Truvada (emtricitabine uye tenofovir disoproxil fumarate)

Zvemukati

• Chii chinonzi Truvada?
• Kubudirira
• Truvada generic
• Truvada mhedzisiro
• Zvimwe zvakajairika mhedzisiro
• Yakakomba mhedzisiro
• Rutivi mhedzisiro mhedzisiro
• Yakareba-nguva mhedzisiro
• Immune kudzokorodza chirwere
• Lactic acidosis
• Kuwedzera kwehutachiona hwehutachiona hwehepatitis B
• Mapundu eganda
• Kurera huremu kana kuwana
• Truvada muyero
• Mafomu emishonga uye simba
• Chipimo chemushonga weHIV
• Chipimo chemushonga weHIV (PrEP)
• Ko kana ndikapotsa dosi? Ndinofanira kutora dhivhosi here?
• Kuedzwa usati watanga Truvada
• Truvada inoshandisa
• Truvada yeHIV
• Kubudirira pakurapa HIV
• Truvada ye pre-exposure prophylaxis (PrEP)
• Kubudirira kwekudzivirira HIV (PrEP)
• Truvada shandisa nemimwe mishonga
• Shandisa nemimwe mishonga yekurapa HIV
• Truvada naTivicay
• Truvada uye Isentress
• Truvada naKaletra
• Kwete kushandiswa nemimwe mishonga yeHIV PrEP
• Truvada uye doro
• Truvada kudyidzana
• Truvada nemimwe mishonga
• Zvinodhaka zvinokwanisa kuyanana neTruvada
• Truvada uye grapefruit
• Dzimwe nzira kuTruvada
• Dzimwe nzira dzekurapa HIV
• Dzimwe nzira dzeHIV pre-exposure prophylaxis (PrEP)
• Truvada vs. Descovy
• Zvinoshandiswa
• Zvishandiso
• Mafomu uye manejimendi
• Side migumisiro uye njodzi
• Zvimwe zvakajairika mhedzisiro
• Yakakomba mhedzisiro
• Kubudirira
• Mariro
• Maitiro ekutora Truvada
• Nguva
• Kutora Truvada nechikafu
• Truvada inogona kupwanywa here?
• Mashandiro anoita Truvada
• Zvinotora nguva yakareba sei kuti zvishande?
• Truvada matanho
• Zvimwe zvekuchengetedza
• Truvada kudarika
• Ovhadhozi zviratidzo
• Zvekuita kana ovhadhozi
• Truvada uye nhumbu
• Truvada uye kuyamwisa
• Mibvunzo yakajairika yeTruvada
• Truvada inogona kukonzera chirwere cheshuga here?
• Truvada inogona kushandiswa kurapa herpes?
• Ndinogona here kushandisa Tylenol pandinotora Truvada?
• Kupera kweTruvada

Chii chinonzi Truvada?

Truvada izita rezita rekushandisa mishonga yekurapa hutachiona hweHIV. Inoshandiswa zvakare mukudzivirira hutachiona hweHIV muvanhu vane njodzi huru yekubatira HIV. Uku kushandiswa, uko kurapwa kunopihwa munhu asati aonekwa neHIV, kunonzi pre-exposure prophylaxis (PrEP).

Truvada ine mishonga miviri mupiritsi imwe: emtricitabine uye tenofovir disoproxil fumarate. Ose madhiragi anoiswa se nucleoside reverse transcriptase inhibitors (NRTIs). Iyi mishonga inorwisa hutachiona, iyo inoshandiswa kurapa hutachiona kubva kumavirusi. Iyi chaiyo antiviral mishonga inorwisa HIV (human immunodeficiency virus).

Truvada inouya sehwendefa raunotora nemuromo kamwe zuva nezuva.

Kubudirira

Kuti uwane ruzivo nezve kushanda kweTruvada, ona iyo "Truvada inoshandisa" chikamu pazasi.

Truvada generic

Truvada inowanikwa chete sezita-zita mushonga. Haisi ikozvino inowanikwa mune generic fomu.

Truvada ine maviri anoshanda zvinodhaka zvinoshandiswa: emtricitabine uye tenofovir disoproxil fumarate.

Truvada mhedzisiro

Truvada inogona kukonzera manyoro kana zvakakomba mhedzisiro. Iri rinotevera runyorwa rine mamwe akakosha mhedzisiro mhedzisiro anogona kuitika uchitora Truvada. Rondedzero iyi haisanganisi zvese zvinokanganisa mhedzisiro.

Kuti uwane rumwe ruzivo nezve zvinogona kuitika mhedzisiro yeTruvada, kana matipi ekuti ungagadzirise sei zvinokanganisa mhedzisiro, taura nachiremba wako kana wemishonga.

Zvimwe zvakajairika mhedzisiro

Iyo inowanzoitika mhedzisiro mhedzisiro yeTruvada inosanganisira:

• kuneta
• kusvotwa
• kurutsa
• manyoka
• dzungu
• mweya wekufema
• sinus chirwere
• mapundu
• musoro
• kushaya hope (kunetseka kurara)
• kurwadziwa kwepfupa
• huro inorwadza
• cholesterol yakawanda

Mazhinji emhedzisiro iyi anogona kuenda mukati memazuva mashoma kana mavhiki mashoma. Kana vakanyanya kuomarara kana vasingaendi, taura nachiremba wako kana wemishonga.

Yakakomba mhedzisiro

• Zvinetso zvechiropa. Zviratidzo zvezvinetso zveropa zvinogona kusanganisira:
  • kurwadziwa kana kuzvimba mudumbu rako (mudumbu)
  • kusvotwa
  • kurutsa
  • kuneta
  • yero yeganda rako uye nekuchena kwemeso ako
• Kushungurudzika. Zviratidzo zvinogona kusanganisira:
  • kunzwa kusuruvara kana kudzikira
  • kuderedzwa kufarira zviitiko zvawaimbofarira
  • kurara zvakanyanya kana kushoma
  • kuneta kana kupera simba
• Bone kurasikirwa
• Zvinetso zveitsvo
• Immune kudzokorodza chirwere *
• Lactic acidosis *
• Kuwedzera kwehutachiona hwehepatitis B *

Rutivi mhedzisiro mhedzisiro

Unogona kushamisika kuti kangani mamwe maratidziro anoitika nemushonga uyu. Heano mamwe marondedzero pane mamwe maratidziro echirwere ichi chingakonzeresa.

