Noradrenaline
Zvemukati
Norepinephrine, inozivikanwawo se norepinephrine, mushonga unoshandiswa kudzora kukanganiswa kweropa mune mamwe acute hypotensive nyika uye sechibatiso pakurapa kusungwa kwemoyo uye kwakadzika hypotension.
Mushonga uyu unowanikwa sejekiseni, iro rinofanira kungoshandiswa chete pasi pezano rekurapa uye manejimendi aro anofanirwa kuitwa nenyanzvi yezvehutano.
Chii ichochi
Norepinephrine imushonga unoratidzirwa kudzora BP mune mamwe acute hypotensive nyika, mumamiriro ezvinhu senge pheochromocytomectomy, sympathectomy, polio, myocardial infarction, septicemia, kuwedzerwa ropa uye maitiro kumishonga.
Uye zvakare, inogona zvakare kushandiswa semubatsiro pakurapa kusungwa kwemoyo uye kwakadzika hypotension.
Kushandisa sei
Norepinephrine imishonga inofanirwa kupihwa chete nevezvehutano, mukati mehutano, mune mhinduro yakasununguka. Muyero unofanirwa kupihwa unofanirwa kuve wakasarudzika uye wakatarwa nachiremba.
Nzira yekuita
Norepinephrine inonzi neurotransmitter ine sympathomimetic chiitiko, inokurumidza kuita, ine yakadomwa mhedzisiro pane alpha-adrenergic receptors uye isinganyanyo kududzwa pane beta-adrenergic receptors. Nekudaro, kukosha kwayo kwakanyanya kunoitika mukusimudza BP, inova mhedzisiro yeanopa-inosimudzira mhedzisiro, inokonzeresa vasoconstriction, nekuderera kweropa kuyerera muitsvo, chiropa, ganda uye, kazhinji, skeletal musculature.
Ndiani asingafanire kushandisa
Noradrenaline haifanire kushandiswa mune vanhu vane hypersensitive kune izvo zvikamu zveiyo fomula kana ne mesenteric kana peripheral vascular thrombosis.
Uye zvakare, haifanire kupihwa kune vanhu vane hypotensive nekuda kwekushomeka kweropa, kunze kwekunge chimbichimbi chiyero chekuchengetedza coronary uye cerebral arterial perfusion kusvikira ropa reropa rekutsiva mushonga rikwanise kupera, kunyangwe panguva yeanesthesia ine cyclopropane uye halothane, sezvo ventricular tachycardia kana fibrillation inogona kuitika.
Zvinogona kuitika mhedzisiro
Mimwe mhedzisiro inogona kuitika mushure mekutarisirwa kwe norepinephrine kukuvara kwechischemic, kuderera kwemwoyo, kushushikana, kutemwa nemusoro kwenguva pfupi, kunetseka kufema uye necrosis panzvimbo yejekiseni.