Yakananga uye isina kunangana coomb kuyedza: kuti chii uye ndeyei

Zvemukati

• Maitirwo ebvunzo
• Zvinoreva mhedzisiro

Iyo coomb bvunzo rudzi rweyedzo yeropa inoongorora kuvepo kweanorwisa masoja anorwisa masero matsvuku eropa, zvichikonzera kuparadzwa kwavo uye pamwe zvichizotungamira pakuonekwa kwerudzi rweanemia inozivikanwa sehemolytic.

Kune maviri makuru marudzi ebvunzo iyi, ayo anosanganisira:

• Nongedzera Coombs Bvunzo: inoongorora zvakananga masero matsvuku eropa, kutarisa maantibhakitiriya akasunganidzwa nesero tsvuku reropa uye kuti maantibhakitiriya aya anobva muhutachiona hwemunhu here kana kuti akagamuchirwa nekuisirwa Muedzo uyu unowanzoitwa kuti uone autoimmune hemolytic anemias - Ona izvo zviratidzo zvinogona kuratidza hemolytic anemia;
• Zvisina kunangana Coombs bvunzo: inoongorora seramu yeropa, ichiratidza masoja ekudzivirira chirwere aripo, uye inowanzo kumbirwa mumamiriro ekuwedzerwa ropa, kuona kuti ropa richapihwa rinoenderana nemutori.

Pamusoro pekushaya ropa, bvunzo iyi inogona kubatsirawo kuziva zvimwe zvirwere zvinokanganisa masero eropa akadai seleukemia, lupus, mononucleosis uye fetal erythroblastosis, inozivikanwawo sehemolytic chirwere checheche achangozvarwa, pamwe nekuratidza njodzi yekuwedzerwa ropa. Dzidza zvakawanda nezve fetus erythroblastosis.

Maitirwo ebvunzo

Iyo Coombs bvunzo inoitwa kubva kune yeropa sampuro, iyo inofanirwa kuunganidzwa mune yekiriniki yekuongorora rabhoritari. Ropa rakaunganidzwa rinotumirwa ku laboratori, uko kunoitwa kwakananga kana zvisina kunangana kuongororwa kwaCombomb, zvichienderana nechinangwa.

Mukuyedza kwakananga kweCombombs, iyo Coombs reagent inowedzerwa muropa remurwere, ichibvumidza kuona kwema antibodies anogona kunge akabatana nemasero matsvuku eropa. Mukuyedza kusinganzwisisike kweCombombs, iro ropa rinounganidzwa uye centrifuged, richipatsanura masero matsvuku eropa kubva kune serum, iyo ine ma antibodies. Kune iyo serum, masero matsvuku 'pre-akanyorwa' nema antibodies anowedzerwa kuitira kutarisa kana paine autoantibodies aripo muserum uye, nekudaro, muropa remurwere.

Kuita iyo Coombs bvunzo, hapana gadziriro inodiwa, asi mimwe mishonga inogona kukanganisa mhedzisiro, saka zvakakosha kuzivisa chiremba nezve mashandisiro ayo kuti nhungamiro inogona kupihwa pakumiswa kwayo.

Zvinoreva mhedzisiro

Mhedzisiro yeiyo Coombs bvunzo haina kunaka kana pasina antibody iyo inokonzeresa kuparara kwemaglobhu matsvuku, ndosaka ichionekwa seyakajairwa mhedzisiro.

Nekudaro, kana mhedzisiro yacho iri yakanaka, zvinoreva kuti pane antibody muropa uye, nekudaro, kana mhedzisiro yacho iri yakanaka mune yakananga Coombs bvunzo zvinoreva kuti munhu angave nechirwere chakadai se:

• Autoimmune hemolytic kupererwa neropa;
• Kubatwa ne Mycoplasma sp.;
• Njovhera;
• Leukemia;
• Lupus erythematosus;
• Mononucleosis.

Panyaya yekunanga zvisina kunangana kweCombombs, mhedzisiro yacho inoreva kuti munhu ane antibody inogona kukonzeresa kugwamba paanogamuchira imwe mhando yeropa uye, nekudaro, zvinofanirwa kuve nekuchenjerera kana uchiwedzera kuwedzerwa ropa.

Chero zvazvingaitika, zvinogara zvichikosha kuti mhedzisiro yacho iongororwe nachiremba akaikumbira, nekuti imwe nhoroondo yemunhu inogona kuchinja mhedzisiro.