Yakareba-nguva mhedzisiro

Kushandiswa kwenguva yakareba kweTruvada kunogona kuwedzera njodzi yako yekurasikirwa nemapfupa uye matambudziko eitsvo.

Kana ichishandiswa kurapa HIV, Truvada inoshandiswa mukubatana pamwe nemamwe maantiviral zvinodhaka. Zvichienderana nekuti ndeapi mamwe madhiragi anotorwa neTruvada, mamwe marefu-mhedzisiro mhedzisiro anogona kuitika.

Bone kurasikirwa

Truvada inogona kukonzeresa kurasikirwa kwefupa muvakuru, uye kudzikisa kukura kwefupa muvana. Kunyangwe zviratidzo zvekutanga zvekurasikirwa kwemapfupa zvisingawanzoitika, zvimwe zviratidzo zvinogona kusanganisira:

• kudzikamisa matadza
• simba risina simba
• nzara, nzara dzinopwanyika

Kana iwe ukatora Truvada, chiremba wako anogona kuita bvunzo kuti atarise kurasikirwa kwepfupa. Ivo vanogona zvakare kukurudzira kuti iwe utore vhitamini D uye calcium zvinowedzera kuti ubatsire kudzivirira kurasikirwa kwepfupa.

Kuti uwane kuti kangani kurasikirwa kwemapfupa kwakaitika muzvidzidzo zvekiriniki, ona ruzivo rwekutsanangura kwaTruvada.

Zvinetso zveitsvo

Mune vamwe vanhu, Truvada inogona kukonzera kana kuwedzera matambudziko eitsvo. Zvisinei, njodzi inoratidzika kunge yakaderera. Kuti uzive kuti kangani divi mhedzisiro iyi yakaitika muzvidzidzo zvekiriniki, ona ruzivo rwekuraira kwaTruvada.

Chiremba wako anozoita ongororo yeropa kuti aongorore itsvo yako usati waita uye panguva yekurapwa kwako naTruvada. Kana itsvo dzako dzisiri kushanda nemazvo, chiremba wako anogona kuchinja chipimo chemushonga cheTruvada. Kana uine zvinetso zvakakomba zveitsvo, unogona kusakwanisa kutora Truvada.

Zviratidzo zvezvinetso zveitsvo zvinogona kusanganisira:

• pfupa kana kurwadziwa kwemhasuru
• kushaya simba
• kuneta
• kusvotwa
• kurutsa
• yakaderera weti kubuda

Kana iyi mhedzisiro ikaitika kana kuve yakaoma, chiremba wako anogona kukurudzira kuti umire kutora Truvada uye chinja kune kumwe kurapwa.

Immune kudzokorodza chirwere

Kurapa kweHIV neTruvada kana mishonga yakafanana kunogona kukonzera kukurumidza kukurumidza mukuita kwema immune system (ayo anorwisa chirwere).

Mune zvimwe zviitiko, izvi zvinogona kukonzera kuti muviri wako upindure kuzvirwere zvawave nazvo kare. Izvi zvinogona kuita kuti zviite kunge une hutachiona hutsva, asi zvinongova zvemuviri wako wakasimbiswa immune system inobata kune hutachiona hwekare.

Iyi mamiriro anonzi immune reconstitution syndrome. Inodanwawo kuti immune reconstitution inflammatory syndrome (IRIS), nekuti muviri wako unowanzo pindura kuhutachiona nehupamhi hwehutachiona.

Mienzaniso yezvirwere zvinogona "kuonekazve" nemamiriro aya zvinosanganisira tibhii, mabayo, uye hutachiona hutachiona. Kana hutachiona uhu hukadzokororwazve, chiremba wako anogona kukupa mishonga inorwisa mabhakitiriya kana yekurapa.

Kuti uzive kuti kangani ichi immune reconstitution syndrome chakaitika muzvidzidzo zvekiriniki, ona ruzivo rwekutsanangura rweTruvada. Kana iwe uine mibvunzo kana kunetsekana nezve izvi zvinogona kuita mhedzisiro, taura nachiremba wako kana wemishonga

Lactic acidosis

Kune mimwe mishumo ye lactic acidosis muvanhu vanotora Truvada. Lactic acidosis ndeyekuwedzera kweasidhi mumuviri iyo inogona kutyisidzira hupenyu. Kana iwe ukaita zviratidzo zve lactic acidosis, chiremba wako anogona kukurudzira kumisa kurapwa kwako naTruvada.

Zviratidzo zveactic acidosis zvinogona kusanganisira:

• tsandanyama
• kuvhiringidzika
• mweya unonhuwirira muchero
• kushaya simba
• kuneta
• kunetseka kufema

Kuti uzive kuti kangani lactic acidosis yakaitika muzvidzidzo zvekiriniki, ona ruzivo rwekuraira kwaTruvada. Kana iwe uine mibvunzo kana kunetsekana nezve izvi zvinogona kuitika mhedzisiro, taura nachiremba wako kana wemishonga.

Kuwedzera kwehutachiona hwehutachiona hwehepatitis B

Kuwedzera kwehutachiona hwehutachiona hwehutachiona B kunogona kuitika kune vanhu vane hepatitis B vanorega kutora Truvada. Kana iwe uine hepatitis B uye worega kutora Truvada, chiremba wako anozoita kuongororwa kweropa nguva nenguva kuti atarise chiropa chako kwemwedzi yakati wandei mushure mekumisa mushonga.

Zviratidzo zvehutachiona hwehepatitis B zvinogona kusanganisira:

• kurwadziwa kana kuzvimba mudumbu mako
• kusvotwa
• kurutsa
• kuneta
• yero yeganda rako uye nekuchena kwemeso ako

Kuti uwane kuti kuwanda kwehutachiona hwehepatitis B kwakaitika kangani muzvidzidzo zvekiriniki, ona ruzivo rwekutsanangura kwaTruvada. Kana iwe uine mibvunzo kana kunetsekana nezve izvi zvinogona kuita mhedzisiro, taura nachiremba wako kana wemishonga.

