Urticaria pigmentosa

Urticaria pigmentosa chirwere cheganda chinoburitsa zvigamba zveganda rakasviba uye kuruma kwakanyanya. Mikoko inogona kukura kana nzvimbo idzi dzeganda dzakwizwa.

Urticaria pigmentosa inoitika kana paine akawandisa maseru ekuzvimba (mast cell) muganda. Mast maseru maseru emuviri anobatsira muviri kurwisa hutachiona. Mast maseru anogadzira uye aburitse histamine, iyo inokonzeresa matishu ari padhuze kuzvimba uye kuzvimba.

Zvinhu zvinogona kukonzera histamine kuburitswa uye zviratidzo zveganda zvinosanganisira:

• Kusvina ganda
• Zvirwere
• Rovedza muviri
• Kunwa zvinwiwa zvinopisa, kudya chikafu chinonaka
• Chiedza chezuva, kusvikirwa nechando
• Mishonga, yakadai seaspirin kana mamwe maNSAID, codeine, morphine, x-ray dhayi, mimwe mishonga yeanesthesia, doro

Urticaria pigmentosa inonyanya kuwanikwa muvana. Inogonawo kuitika kune vanhu vakuru.

Chiratidzo chikuru mabara akasviba paganda. Aya mavara ane masero anonzi mastocyte. Kana mastocyte aburitsa kemikari histamine, iwo matinji anokura kuita mikoko-kunge mapundu. Vana vadiki vanogona kukura blister iyo izere nefluidhi kana bundu rakakweshwa.

Chiso chinogona zvakare kutsvuka nekukasira.

Muzviitiko zvakakomba, izvi zviratidzo zvinogona kuitika:

• Manyoka
• Kufenda (zvisingawanzoitika)
• Kutemwa nemusoro
• Wheeze
• Kukurumidza kurova kwemoyo

Anopa hutano anoongorora ganda. Iye mupi anogona kufungidzira urticarial pigmentosa kana zviganda zveganda zvakwizwa nekusimudza mapundu (mikoko) inokura. Ichi chinonzi chiratidzo cheDarier.

Miedzo yekutarisa mamiriro aya ndeiyi:

• Ganda biopsy kutsvaga yakawanda nhamba yemasero maseru
• Weti histamine
• Kuongororwa kweropa kwemasero eropa uye huwandu hweropa tryptase (tryptase is enzyme inowanika mumasero maseru)

Antihistamine mishonga inogona kubatsira kubvisa zviratidzo sekurumwa uye kupururudza. Taura nemupi wako nezvekuti ndeupi rudzi rweantihistamine yekushandisa. Corticosteroids inoshandiswa paganda uye kurapwa kwakapfava kunogona zvakare kushandiswa mune dzimwe nguva.

Wako mupi anogona kupa mamwe marudzi emishonga yekurapa zviratidzo zvemhando dzakakomba uye dzisina kujairika dzeurticaria pigmentosa.

Urticaria pigmentosa inoenda nekuyaruka mune ingangoita hafu yevana vakanganiswa. Zviratidzo zvinowanzo kuve nani mune vamwe sezvavanokura kuva vanhu vakuru.

Muvanhu vakuru, urticaria pigmentosa inogona kutungamira kune systemic mastocytosis. Ichi chiitiko chakakomba chinogona kukanganisa mapfupa, huropi, tsinga, uye gadziriro yekugaya.

Idzo huru matambudziko kusagadzikana kubva kuvava uye kunetseka nezvechitarisiko chemavara. Mamwe matambudziko akaita semanyoka uye kupera simba kashoma.

Zvipembenene zvinokonzeresa zvinogona kukonzeresa kutadza kugarisana nevanhu vane urticaria pigmentosa. Kumbira mupiki wako kana iwe uchifanira kutakura epinephrine kit yekushandisa kana iwe ukawana nyuchi.

Fonera waunopa kana iwe ukaona zviratidzo zveurticaria pigmentosa.

Mastocytosis; Mastocytoma

• Urticaria pigmentosa muhapwa
• Mastocytosis - inopararira yakatemwa
• Urticaria pigmentosa pachifuva
• Urticaria pigmentosa - pedyo-kumusoro

Chapman MS. Urticaria. Mune: Habif TP, Dinulos JGH, Chapman MS, Zug KA, eds. Zvirwere zveganda: Kuongorora uye Kurapa. 4th ed. Philadelphia, PA: Elsevier; 2018: chits. 3.

Chen D, George TI. Mastocytosis. Mune: Hsi ED, ed. Hematopathology. 3rd ed. Philadelphia, PA: Elsevier; 2018: chitsiko 20.

Paige DG, Wakelin SH. Chirwere cheganda. Mune: Kumar P, Clark M, eds. Kumar uye Clarke's Clinical Medicine. 9th ed. Philadelphia, PA: Elsevier; 2017: chits. 31.