Sekondari systemic amyloidosis

Sekondari systemic amyloidosis chirwere umo mapuroteni asina kujairika anovaka mumatumbu uye nhengo. Clumps emapuroteni asina kujairika anonzi maamyloid deposits.

Sekondari zvinoreva kuti zvinoitika nekuda kwechimwe chirwere kana mamiriro. Semuenzaniso, chiitiko ichi chinowanzoitika nekuda kwenguva refu (chisingaperi) hutachiona kana kuzvimba. Mukupesana, chikuru amyloidosis zvinoreva kuti hapana chimwe chirwere chiri kukonzera mamiriro acho.

Systemic zvinoreva kuti chirwere chinokanganisa muviri wese.

Chikonzero chaicho chechipiri systemic amyloidosis hachizivikanwe. Iwe uri mukana wekuvandudza wechipiri systemic amyloidosis kana uine hutachiona hwenguva refu kana kuzvimba.

Aya mamiriro anogona kuitika ne:

• Ankylosing spondylitis - chimiro cheArthritis icho chinonyanya kubata mapfupa nemajoini musana
• Bronchiectasis - chirwere umo nzira huru dzemumapapu dzinokuvadzwa nehutachiona husingaperi
• Chisingaperi osteomyelitis - hutachiona hutachiona
• Cystic fibrosis - chirwere chinokonzera gobvu, inonamira mamasi kuvaka mumapapu, nzira yekugaya, uye dzimwe nzvimbo dzemuviri, zvichitungamira kuutachiona hutachiona hwemapapu.
• Kuzivikanwa kweMediterranean fever - nhaka yekugara nhaka yefivha inodzokororwa uye kuzvimba izvo zvinowanzo kukanganisa kumeso kwedumbu, chifuva, kana majoini
• Hairy cell leukemia - rudzi rwekenza yeropa
• Hodgkin chirwere - kenza yeiyo lymph tishu
• Juvenile idiopathic arthritis - arthritis inobata vana
• Multiple myeloma - rudzi rwekenza yeropa
• Reiter syndrome - boka remamiriro ezvinhu anokonzera kuzvimba uye kuzvimba kwemajoini, maziso, uye weti uye genital masisitimu)
• Rheumatoid arthritis
• Systemic lupus erythematosus - autoimmune kusagadzikana
• Tiibhii

Zviratidzo zvechipiri systemic amyloidosis zvinoenderana nemuviri wenyama unokanganiswa neprotein deposits. Izvi zvinokuvadza zvakajairika nyama. Izvi zvinogona kutungamira kune zviratidzo kana zviratidzo zvechirwere ichi, kusanganisira:

• Kubuda ropa muganda
• Kuneta
• Kusarongeka kwemoyo
• Chiveve chemaoko netsoka
• Mapundu
• Kufema kwekufema
• Kumedza matambudziko
• Dzimba dzakazvimba kana makumbo
• Rurimi rwakazvimba
• Ruoko rwakasimba
• Kuonda

Anopa hutano anozoongorora muviri uye obvunza nezve zviratidzo zvako.

Miedzo inogona kuitwa inosanganisira:

• Abdominal ultrasound (inogona kuratidza kuzvimba chiropa kana spleen)
• Biopsy kana kushuvira kwemafuta pazasi peganda (subcutaneous fat)
• Biopsy ye rectum
• Biopsy yeganda
• Biopsy yemapfupa emongo
• Ropa bvunzo, kusanganisira creatinine uye BUN
• Echocardiogram
• Electrocardiogram (ECG)
• Tsinga conduction velocity
• Kuongorora urinal

Mamiriro ari kukonzera amyloidosis anofanira kurapwa. Mune zvimwe zviitiko, chinodhaka colchicine kana biologic chinodhaka (mushonga unobata immune system) unorayirwa.

Kuita zvakanaka kwemunhu kunoenderana nenhengo dzinokanganiswa. Zvakare zvinoenderana nekuti chirwere chiri kukonzeresa chinogona kudzorwa here. Kana chirwere ichi chikabatanidza moyo neitsvo, zvinogona kutungamira kukundikana kwemuviri uye kufa.

Matambudziko ehutano anogona kukonzerwa neyechipiri systemic amyloidosis anosanganisira:

• Endocrine kutadza
• Kutadza kwemoyo
• Itsvo kutadza
• Kukundikana kwekufema

Fonera mupiki wako kana iwe uine zviratidzo zveichi chiitiko. Izvi zvinotevera zviratidzo zvakakomba zvinoda kurapwa nekukurumidza:

• Kubuda ropa
• Kusarongeka kwemoyo
• Unhu
• Kufema kwekufema
• Kuzvimba
• Kubata zvisina simba

Kana iwe uine chirwere chinozivikanwa kuwedzera njodzi yako pachiitiko ichi, ita shuwa kuti unorapwa. Izvi zvinogona kubatsira kudzivirira amyloidosis.

Amyloidosis - yechipiri systemic; AA amyloidosis

• Amyloidosis yeminwe
• Amyloidosis yechiso
• Antibodies

Gertz MA. Amyloidosis. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 188.

Papa R, Lachmann HJ. Sekondari, AA, Amyloidosis. Rheum Dis Clin North Am. 2018; 44 (4): 585-603. PMID: 30274625 www.ncbi.nlm.nih.gov/pubmed/30274625.