Mapundu eganda

Rash inowanzoitika mhedzisiro yeTruvada. Iyi divi mhedzisiro inogona kuenda nekuenderera mberi nekushandisa kwechirwere.

Kuti uone kuti kangani kuputika kwakaitika muzvidzidzo zvekiriniki, ona ruzivo rwekutsanangura kwaTruvada. Kana iwe uine mibvunzo kana kunetsekana nezve izvi zvinogona kuitika mhedzisiro, taura nachiremba wako kana wemishonga.

Kurera huremu kana kuwana

Kurera huremu kwakaitika muvanhu vanotora Truvada. Kuti uwane kuti kangani kurasikirwa kwekurema kwakaitika muzvidzidzo zvekiriniki, ona ruzivo rwekutsanangura kwaTruvada.

Kurera huremu hakuna kumbotaurwa muzvidzidzo zveTruvada.

Kana iwe uine mibvunzo kana kunetsekana nezve imwe yeaya anogona mhedzisiro, taura nachiremba wako kana wemishonga.

Truvada muyero

Ruzivo runotevera runotsanangura madosi ayo anowanzo shandiswa kana kukurudzirwa. Zvisinei, iva nechokwadi chekutora muyero uyo chiremba wako anokuraira iwe. Chiremba wako achasarudza yakanakisa dosi kuti ienderane nezvaunoda.

Mafomu emishonga uye simba

Truvada inouya sehwendefa remuromo rine mishonga miviri mupiritsi imwe neimwe: emtricitabine uye tenofovir disoproxil fumarate. Iyo inouya nemasimba mana:

• 100 mg emtricitabine / 150 mg tenofovir disoproxil fumarate
• 133 mg emtricitabine / 200 mg tenofovir disoproxil fumarate
• 167 mg emtricitabine / 250 mg tenofovir disoproxil fumarate
• 200 mg emtricitabine / 300 mg tenofovir disoproxil fumarate

Chipimo chemushonga weHIV

Muyero weTruvada zvinoenderana nehuremu hwemunhu. Aya ndiwo chaiwo madosi:

• Zvevakuru kana vana vanorema 35 kg (77 lbs) kana kudarika: Hwendefa rimwe chete, 200 mg emtricitabine / 300 mg tenofovir disoproxil fumarate, inotorwa kamwe chete pazuva.
• Kune vana vanorema 28 kusvika 34 kg (62 kusvika 75 lb): Hwendefa rimwe chete, 167 mg emtricitabine / 250 mg tenofovir disoproxil fumarate, inotorwa kamwe chete zuva nezuva.
• Kune vana vanorema 22 kusvika 27 kg (48 kusvika 59 lb): Hwendefa rimwe chete, 133 mg emtricitabine / 200 mg tenofovir disoproxil fumarate, inotorwa kamwe chete zuva nezuva.
• Kune vana vanorema 17 kusvika 21 kg (37 kusvika 46 lb): Hwendefa rimwe chete, 100 mg emtricitabine / 150 mg tenofovir disoproxil fumarate, inotorwa kamwe chete zuva nezuva.

Kune vanhu vane chirwere cheitsvo: Chiremba wako anogona kuchinja kuti unotora kangani Truvada.

• Kune chirwere cheitsvo chinyoro, hapana shanduko yedosi inodiwa.
• Kune chirwere cheitsvo chine mwero, unogona kutora Truvada mazuva ese.
• Kune chirwere chakakomba cheitsvo, kusanganisira kana iwe uri pane dialysis, unogona kusakwanisa kutora Truvada.

Chipimo chemushonga weHIV (PrEP)

Kune vanhu vakuru kana vachiri kuyaruka vanorema 35 kg (77 lbs) kana kupfuura, piritsi rimwe re200 mg emtricitabine / 300 mg tenofovir disoproxil fumarate inotorwa kamwe chete zuva nezuva. (Mugadziri haape muyero wevanhu vanorema isingasvike 35 kg [77 lbs]).

Kana uine chirwere cheitsvo, unogona kusakwanisa kutora Truvada ye pre-exposure prophylaxis (PrEP).

Ko kana ndikapotsa dosi? Ndinofanira kutora dhivhosi here?

Kana iwe ukarasikirwa neiyo dose, tora iyo nekukurumidza sezvaunoyeuka. Asi kana ingangoita nguva yedosi yako inotevera, ingotora iyo imwe chete dose. Usapeta kaviri muyero kuti ubate. Kutora miviri miviri panguva imwe chete kunogona kuwedzera njodzi yako yemigumisiro yakakomba.

Kana iwe uchifunga kuti wakanganisa netsaona maviri kana anopfuura madhizaini muzuva rimwe chete, fonera chiremba wako. Vanogona kukurudzira kurapwa kwechero zviratidzo zvaungave uine, kana kurapwa kwekudzivirira mhedzisiro kubva mukuitika.

Kuedzwa usati watanga Truvada

Usati watanga Truvada, chiremba wako achaita kumwe kuongorora kweropa. Iyi bvunzo ichaongorora:

• hepatitis B hutachiona hutachiona
• itsvo uye chiropa chinoshanda matambudziko
• kuvapo kwehutachiona hweHIV (yePrEP chete)
• HIV uye immune system masero eropa kuverenga (kweHIV kurapwa chete)

Chiremba wako achaita izvi kuongororwa ropa uye zvimwe usati watanga kutora Truvada, uye nguva nenguva panguva yekurapwa kwako nemushonga.

Truvada inoshandisa

Chikafu neDrug Administration (FDA) inobvumidza mishonga yemishonga yakadai seTruvada kurapa mamwe mamiriro.

Truvada FDA-inogamuchirwa pakurapa hutachiona hweHIV, uye kudzivirira hutachiona hweHIV muvanhu vane njodzi huru yekuwana Mukondombera. Uku kushandiswa kwechipiri, uko kurapwa kunopihwa munhu asati aonekwa nehutachiona hweHIV, kunonzi pre-exposure prophylaxis (PrEP).

