Glomerular Filtration Rate (GFR): zvazviri, maitiro ekuzviona uye kana zvichizoshandurwa

Zvemukati

• Iyo GFR yakatemwa sei
• Zvakajairika GFR kukosha

Iyo glomerular filtration rate, kana inongori GFR, chiyero cherabhoritari iyo inobvumidza mushandi wezvese uye nephrologist kuongorora mashandiro eitsvo dzemunhu, chinova chakakosha chiyero chekuongororwa uye kuongororwa kweiyo nhanho yechirwere chisingaperi cheitsvo (CKD) , izvo zvinoita kuti GFR ive zvakare yakakosha ekumisikidza yakanyanya kurapwa, kana zvichidikanwa.

Kuti uverenge iyo glomerular firita chiyero, zvakafanira kuti utarise nezve munhu bonde, huremu uye zera, sezvo zvakajairika kuti GFR iderere seye munhu zera, kwete hazvo kuratidza kukuvara kwetsvo kana shanduko.

Pane huwandu hwakawanda hwakaverengerwa kuona iyo glomerular firita chiyero, zvisinei izvo zvinonyanya kushandiswa mukiriniki yekuita ndezve izvo zvino funga nezve huwandu hwe creatinine muropa kana huwandu hwe cystatin C, inova ndiyo yakanyanya kudzidza nhasi, kubvira iyo Mari ye creatinine inogona kutambura kupindirwa kubva kune zvimwe zvinhu, kusanganisira chikafu, nekudaro kusava chakakodzera chiratidzo chekuongororwa uye kuongorora kweCKD.

Iyo GFR yakatemwa sei

Iyo glomerular filtration rate inoonekwa murabhoritari uchishandisa masvomhu ayo anofanirwa kutarisisa kunyanya zera remunhu uye murume, sezvo izvi zvinhu zvichikanganisa mhedzisiro. Zvisinei, kuitira kuti GFR iverengwe, sampuli yeropa inofanira kuunganidzwa kuitira kuyera creatinine kana cystatin C, sekurudziro yechiremba.

Iyo glomerular filtration rate inogona kuverengerwa ese achifunga nezve kusangana kwe creatinine uye kuwanda kwe cystatin C. Kunyangwe creatinine iri iyo inonyanya kushandiswa, haisi iyo inonyanya kukodzera, sezvo kusangana kwayo kunogona kutambura kupindirwa kubva kune zvimwe zvinhu, senge chikafu, kurovedza muviri, hosha dzekuzvimba uye huwandu hwesimba mhasuru uye nekudaro hazvireve kuti zvinomirira itsvo kushanda

Kune rimwe divi, cystatin C inogadzirwa nemaseru enucleated uye inogara ichisefetwa muitsvo, kuitira kuti kusangana kweichi chinhu muropa kwakanangana neGFR, nekudaro ichi chiratidzo chepo cheitsvo.

Zvakajairika GFR kukosha

Iyo glomerular filtration rate inovavarira kuongorora kushanda kweitsvo, sezvo ichifunga muyero wezvinhu zvinosvinwa muitsvo uye zvisina kudzoserwa muropa, zvichinyanya kubviswa mumuti. Panyaya ye creatinine, semuenzaniso, puroteni iyi inosvinwa neitsvo uye hushoma hunodzoreredzwa muropa, kuitira kuti pasi pemamiriro ezvinhu akajairika, kuwanda kwe creatinine mumuti weti zvakanyanya kupfuura iro reropa kunogona kuongororwa.

Nekudaro, kana paine shanduko muitsvo, iyo nzira yekusefa inogona kuchinjwa, kuitira kuti pave nemusiki mushoma ari kusefa neitsvo, zvichikonzera kuwanda kwakanyanya kwe creatinine muropa uye kuderera kwe glomerular filtration rate.

Sezvo glomerular filtration rate inogona kusiyana zvichienderana nehunhu hwemunhu uye zera, iyo GFR inokoshesa kana kuverenga kwacho kunoitwa ne creatinine ndeiyi:

• Zvakajairika: yakakura kudarika kana yakaenzana ne60 mL / min / 1.73m²;
• Renal kusakwana: asingasviki 60 mL / min / 1.73m²;
• Yakakomba itsvo kutadza kana itsvo kutadza: kana isingasviki gumi nemashanu mL / min / 1.73m².

Zvinoenderana nezera, zvakajairwa GFR tsika dzinowanzo kuve:

• Pakati pemakore makumi maviri nemakumi maviri nepfumbamwe: 116 mL / min / 1.73m²;
• Pakati pemakore makumi matatu nemakumi matatu nepfumbamwe: 107 mL / min / 1.73m²;
• Pakati pemakore makumi mana nemakumi mana nepfumbamwe: 99 mL / min / 1.73m²;
• Pakati pemakore makumi mashanu nemapfumbamwe: 93 mL / min / 1.73m²;
• Pakati pemakore makumi matanhatu nemakumi matanhatu nemapfumbamwe: 85 mL / min / 1.73m²;
• Kubva pamakore makumi manomwe: 75 mL / min / 1.73m².

Maitiro acho anogona kusiyana zvichienderana neirabhoritari, zvisinei kana iyo GFR iri yakaderera pane yakajairwa kukosha kwezera, mukana wehosha yeitsvo unofungidzirwa, uchikurudzirwa nekuitwa kweimwe bvunzo kuitira kupedzisa kuongororwa. sekufungidzira bvunzo uye biopsy. Uye zvakare, zvichibva pahunhu hwakawanikwa neGFR, chiremba anogona kutarisa padanho rechirwere uye, nekudaro, kuratidza kurapwa kwakakodzera kwazvo.