar kusagadzikana.
Mushonga uyu wakabvumidzwa nguva pfupi yadarika naAnvisa kutengeswa mumafarmacy muBrazil, mune 20mg, 40mg uye 80mg mapiritsi, mumapaketi emapiritsi e7, 14, 30 kana 60, uye anogona kuwanikwa kana kurairwa mumafarasi makuru. Sezvo iri antipsychotic, Lurasidone chikamu chechikamu chemishonga inodzorwa uye inotengeswa chete nemushonga wakasarudzika mumakopi maviri.
Chii ichochi
Lurasidone inoshandiswa kurapa:
- Schizophrenia, mune vakuru nevachiri kuyaruka vane makore gumi nematatu kusvika gumi nemasere;
- Kushungurudzika kwakabatana ne bipolar kusagadzikana, mune vanhu vakuru, semushonga mumwe kana mukubatana nevamwe, senge lithiamu kana valproate.
Mushonga uyu antipsychotic, inoshanda seyakavharira mumiriri wemhedzisiro yedopamine uye monoamine, ayo ari maurotransmitter ehuropi, akakosha mukuvandudza zviratidzo.
Nekudaro, inoshanda nekumwe kuvandudzwa zvine chekuita neyekare antipsychotic, senge shanduko diki mumetabolism, iine mashoma maitiro pakuwedzera uremu uye shanduko mumafuta emuviri uye glucose chimiro.
Sei kutora
Mahwendefa eLurasidone anofanirwa kutorwa nemuromo, kamwe chete pazuva, pamwe nekudya, uye zvinokurudzirwa kuti zvinwe panguva imwe chete zuva rega rega. Mukuwedzera, mahwendefa anofanira kumedzwa akazara, kudzivirira kunonaka kwavo.
Zvinogona kuitika mhedzisiro
Mimwe yemhedzisiro yemhedzisiro yeLurasidone kukotsira, kusagadzikana, dzungu, kufamba zvisina basa, kushaya hope, kushushikana, kushushikana kana kuwedzera huremu.
Mimwe mhedzisiro inokonzeresa kubatwa, kudonha kudya, kuneta, kusaona zvakanaka, tachycardia, shanduko muropa, dzungu kana shanduko mukuverenga kweropa, semuenzaniso.
Ndiani asingafanire kutora
Lurasidone inopesana pamberi pe:
- Hypersensitivity kune chinhu chinoshanda kana kune chero yeanoburitsa ari pahwendefa;
- Kushandiswa kweCYP3A4 yakasimba inodzivirira mishonga, yakadai seBoceprevir, Clarithromycin, Voriconazole, Indinavir, Itraconazole kana Ketoconazole, semuenzaniso;
- Kushandisa yakasimba CYP3A4 inducing zvinodhaka, senge Carbamazepine, Phenobarbital, Phenytoin, Rifampicin kana St John's wort, semuenzaniso.
Nekuda kwekudyidzana nemhedzisiro yemishonga iyi, rondedzero yemishonga inoshandiswa inofanirwa kugara ichiziviswa kuna chiremba anotevera.
Lurasidone inofanira kushandiswa nekuchenjerera nevanhu vane chirwere cheitsvo kana zvine mwero kusvika kune chakakomba chirwere chechiropa, chirwere cheParkinson, kusagadzikana kwekufamba, chirwere chemwoyo kana zvimwe zvirwere zvetsinga. Uye zvakare, uyu mushonga hauna kuyedzwa kune vakwegura varwere vane dementia kana muvana, saka kushandiswa kunofanirwa kudzivirirwa mune idzi kesi.