Truvada yeHIV

Truvada inobvumidzwa kurapa hutachiona hweHIV mune vese vakuru nevana. HIV hutachiona hunoshayisa simba immune system. Pasina kurapwa, hutachiona hweHIV hunogona kukura kuva AIDS. Mune zvimwe zviitiko, Truvada inogona kushandiswa kurapa vanhu vakaedza imwe nzira yekurapwa kweHIV isina kuvashandira.

Truvada inoonekwa se "musana" mushonga. Izvi zvinoreva kuti ndeimwe yemishonga iyo chirongwa chekurapa hutachiwana chakavakirwa pairi. Mimwe mishonga inotorwa pamwe chete nemushonga wemusana.

Truvada inogara ichishandiswa pamwe neumwe mumwe mushonga wehutachiona pakurapa HIV. Mienzaniso yemishonga inorwisa hutachiona inogona kushandiswa neTruvada kurapa HIV inosanganisira:

• Isentress (raltegravir)
• Tivicay (dolutegravir)
• Evotaz (atazanavir uye cobicistat)
• Prezcobix (darunavir uye cobicistat)
• Kaletra (lopinavir uye ritonavir)
• Prezista (darunavir)
• Reyataz (atazanavir)
• Norvir (ritonavir)

Kubudirira pakurapa HIV

Zvinoenderana nemazano ekurapa, Truvada, pamwe chete nemumwe mushonga unodzivirira hutachiona, inoonekwa sechisarudzo chekutanga chemunhu ari kutanga kurapwa kweHIV.

Chekutanga-kusarudza mishonga yeHIV mishonga iri:

• inoshanda pakudzikisa hutachiona huwandu
• vane mashoma mhedzisiro pane dzimwe sarudzo
• nyore kushandisa

Mashandiro anoita Truvada kumunhu wega wega zvinoenderana nezvinhu zvakawanda. Izvi zvinhu zvinosanganisira:

• hunhu hwehutachiona hweHIV
• mamwe mamiriro ehutano avanawo
• kuti vanonamira zvakadii pakurapwa kwavo

Kuti uwane ruzivo rwekuti mushonga uyu wakaitwa sei muzvidzidzo zvekiriniki, ona ruzivo rwekuraira kwaTruvada.

Truvada ye pre-exposure prophylaxis (PrEP)

Truvada ndiyo yega kurapwa-yakatenderwa FDA yekurapa pre-exposure prophylaxis (PrEP). Ndiwo chete mushonga wePrEP unokurudzirwa neCentre for Disease Control and Prevention (CDC).

Truvada inobvumidzwa kudzivirira Mukondombera muvakuru nevechiri kuyaruka vane njodzi huru yekuwana Mukondombera. Vanhu vane njodzi huru yekubatira HIV vanosanganisira avo vanoti:

• iva nemumwe wako wepabonde ane hutachiona hweHIV
• vanoita bonde munzvimbo ine hutachiona hweHIV uye vane zvimwe zvinenjodzi, senge:
  • kusashandisa kondomu
  • kugara mutirongo kana mujeri
  • kuva nedoro kana zvinodhaka
  • kuva nechirwere chepabonde
  • kuchinjana bonde nemari, zvinodhaka, chikafu, kana pekugara

Kubudirira kwekudzivirira HIV (PrEP)

Truvada ndiyo chete kurapwa kunotenderwa neKudya neDrug Administration (FDA) yePrEP. Ndiwo chete mushonga wePrEP unokurudzirwa neCentre for Disease Control and Prevention (CDC). Izvo zvakawanikwa zvichibudirira mukuderedza njodzi yekutapukirwa neHIV.

Kuti uwane ruzivo rwekuti mushonga uyu wakaitwa sei muzvidzidzo zvekiriniki, tarisa ruzivo rweTruvada uye ichi chidzidzo.

Truvada shandisa nemimwe mishonga

Truvada inoshandiswa pakurapa hutachiona hweHIV. Inoshandiswa zvakare mukudzivirira hutachiona hweHIV muvanhu vane njodzi huru yekubatira HIV. Uku kushandiswa kwechipiri kunonzi pre-exposure prophylaxis (PrEP).

Shandisa nemimwe mishonga yekurapa HIV

Kana ichishandiswa kurapa HIV, Truvada inoshandiswa mukubatana pamwe nemamwe maantiviral zvinodhaka.

Zvinoenderana nemazano ekurapwa kweHIV, Truvada inosanganisirwa nemumwe mushonga weantiviral seTivicay (dolutegravir) kana Isentress (raltegravir) inoonekwa senzira yekutanga-sarudzo painotanga kurapwa kweHIV. Mune zvimwe zviitiko, Truvada inogona kushandiswa kurapa vanhu vakaedza imwe nzira yekurapwa kweHIV isina kuvashandira.

Chekutanga-kusarudza mishonga yeHIV mishonga ndeiyi:

• inoshanda mukuderedza hutachiona
• vane mashoma mhedzisiro pane dzimwe sarudzo
• nyore kushandisa

Truvada naTivicay

Tivicay (dolutegravir) rudzi rwemushonga unonzi HIV integrase inhibitor. Tivicay inowanzo shandiswa pamwe chete naTruvada pakurapa HIV.

Zvinoenderana nemazano ekurapa, kutora Truvada neTivicay sarudzo yekutanga kune vanhu vari kutanga kurapwa kweHIV.

Truvada uye Isentress

Isentress (raltegravir) rudzi rwemushonga unonzi HIV integrase inhibitor. Isentress inowanzo shandiswa pamwe chete neTruvada yekurapa HIV.

Zvinoenderana nemazano ekurapwa kweHIV, kutora Truvada neIsentress ndiyo sarudzo yekutanga kune vanhu vari kutanga kurapwa kweHIV.

Truvada naKaletra

Kaletra ine mishonga miviri mupiritsi imwe: lopinavir uye ritonavir. Mishonga iyi iri muKaletra inorondedzerwa seprotease inhibitors.

