Statins: Zvishandiso, Side Mhedzisiro, uye Zvimwe

Zvemukati

• Ndiani anogona kuvatora
• Mashandiro avo
• Kubatsirwa
• Mhando dzema statins
• Njodzi dzinogona kuitika uye mhedzisiro
• Tsvina kukuvara
• Kukuvara kwechiropa
• Kuwedzera njodzi yeshuga
• Taura nachiremba wako
• Q&A
• Mubvunzo:
• A:

Chii chinonzi statins?

Statins iboka remishonga inoshandiswa kurapa yakakwira cholesterol. Vanoshanda nekuderedza mwero wecholesterol muropa rako, kunyanya yakaderera-density lipoprotein (LDL) kana "yakaipa" cholesterol.

Vanhu vane yakakwira LDL cholesterol vari pangozi yakawanda yekuvandudza chirwere chemwoyo. Nemamiriro aya, cholesterol inovaka mukati medu artery uye inogona kutungamira kune angina, chirwere chemwoyo, kana sitiroko. Nekudaro, statins inogona kuve yakakosha mukuderedza idzi njodzi.

Ndiani anogona kuvatora

IAmerican Heart Association inokurudzira ma statins kune vamwe vanhu. Iwe pamwe nachiremba wako munofanira kufunga nezvezvimisikidzo kana imi:

• une LDL cholesterol mwero we190 mg / dL kana kupfuura
• atove nechirwere chemoyo
• vane makore makumi mana nemasere kusvika makumi manomwe neshanu ekuberekwa uye vane njodzi yakawandisa yechirwere chemoyo mukati memakore gumi anotevera
• vane chirwere cheshuga, vane makore makumi mana kusvika makumi manomwe neshanu ekuberekwa, uye vane mwero weLDL uri pakati pe70 ne189 mg / dL

Mashandiro avo

Muviri wako unonyatsoda imwe cholesterol kuti ishande zvakanaka. Muviri wako unowana cholesterol nekudya zvimwe zvekudya uye nekuzviita muchiropa chako. Zvisinei, njodzi dzinomuka apo cholesterol yako inowedzera zvakanyanya. Statins inoshanda kudzikisa cholesterol mwero mumuviri wako.

Statins ita izvi nekuvhara muviri wako kugadzirwa kweiyo enzyme inonzi HMG-CoA reductase. Iyi ndiyo enzyme iyo chiropa chako chinoda kugadzira cholesterol. Kuvhara iyi enzyme kunokonzera chiropa chako kuita cholesterol shoma, izvo zvinobva zvadzikisa cholesterol yako.

Statins inoshandawo nekuita kuti zvive nyore kuti muviri wako utore cholesterol iyo yatove yakavakwa mumatumbu ako.

Kubatsirwa

Kune akawanda akati wandei mabhenefiti ekutora mas statins, uye kune vanhu vazhinji, izvi mabhenefiti zvinopfuura nenjodzi dzemishonga.

Kliniki miedzo inoratidza kuti statins inogona kudzikisa LDL cholesterol mazinga neanosvika makumi mashanu muzana. Statins inogona zvakare kudzora njodzi yako yekurwadziwa kwemoyo uye sitiroko. Uye zvakare, yegore ra2010 inoratidza kuti zvimisikidzo zvinoita chikamu chidiki mukuderedza triglyceride mazinga nekusimudza HDL (yakanaka) cholesterol.

Statins ine anti-kupisa zvinhu zvinokanganisa mitsipa yeropa, moyo, uye huropi. Izvi zvinogona zvakare kudzikisa njodzi yeropa, kugumbuka kwemoyo, uye sitiroko.

Iyi mishonga inogona kubatsira zvakare kudzikisa mukana wekurambwa mushure mekuiswa kwechimwe nhengo, sekureva kwechinyorwa chiri muChinyorwa cheYedzo Yekurapa Mishonga. Zvisinei, kumwe kutsvagurudza kunodiwa munzvimbo ino.

Mhando dzema statins

Statins inowanikwa pasi pemhando dzakasiyana dzemhando dzakasiyana uye mazita, kusanganisira:

• atorvastatin (Lipitor, Torvast)
• fluvastatin (Lescol)
• lovastatin (Mevacor, Altocor, Altoprev)
• pitavastatin (Livalo, Pitava)
• pravastatin (Pravachol, Selektine)
• rosuvastatin (Crestor)
• simvastatin (Lipex, Zocor)

Mimwe mishonga yekubatanidza ine zvakare statins. Pakati pavo pane:

• amlodipine / atorvastatin (Caduet)
• ezetimibe / simvastatin (Vytorin)

Njodzi dzinogona kuitika uye mhedzisiro

Vanhu vanotora statins vanofanirwa kudzivirira grapefruit. Muchero wemazambiringa unogona kusangana nemamwe ma statins uye kuita mhedzisiro yakaipa. Izvi zvinonyanya kuitika ne lovastatin uye simvastatin. Ive neshuwa yekuverenga yambiro inouya nemishonga yako. Kana iwe uine mibvunzo, taura nachiremba wako kana wemishonga. Iwe unogona zvakare kuverenga zvakawanda nezve grapefruit uye statins.

