CPK isoenzymes bvunzo

Iyo creatine phosphokinase (CPK) isoenzymes bvunzo inoyera akasiyana mafomu eCPK muropa. CPK i enzyme inowanikwa kunyanya mumoyo, huropi, uye mhasuru yemhasuru.

Muenzaniso weropa unodiwa. Izvi zvinogona kutorwa kubva mutsinga. Muedzo unonzi venipuncture.

Kana iwe uri muchipatara, bvunzo iyi inogona kudzokororwa kupfuura maviri kana matatu mazuva. Kumuka kwakakura kana kudonha muiyo yakazara CPK kana CPK isoenzymes inogona kubatsira wako mupi wekuchengetedza hutano kuti aongorore mamwe mamiriro.

Hapana gadziriro yakakosha inodiwa muzviitiko zvakawanda.

Udza mupiki wako nezveese mishonga yauri kutora. Mimwe mishonga inogona kukanganisa mhedzisiro yekuedzwa. Zvinodhaka zvinogona kuwedzera zviyero zveCPK zvinosanganisira zvinotevera:

• Doro
• Amphotericin B
• Mamwe maanesthetics
• Cocaine
• Fibrate zvinodhaka
• Statins
• Steroid, senge dexamethasone

Rondedzero iyi haisi yese-inosanganisira.

Unogona kunzwa kurwadziwa kushoma kana tsono ikaiswa kuti utore ropa. Vamwe vanhu vanongonzwa kubaya kana kurira. Mushure meizvozvo, panogona kunge paine kurovera.

Bvunzo iyi inoitwa kana bvunzo yeCPK inoratidza kuti yako yakazara CPK nhanho yakakwira. CPK isoenzyme kuyedza kunogona kubatsira kuwana chaiko sosi yenyama yakakanganiswa.

CPK inogadzirwa nezvinhu zvitatu zvakasiyana zvakasiyana:

• CPK-1 (inonziwo CPK-BB) inowanikwa zvakanyanya muuropi nemapapu
• CPK-2 (inonziwo CPK-MB) inowanikwa zvakanyanya mumoyo
• CPK-3 (inonziwo CPK-MM) inowanikwa kunyanya mumhasuru yemhasuru

Yakakwirira-kupfuura-yakajairwa CPK-1 mazinga:

Nekuti CPK-1 inowanikwa zvakanyanya muuropi nemapapu, kukuvara kune imwe yenzvimbo idzi kunogona kuwedzera mazinga eCPK-1. Yakawedzera CPK-1 mazinga anogona kunge achikonzerwa ne:

• Kenza yehuropi
• Kukuvara kwehuropi (nekuda kwemhando ipi neipi yekukuvara inosanganisira, kurohwa, kana kubuda ropa muuropi)
• Electroconvulsive kurapa
• Pulmonary infarction
• Kufenda

Yakakwirira-kupfuura-yakajairwa CPK-2 mazinga:

CPK-2 nhanho dzinokwira 3 kusvika maawa matanhatu mushure mekurwadziwa kwemoyo. Kana pasina kumwe kukuvara kwemhasuru yemoyo, iyo nhanho inokwira pamaawa gumi nemaviri kusvika makumi maviri nemana uye inodzokera kune yakajairika maawa gumi nemaviri kusvika makumi mana nemasere mushure mekufa kwemaviri.

Yakawedzera CPK-2 mazinga anogona zvakare kuve nekuda kwe:

• Kukuvara kwemagetsi
• Moyo defibrillation (zvine chinangwa kuvhundutsa kwemoyo nevashandi vekurapa)
• Kukuvara kwemoyo (semuenzaniso, kubva mutsaona yemotokari)
• Kuzvimba kweiyo moyo mhasuru kazhinji nekuda kwehutachiona (myocarditis)
• Vhura kuvhiyiwa kwemoyo

Yakakwira-kupfuura-yakajairwa CPK-3 mazinga anowanzo kuve chiratidzo chekukuvara kwemhasuru kana kushushikana kwemhasuru. Zvinogona kunge zvichikonzerwa ne:

• Kupwanya kukuvara
• Kukanganiswa kwemhasuru nekuda kwemishonga kana kusafamba kwenguva yakareba (rhabdomyolysis)
• Tsandanyama dystrophy
• Myositis (skeletal mhasuru kuzvimba)
• Kugamuchira majekiseni mazhinji epamo
• Munguva pfupi yapfuura nerve uye mhasuru basa rekuyedza (electromyography)
• Nguva pfupi yapfuura kubata
• Kuvhiya kwazvino
• Kurovedza muviri kunonetsa

Zviitiko zvinogona kukanganisa mhedzisiro bvunzo zvinosanganisira moyo catheterization, majekiseni epamuviri, kuvhiya kuchangobva kuitika, uye nesimba uye kwenguva refu kurovedza muviri kana kudzikamisa.

Isoenzyme kuyedza chaiyo mamiriro ndeye 90% chaiyo.

Gadzira phosphokinase - isoenzymes; Zvisikwa kinase - isoenzymes; CK - isoenzymes; Kurwadziwa kwemoyo - CPK; Kupwanya - CPK

• Kuongorora ropa

Anderson JL. St chidimbu kukwirira kwakapinza myocardial infarction uye kunetsekana kweye myocardial infarction. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits 73.

Marshall WJ, Zuva A, Lapsley M. Plasma mapuroteni nema enzymes. Muna: Marshall WJ, Zuva A, Lapsley M, eds. Clinical Chemistry. 8th ed. Philadelphia, PA: Elsevier; 2017: chits.

Nagaraju K, Gladue HS, Lundberg IE. Zvirwere zvinopisa zvemhasuru uye mamwe maopathies. Mune: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley uye Firestein's Bhuku reRheumatology. 10th ed. Philadelphia, PA: Elsevier Saunders; 2017: chits. 85.

Selcen D. Zvirwere zvetsandanyama. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chitsuwa 421.