Kaletra dzimwe nguva inosanganiswa neTruvada kurapa HIV. Kunyangwe hazvo mubatanidzwa uyu uchishanda pakurapa HIV, nhungamiro yekurapa haikurudziri senzira yekutanga-sarudzo kuvanhu vazhinji vanotanga kurapwa kweHIV Imhaka yekuti kusanganiswa uku kune njodzi yakakwira yemhedzisiro pane dzimwe sarudzo.

Kwete kushandiswa nemimwe mishonga yeHIV PrEP

Truvada inoshandiswa yoga kana ichinge yatemerwa pre-exposure prophylaxis (PrEP). Haisi kushandiswa nemimwe mishonga.

Truvada uye doro

Kunwa doro uchitora Truvada kunogona kuwedzera njodzi yako yemimwe mhedzisiro, senge:

• kusvotwa
• kurutsa
• manyoka
• musoro

Kunwa doro rakawandisa uye kutora Truvada kunogona zvakare kuwedzera njodzi yako yechiropa kana itsvo matambudziko.

Kana iwe ukatora Truvada, taura nachiremba wako nezvekuti kunwa doro kwakachengeteka kwauri here.

Truvada kudyidzana

Truvada inogona kudyidzana nemimwe mishonga yakati wandei. Iyo inogona zvakare kudyidzana nezvimwe zvinowedzera, pamwe neiyo grapefruit muto.

Kukurukurirana kwakasiyana kunogona kukonzera mhedzisiro. Semuenzaniso, vamwe vanogona kukanganisa mashandiro anoita mushonga, asi mamwe anogona kukonzera kuwedzera mhedzisiro.

Truvada nemimwe mishonga

Pazasi pane runyorwa rwemishonga inogona kusangana neTruvada. Urongwa urwu hauna mishonga yose inogona kuwirirana neTruvada.

Usati watora Truvada, ita shuwa yekuudza chiremba wako uye wemishonga nezvese zvinyorwe, pamusoro-pekutengesa, uye mimwe mishonga yaunotora. Vaudzewo nezve chero mavitamini, mahebhu, uye zvinowedzera zvaunoshandisa. Kugovera ruzivo urwu kunogona kubatsira iwe kudzivirira kusangana kunogona kuitika.

Kana iwe uine mibvunzo nezve kudyidzana kwezvinodhaka zvinogona kukukanganisa, bvunza chiremba wako kana wemishonga.

Zvinodhaka zvinokwanisa kuyanana neTruvada

Pazasi pane mienzaniso yemishonga inogona kusangana neTruvada. Urongwa urwu hauna mishonga yose inogona kuwirirana neTruvada.

• Zvinodhaka zvinokanganisa kushanda kwetsvo. Truvada inobviswa mumuviri wako neitsvo dzako. Kutora Truvada nemimwe mishonga inobviswa neitsvo dzako, kana zvinodhaka zvinogona kukuvadza itsvo dzako, zvinogona kuwedzera mwero weTruvada mumuviri wako uye kuwedzera njodzi yako yemhedzisiro. Mienzaniso yemishonga inobviswa neitsvo dzako kana iyo inogona kukuvadza itsvo dzako inosanganisira:
  • acyclovir (Zovirax)
  • adefovir (Hepsera)
  • asipurini
  • cidofovir
  • diclofenac (Cambia, Voltaren, Zorvolex)
  • ganciclovir (Cytovene)
  • gentamicin
  • ibuprofen (Motrin)
  • naproxen (Aleve)
  • valacyclovir (Valtrex)
  • Valganciclovir (Valcyte)
• Atazanavir. Kutora Truvada neatazanavir (Reyataz), unova mumwe mushonga weHIV, kunogona kudzikisa huwandu hweatazanavir mumuviri wako. Izvi zvinogona kuita kuti atazanavir isanyanya kushanda.
• Didanosine. Kutora Truvada nedadanosine (Videx EC) kunogona kuwedzera madanosine mwero mumuviri wako uye kuwedzera njodzi yako yemhedzisiro yedhaganosi.
• Epclusa. Mushonga unorapa hepatitis C, Epclusa ine mishonga miviri mupiritsi imwe: sofosbuvir uye velpatasvir.Kutora Epclusa naTruvada kunogona kuwedzera mwero wemuviri wako we tenofovir, chimwe chezvinhu zveTruvada. Izvi zvinogona kuwedzera njodzi yako yemhedzisiro kubva kune tenofovir.
• Harvoni. Mushonga unorapa hepatitis C, Harvoni ine mishonga miviri mupiritsi imwe: sofosbuvir uye ledipasvir. Kutora Harvoni naTruvada kunogona kuwedzera mwero wemuviri wako we tenofovir, chimwe chezvinhu zveTruvada. Izvi zvinogona kuwedzera njodzi yako yemhedzisiro kubva kune tenofovir.
• Kaletra. Kaletra, mumwe mushonga weHIV, une mishonga miviri mupiritsi imwe: lopinavir uye ritonavir. Kutora Kaletra neTruvada kunogona kuwedzera mwero wemuviri wako we tenofovir, chimwe chezvinhu zveTruvada. Izvi zvinogona kuwedzera njodzi yako yemhedzisiro kubva ku tenefovir.

Truvada uye grapefruit

Kunwa muto wemazambiringa paunenge uchitora Truvada kunogona kuwedzera mwero wemuviri wako wegumiofovir, chimwe chezvigadzirwa muTruvada. Izvi zvinogona kuwedzera njodzi yako yemhedzisiro kubva kune tenofovir. Kana iwe uri kutora Truvada, usanwe muto wemazambiringa.

Iko hakuna kunge kwave nezvidzidzo pamhedzisiro yekudya grapefruit uchitora Truvada. Nekudaro, inogona kunge iri zano rakanaka rekurega kudya huwandu hwakawanda hwe grapefruit kuti zvidzivise zvinogona kuwedzera mhedzisiro.

