IgA nephropathy

IgA nephropathy chirwere cheitsvo umo masoja ekudzivirira anonzi IgA anovaka mutsvo dzeitsvo. Nephropathy kukuvara, chirwere, kana mamwe matambudziko neitsvo.

IgA nephropathy inonziwo chirwere cheBerger.

IgA ipuroteni, inonzi antibody, iyo inobatsira muviri kurwisa hutachiona. IgA nephropathy inoitika kana yakawandisa yeiri protein ichiiswa muitsvo. IgA inovaka mukati memidzi midiki yeropa yetsvo. Maumbirwo muitsvo anonzi glomeruli anopiswa uye kukuvara.

Dambudziko racho rinogona kuerekana raitika (zvakanyanya), kana kuwedzera kukura zvishoma pamakore mazhinji (chisingaperi glomerulonephritis).

Njodzi zvinhu zvinosanganisira:

• Nhoroondo yemunhu kana yemhuri yeIg nephropathy kana Henoch-Schönlein purpura, chimiro chevasculitis chinokanganisa zvikamu zvakawanda zvemuviri.
• Vachena kana veAsia dzinza

IgA nephropathy inogona kuitika muvanhu veese mazera, asi inowanzo bata varume mune vechidiki kusvika makore makumi matatu.

Panogona kunge pasina zviratidzo zvemakore mazhinji.

Kana paine zviratidzo, zvinogona kusanganisira:

• Weti weropa iyo inotanga panguva kana munguva pfupi mushure mekutapukira utachiona
• Dzokororo yezvikamu zverima kana reropa weti
• Kuzvimba kwemaoko nemakumbo
• Zviratidzo zvechirwere chetsvo chisingaperi

IgA nephropathy inowanzo kuwanikwa kana munhu asina zvimwe zviratidzo zvematambudziko eitsvo aine imwe kana zvimwe zvikamu zverima kana reropa weti.

Iko hakuna chaiko shanduko dzinoonekwa panguva yekuongorora kwepanyama. Dzimwe nguva, iyo BP inogona kunge yakakwira kana panogona kunge paine kuzvimba kwemuviri.

Miedzo inosanganisira:

• Ropa urea nitrogen (BUN) kuyera kuyera itsvo kushanda
• Creatinine ropa bvunzo kuyera itsvo basa
• Itsvo biopsy yekusimbisa kuongororwa
• Kuongorora urinal
• Weti immunoelectrophoresis

Chinangwa chekurapa ndechekudzora zviratidzo uye kudzivirira kana kunonoka kusingaperi kweitsvo kutadza.

Mushonga unogona kusanganisira:

• Angiotensin-inoshandura enzyme (ACE) inhibitors uye angiotensin receptor blockers (ARBs) kudzora kukwira kweropa uye kuzvimba (edema)
• Corticosteroids, mimwe mishonga inodzvinyirira immune system
• Mafuta ehove
• Mishonga yekudzikisa cholesterol

Munyu uye zvinwiwa zvinogona kudzorwa kudzora kuzvimba. Kudya kweprotein yakaderera-kusvika-pakati kunogona kukurudzirwa mune zvimwe zviitiko.

Pakupedzisira, vanhu vazhinji vanofanirwa kurapwa chirwere chisingaperi cheitsvo uye vangangoda dialysis.

IgA nephropathy inowedzera kukura zvishoma nezvishoma. Muzviitiko zvakawanda, hazvitonyanya kuwedzera zvachose. Mamiriro ako anogona kutonyanya kukura kana iwe uine:

• Kuwedzera kweropa
• Makuru mapuroteni mumurini
• Yakawedzera BUN kana creatinine mazinga

Fonera wako mupi wezvehutano kana uine weti ine ropa kana kana urikugadzira weti shoma pane yakajairwa.

Kufungidzira - IgA; Chirwere cheBerger

• Itsvo anatomi

Feehally J, Floege J. Immunoglobulin A nephropathy uye IgA vasculitis (Henoch-Schönlein purpura). Muna: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Yakakwana Kliniki Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019: chitsiko 23.

Saha MK, Pendergraft WF, Jennette JC, Falk RJ. Chirwere chepakutanga chinoratidzira. Mune: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner uye Rector Iyo Itsvo. 11th ed. Philadelphia, PA: Elsevier; 2020: chits. 31.