Vanhu vazhinji vanogona kutora statins vasina yakawandisa mhedzisiro, asi mhedzisiro mhedzisiro inogona kuitika. Zvakaoma kutaura kana imwe mhando ye statin ichizokonzeresa mhedzisiro pane imwe. Kana iwe uchiramba uine mhedzisiro, chiremba wako anogona kunge achikwanisa kuyera dosi yako kana kukurudzira imwe statin.

Mimwe yemhedzisiro yakajairika yemhedzisiro inosanganisira:

• kuvimbiswa
• manyoka
• kusvotwa

Iyi mhedzisiro inowanzo kuve yakapfava. Nekudaro, zvimiso zvinogona zvakare kukonzera zvakakomba mhedzisiro. Izvi zvinosanganisira:

Tsvina kukuvara

Statins inogona kukonzeresa kurwadziwa kwemhasuru, kunyanya mune yakakwira madosi. Mune zvisingawanzoitika zviitiko, ivo vanogona kutokonzeresa mhasuru maseru kutsemuka. Kana izvo zvikaitika, ako maseru maseru anoburitsa protein inonzi myoglobin muropa rako. Aya mamiriro anonzi rhabdomyolysis. Inogona kukonzera kukuvara kwakakomba kuitsvo dzako. Ngozi yemamiriro aya yakakura kana iwe ukatora mimwe mishonga ine ma statins, kunyanya lovastatin kana simvastatin. Iyi mimwe mishonga inosanganisira:

• mamwe maantifungal akadai itraconazole uye ketoconazole
• cyclosporine (Restasis, Sandimmune)
• erythromycin (EES, Erythrocin Stearate, nevamwe)
• gemfibrozil (Lopid)
• nefazodone (Serzone)
• niacin (Niacor, Niaspan)

Kukuvara kwechiropa

Chiropa kukuvara ndechimwe chinogoneka chakakomba mhedzisiro mhedzisiro ye statin therapy Chiratidzo chekukuvara kwechiropa ndiko kuwedzera kwemakemikari echiropa. Usati watanga kutora statin, chiremba wako angangoita zviyero zvechiropa kuti atarise enzyme yako yechiropa. Vanogona kudzokorora bvunzo kana iwe ukaratidza zviratidzo zvechiropa matambudziko uchitora mushonga. Zviratidzo izvi zvinogona kusanganisira jaundice (yero yeganda rako uye nevachena vemeso ako), rima weti, uye kurwadziwa munzvimbo yepamusoro yekurudyi yedumbu rako.

Kuwedzera njodzi yeshuga

Statins inogona zvakare kukonzera iyo glucose (shuga) mazinga muropa rako kumuka. Izvi zvinokonzeresa kuwedzera kudiki mungozi yako yerudzi rwechipiri chirwere cheshuga. Kana iwe uine hanya nenjodzi iyi, taura nachiremba wako.

Taura nachiremba wako

Kutora statin uchitevera kudya kunovaka muviri uye kugara uchirovedza muviri inzira yakanaka yekuti vanhu vazhinji vadzikise cholesterol yavo. Kana uine cholesterol yakawanda, bvunza chiremba wako kana statin ingava sarudzo yakanaka kwauri. Mibvunzo iwe yaunogona kubvunza chiremba wako inosanganisira:

• Ndiri kutora chero mishonga inogona kusangana nesitina?
• Ndezvipi zvimwe zvakanaka zvaunofunga kuti statin inogona kundipa?
• Une kudya uye mazano ekurovedza muviri ayo anogona kundibatsira kudzikisa cholesterol yangu here?

Q&A

Mubvunzo:

Zvakachengeteka here kushandisa statins nedoro pamwechete?

Asingazivikanwe murwere

A:

Kana iwe uri kutora statin, ive shuwa yekutaura nachiremba wako nezve kana zvakachengeteka kuti iwe unwe doro. Kana ukangonwa doro rakati wandei uye uine chiropa chine hutano, zvingangove zvakachengeteka kuti iwe ushandise doro nema statin pamwechete.

Iko kunetseka kukuru nedoro uye statin kushandiswa kunouya kana iwe uchinwa kakawanda kana kunwa zvakanyanya, kana kana uine chirwere chechiropa. Mune zviitiko izvi, kusanganiswa kwedoro uye statin kushandiswa kunogona kuve nenjodzi uye kutungamira mukukuvara kwakanyanya kwechiropa. Kana iwe ukanwa kana uine chirwere chechiropa, ita chokwadi chekubvunza chiremba wako nezve njodzi yako.

Iyo Healthline Medical TeamMhinduro dzinomiririra iwo mafungiro evanachiremba vedu vezvekurapa. Zvese zvirimo ndezvechokwadi zvine ruzivo uye hazvifanire kutorwa sezano rekurapa.