Dzimwe nzira kuTruvada

Truvada ine mishonga miviri mupiritsi imwe: emtricitabine uye tenofovir disoproxil fumarate. Iyi mishonga inorondedzerwa se nucleoside reverse transcriptase inhibitors (NRTIs). Truvada inoshandiswa kurapa nekudzivirira hutachiona hweHIV.

Kune mimwe mishonga yakawanda inoshandiswa pakurapa HIV. Zvimwe zvinogona kunge zvakakukodzera iwe kupfuura vamwe. Taura nachiremba wako kuti udzidze zvakawanda nezvemimwe mishonga inogona kukushandira zvakanaka.

Dzimwe nzira dzekurapa HIV

Kana yashandiswa kurapa HIV, Truvada inosanganiswa nemimwe mishonga yeHIV antiviral. Musanganiswa weTruvada wakajairika ndiTruvada pamwe neIsentress (raltegravir), uye Truvada pamwe neTivicay (dolutegravir). Izvi zvinoonekwa senzira dzekutanga dzekurapa vanhu vari kutanga kurapwa kweHIV.

Mienzaniso yeimwe yekutanga-sarudzo HIV mishonga inosanganiswa iyo inogona kushandiswa kurapa HIV inosanganisira:

• Biktarvy (bictegravir, emtricitabine, tenofovir alafenamide)
• Genvoya (elvitegravir, cobicistat, tenofovir alafenamide, emtricitabine)
• Stribild (elvitegravir, cobicistat, tenofovir disoproxil fumarate, emtricitabine)
• Isentress (raltegravir) pamwe Descovy (tenofovir alafenamide uye emtricitabine)
• Isentress (raltegravir) pamwe Viread (tenofovir disoproxil fumarate) uye lamivudine
• Tivicay (dolutegravir) pamwe Descovy (tenofovir alafenamide uye emtricitabine)
• Tivicay (dolutegravir) pamwe Viread (tenofovir disoproxil fumarate) uye lamivudine
• Triumeq (dolutegravir, abacavir, lamivudine)

Chekutanga-kusarudza mishonga yeHIV mishonga iyo:

• batsira kudzikisa hutachiona
• vane mashoma mhedzisiro pane dzimwe sarudzo
• zviri nyore kushandisa

Kune mimwe mishonga yakawanda pamwe nekubatanidzwa kwezvinodhaka zvinoshandiswa kurapa HIV mune mamwe mamiriro ezvinhu, asi izvi zvinongoshandiswa chete kana mubatanidzwa wekutanga wemishonga usingashandiswe.

Dzimwe nzira dzeHIV pre-exposure prophylaxis (PrEP)

Truvada ndiyo yega kurapwa-yakatenderwa FDA yePrEP. Ndiwo chete mushonga wePrEP unokurudzirwa neCentre for Disease Control and Prevention (CDC). Parizvino, hapana dzimwe nzira dzeTruvada dzePrEP.

Truvada vs. Descovy

Unogona kushamisika kuti Truvada inofananidzwa sei nemimwe mishonga inorayirwa kushandiswa kwakafanana. Pano tinotarisa kuti Truvada naDescovy vakafanana uye vakasiyana sei.

Zvinoshandiswa

Truvada ine mishonga miviri mupiritsi imwe: emtricitabine uye tenofovir disoproxil fumarate. Descovy zvakare ine mishonga miviri mupiritsi imwe: emtricitabine uye tenofovir alafenamide.

Mishonga yese iri miviri ine mushonga tenofovir, asi nenzira dzakasiyana. Truvada ine tenofovir disoproxil fumarate uye Descovy ine tenofovir alafenamide. Iyi mishonga yakafanana, asi ine mhedzisiro yakati siyanei mumuviri.

Zvishandiso

Truvada naDescovy vese vari vaviri-vanobvumidzwa FDA kurapa hutachiona hweHIV kana ikashandiswa pamwe chete nemimwe mishonga yekudzivirira hutachiona.

Truvada inobvumidzwawo kudzivirira Mukondombera mune vanhu vane njodzi huru yekubatira HIV. Izvi zvinonzi pre-exposure prophylaxis (PrEP).

Mafomu uye manejimendi

Truvada naDescovy vese vanouya semapiritsi emuromo anotorwa kamwe chete zuva nezuva.

Side migumisiro uye njodzi

Truvada naDescovy zvakafanana zvinodhaka uye zvinokonzeresa zvakafanana uye zvakakomba mhedzisiro.

Zvimwe zvakajairika mhedzisiro

Mienzaniso yezvakawanda zvinowanzoitika mhedzisiro yeTruvada uye Descovy inosanganisira:

• manyoka
• musoro
• kuneta
• mweya wekufema
• huro inorwadza
• kurutsa
• mapundu

Yakakomba mhedzisiro

Mienzaniso yemhedzisiro mhedzisiro yakagovaniswa naTruvada naDescovy inosanganisira:

• kurasikirwa nefupa
• kukuvara kweitsvo
• kukuvara kwechiropa
• lactic acidosis
• immune reconstitution syndrome

Vaviri Truvada naDescovy vane yambiro yetsiva kubva kuDFA. Nyevero yebhokisi ndiyo yakasimba nzira yekunyevera iyo FDA inoda. Yambiro dzinotaura kuti mishonga iyi inogona kukonzera kuwedzera kwehutachiona hwehepatitis B kana kushandiswa kwemishonga kukamiswa.

Truvada naDescovy zvinogona kukonzera kurasikirwa kwemapfupa uye kukuvara kweitsvo. Nekudaro, Descovy inokonzeresa kushomeka kwepfupa kurasikirwa kupfuura Truvada. Descovy zvakare haina mikana yekukuvadza itsvo pane Truvada.

Kubudirira

Kubudirira kwaTruvada naDescovy hakuna kuenzaniswa zvakananga muzvidzidzo zvekiriniki. Nekudaro, fananidzo isina kunangana yakaratidza kuti Truvada naDescovy vanogona kushanda zvakaenzana pakurapa HIV.

Zvinoenderana nemazano ekurapa, Truvada kana Descovy inosanganiswa nemumwe mushonga weantiviral, senge Tivicay (dolutegravir) kana Isentress (raltegravir), inoonekwa senge sarudzo-yekutanga paunotanga kurapwa kweHIV.

Mariro

Mari yeTruvada kana Descovy inogona kusiyana zvichienderana nehurongwa hwako hwekurapa. Kuti uongorore mitengo inogona kuitika, shanyira GoodRx.com. Mutengo chaiwo wauchabhadhara chero mushonga unobva pane inishuwarenzi yako. nzvimbo yako, uye pharmacy yaunoshandisa.

Maitiro ekutora Truvada

Iwe unofanirwa kutora Truvada zvinoenderana nemirairo yechiremba wako.

Nguva

Truvada inofanirwa kutorwa kamwe chete zuva nezuva panguva inenge yakafanana zuva rega rega.

Kutora Truvada nechikafu

Truvada inogona kutorwa pamwe kana pasina chikafu. Kuitora nechikafu kunogona kubatsira kudzikisira chero kugumbuka kwedumbu kunogona kukonzerwa nemushonga.

Truvada inogona kupwanywa here?

Truvada piritsi yemuromo haifanire kupwanywa. Inofanira kumedzwa yakakwana.

Mashandiro anoita Truvada

Truvada ine mishonga miviri: emtricitabine uye tenofovir disoproxil fumarate. Iyi mishonga iri maviri nucleoside reverse transcriptase inhibitors (NRTIs).

Iyi mishonga inovhara enzyme inonzi reverse transcriptase iyo HIV inoda kuzviteedzera pachayo. Nekudzivirira enzyme iyi, Truvada inodzivirira hutachiona kubva mukukura nekuteedzera pachahwo. Nekudaro, huwandu hweHIV mumuviri wako unotanga kudzikira.

Zvinotora nguva yakareba sei kuti zvishande?

Iyo mishonga iri muTruvada inotanga kushanda ipapo ipapo kudzikisa huwandu hwehutachiona. Zvisinei, zvinogona kutora mwedzi mumwe kusvika kumatanhatu ekurapwa mazinga ako eHIV asati akadzika zvakakwana zvekuti haachaonekwe muropa rako. (Ichi ndicho chinangwa chekurapa. Kana hutachiwana hweHIV husingawanikwe, hauchakwanise kutapurirana kune mumwe munhu.)

Truvada matanho

Uyu mushonga une mabhokisi akanyeverwa kubva kuFood and Drug Administration (FDA). Nyevero yebhokisi ndiyo yambiro yakasimba iyo FDA inoda. Yambiro yebhokisi inozivisa vanachiremba nevarwere nezvezvinodhaka zvinogona kuva nenjodzi.

• Kuwedzera kwehutachiona hwehepatitis B (HBV) hutachiona: HBV hutachiona hunogona kuwedzera kune vanhu vane hutachiona hweHBV vorega kutora Truvada. Kana iwe uine HBV uye worega kutora Truvada, chiremba wako achaita kuongororwa kweropa kuti aongorore chiropa chako nguva nenguva kwemwedzi yakati wandei mushure mekumisa mushonga. Ungangoda kurapwa kwehutachiona hweHBV.
• Kuramba kuTruvada: Truvada haifanirwe kushandiswa pre-exposure prophylaxis (PrEP) muvanhu vatove neHIV nekuti izvi zvinogona kukonzera kuramba hutachiona kuTruvada. Kurwisa hutachiona kunoreva kuti HIV haichakwanise kurapwa neTruvada. Kana iwe uri kushandisa Truvada yePrEP, chiremba wako achaita kuongororwa kweropa kwehutachiona hweHIV usati watanga kurapwa uye kanokwana mwedzi mitatu yega panguva yekurapwa kwako.

Zvimwe zvekuchengetedza

Usati watora Truvada, taura nachiremba wako nezve nhoroondo yako yehutano. Truvada inogona kunge isingave yakakunakira iwe kana uine mamwe marapirwo kana zvimwe zvinhu zvinokanganisa hutano hwako. Izvi zvinosanganisira:

• Itsvo chirwere: Truvada inogona kukuvadza kushanda kweitsvo muvanhu vane chirwere cheitsvo. Kana iwe uine chirwere cheitsvo, ungangoda kutora Truvada zuva rega rega pane zuva nezuva. Kana iwe uine chirwere chakakomba cheitsvo, unogona kusakwanisa kutora Truvada.
• Chiropa chirwere: Truvada inogona kukonzera kukuvara kwechiropa. Kana iwe uine chirwere chechiropa, Truvada inogona kuita kuti mamiriro ako awedzere.
• Chirwere chepfupa: Truvada inogona kukonzera kurasikirwa kwepfupa. Kana iwe uine chirwere chepfupa, senge osteoporosis, unogona kuve nenjodzi yakawedzera yekutyoka kwepfupa kana iwe ukatora Truvada.

Ongorora: Kuti uwane rumwe ruzivo nezve zvingangoitika zvakaipa zveTruvada, ona iyo "Truvada mhedzisiro" chikamu pamusoro.

Truvada kudarika

Kutora zvakawandisa zvemushonga uyu kunogona kuwedzera njodzi yako yemhedzisiro.

Ovhadhozi zviratidzo

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

• mudumbu kugumbuka
• manyoka
• kurutsa
• kuneta
• musoro
• dzungu
• zviratidzo zvekukuvara kweitsvo, senge:
• pfupa kana kurwadziwa kwemhasuru
• kushaya simba
• kuneta
• kusvotwa
• kurutsa
• yakaderera weti kubuda
• zviratidzo zvekukuvara kwechiropa, senge:
• kurwadziwa kana kuzvimba mudumbu mako
• kusvotwa
• kurutsa
• kuneta
• yero yeganda kana kuchena kwemeso ako

Zvekuita kana ovhadhozi

Kana iwe uchifunga kuti watora zvakawandisa zvemushonga uyu, fonera chiremba wako kana kutsvaga nhungamiro kubva kuAmerican Association of Poison Control Centers pa800-222-1222 kana kuburikidza nechavo online chishandiso Asi kana zviratidzo zvako zvakakomba, fonera 911 kana kuenda kukamuri yepedyo yevanokurumidza ipapo.

Truvada uye nhumbu

Kutora Truvada panguva yekutanga trimester yepamuviri hakuite sekuwedzera mukana wekuremara kwekuzvarwa. Zvisinei, hapana ruzivo runowanikwa pamusoro pemigumisiro yeTruvada kana ikatorwa panguva yechipiri kana yechitatu trimesters, kana kana Truvada inowedzera njodzi yekuparara.

Mune zvidzidzo zvemhuka, Truvada yakanga isina zvinokuvadza pavana. Zvisinei, zvidzidzo zvemhuka hazviwanzo kuratidza kuti vanhu vaizopindura sei.

Kana iwe uri nepamuviri kana kuronga kuve nepamuviri, taura nachiremba wako usati watora Truvada. Kana iwe ukava nepamuviri uchitora Truvada, taura nachiremba wako ipapo.

Truvada uye kuyamwisa

Iyo mishonga iri muTruvada inopfuudzwa mumukaka wemukaka. Vanamai vari kutora Truvada havafanirwe kuyamwisa, nekuti mwana anoyamwiwa anogona kuve nemhedzisiro kubva kuTruvada.

Chimwe chikonzero chekusayamwisa ndechekuti HIV inogona kutapurirwa kumwana kuburikidza nemukaka wemukaka. MuUnited States, iyo Centers for Disease Control and Prevention (CDC) inokurudzira kuti vakadzi vane HIV vadzivise kuyamwa.

(World Health Organisation ichiri kukurudzira kuyamwisa vakadzi vane HIV munyika zhinji.)

Mibvunzo yakajairika yeTruvada

Heano mhinduro kumimwe inowanzo bvunzwa mibvunzo nezve Truvada.

Truvada inogona kukonzera chirwere cheshuga here?

Chirwere cheshuga hachisi mhedzisiro iyo yakataurwa muzvidzidzo zveTruvada. Nekudaro, itsvo mamiriro anonzi nephrogenic chirwere cheshuga insipidus yakaitika muvanhu vanotora Truvada. Nemamiriro aya, itsvo hadzishande nemazvo, uye munhu wacho anopfuudza huwandu hwakawanda weti. Izvi zvinogona kutungamira mukushaya mvura mumuviri.

Kana iwe uine ichi chiitiko uye chikave chakakomba, chiremba wako anogona kumisa kurapwa kwako naTruvada.

Zviratidzo zveinephrogenic chirwere cheshuga insipidus inogona kusanganisira:

• ganda rakaoma
• kuderera ndangariro
• dzungu
• kuneta
• musoro
• kurwadziwa kwemhasuru
• kuonda
• orthostatic hypotension (yakaderera BP inokonzera dzungu pakamira)

Truvada inogona kushandiswa kurapa herpes?

Dhipatimendi reU.S. reHutano neHuman Services harikurudziri Truvada yekudzivirira hutachiona hwehepe muvanhu vane hutachiona hweHIV.

Zvisinei, zvimwe zvidzidzo zvemakiriniki zvakayedza kana Truvada, kana ikashandiswa kuPrEP, inogona kudzivirira hutachiona hwehepe. Idzi dzidzo, dzinogona kuwanikwa pano neapo, dzaive nemisanganiswa yakasangana.

Kana iwe uine mibvunzo nezve kushandisa Truvada kurapa herpes, taura nachiremba wako kana wemishonga.

Ndinogona here kushandisa Tylenol pandinotora Truvada?

Iko hakuna kutaurirana kwakataurwa pakati peTylenol (acetaminophen) neTruvada. Nekudaro, kutora yakakwira madosi eTylenol kunogona kukonzera kukuvara kwechiropa. Mune zvimwe zviitiko, Truvada yakakonzerawo kukuvara kwechiropa. Kutora yakakwira madosi eTylenol pamwe neTruvada kunogona kuwedzera njodzi yako yekukuvara kwechiropa.

Kupera kweTruvada

Kana Truvada yapihwa kubva kupharmasi, wemishonga anozowedzera zuva rekupera kune zvakanyorwa pabhodhoro. Zuva iri rinowanzo kuve gore rimwe kubva musi wakapihwa mushonga. Chinangwa chezuva iri rekupera ndechekusimbisa kushanda kwemushonga panguva ino.

Chimiro chazvino cheKudya neDrug Administration (FDA) ndechekudzivirira kushandisa akapera mishonga. Zvisinei, chidzidzo cheDFA chakaratidza kuti mishonga yakawanda inogona kunge ichiri yakanaka kupfuura yekupera nguva yakanyorwa pane bhodhoro.

Inguva yakareba sei mushonga unoramba wakanaka unogona kubva pane zvakawanda zvinhu, zvinosanganisira kuti mushonga unochengeterwa kupi uye kupi. Truvada inofanirwa kuchengetwa mumudziyo wepakutanga pane tembiricha yemukati, panosvika 77 ° F (25 ° C).

Kana iwe usina kushandisa mishonga yakapfuura nguva yekupera, taura nachiremba wako nezvekuti ungangokwanisa kuishandisa.

Disiki: Nhau Dzokurapa Nhasi yakaedza zvese kuti ive nechokwadi chekuti ruzivo rwese nderwechokwadi, rwakakwana, uye rwechizvino-zvino. Nekudaro, chinyorwa ichi hachifanirwe kushandiswa sekutsiva ruzivo uye hunyanzvi hweane rezinesi rezvehutano. Iwe unofanirwa kugara uchibvunza chiremba wako kana imwe nyanzvi yehutano usati watora chero mushonga. Ruzivo rwezvinodhaka ruri pano runogona kuchinja uye haruna kuitirwa kufukidza ese mashandisirwo, madhairekitori, chenjedzo, kunyeverwa, kudyidzana kwezvinodhaka, allergic reaction, kana mhedzisiro. Kushaikwa kweyambiro kana rumwe ruzivo rwemushonga wakapihwa hakuratidze kuti mushonga kana musanganiswa wezvinodhaka wakachengeteka, unoshanda, kana wakakodzera kuvarwere vese kana kushandiswa kwese chaiko.