Mipomersen jekiseni

Zvemukati

• Usati wabaya jekiseni remipomersen,
• Mipomersen jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Mipomersen jekiseni inogona kukonzera kukuvara kwechiropa. Udza chiremba wako kana iwe uchinwa kana wakambonwa doro rakawanda uye kana iwe kana wakambove nechirwere chechiropa, kusanganisira kukuvara kwechiropa kwakaitika iwe pawaitora mumwe mushonga. Chiremba wako angangokuudza kuti usashandise jekiseni yemipomersen kana uine chirwere chechiropa. Udza chiremba wako uye wemishonga kana uchigara uchitora acetaminophen (Tylenol, mune mimwe mishonga yekurwadziwa) uye kana uri kutora amiodarone (Cordarone, Pacerone); mimwe mishonga yecholesterol yakakwira; methotrexate (Rheumatrex, Trexall); tamoxifen (Soltamox); kana tetracycline mishonga yekurwisa mabhakitiriya yakaita se doxycycline (Doryx, Vibra-Tabs, Vibramycin), minocycline (Dynacin, Minocin), uye tetracycline (Sumycin). Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, dana chiremba wako nekukurumidza: kusvotwa, kurutsa, kurasikirwa nechido, kurwadziwa mudumbu, kuneta zvakanyanya, yero yeganda kana maziso, weti yakasviba, kana kuchenesa.

Kunwa doro kunowedzera njodzi yekuti unozokuvara chiropa panguva yekurapa kwako neipomersers jekiseni. Usanwa zvinopfuura chimwe chete chinwiwa pazuva paunenge uchishandisa mushonga uyu.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako achaodha zvimwe bvunzo usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune mipomersen jekiseni.

Nekuda kwenjodzi yekukuvara kwechiropa, chirongwa chakamisikidzwa kuongorora varwere vachishandisa jekiseni remipomersen. Chiremba wako anozoda kupedzisa kudzidziswa uye kunyoresa nechirongwa usati wanyora uyu mushonga. Iwe unozongokwanisa chete kugamuchira mishonga yako kubva kufamasi yakave yakazivikanwa kuti igone mipomersen jekiseni. Kumbira chiremba wako kuti uwane rumwe ruzivo nezvekuti ungawana sei mushonga wako.

Chiremba wako kana wemishonga achakupa gwaro reruzivo rwevarwere (reMedicine Gwara) paunotanga kurapwa nejekiseni remipomersen uye nguva yega yega paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekushandisa jekiseni remipomersen.

Jekiseni reMipomersen rinoshandiswa kudzikisa huwandu hwecholesterol uye zvimwe zvinhu zvine mafuta muropa muvanhu vane homozygous mhuri yemhuri hypercholesterolemia (HoFH; yakasarudzika nhaka mamiriro ayo anokonzeresa zvakanyanya cholesterol mumuropa, ichiwedzera njodzi yechirwere chemwoyo chakakomba). Vamwe vanhu vane HoFH vanogona kurapwa neLDL apheresis (maitiro anobvisa LDL muropa), asi jekiseni remipomersen harifanirwe kushandiswa pamwe nemushonga uyu. Mipomersen jekiseni haifanire kushandiswa kudzikisa cholesterol mwero muvanhu vasina HoFH. Mipomersen jekiseni iri mukirasi yemishonga inonzi antisense oligonucleotide (ASO) inhibitors. Inoshanda nekudzivirira mamwe mafuta zvinhu kubva pakuumba mumuviri.

Mipomersen jekiseni inouya semhinduro yekubaya pasi peganda. Inowanzojowa kamwe chete pasvondo. Jekiseni jekiseni remipomersen pazuva rimwe chete revhiki uye panguva dzakatenderedza nguva imwe neimwe nguva yaunoibaya. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Shandisa jekiseni remipomersen chaizvo sezvakarairwa. Usaise jekiseni zvakanyanya kana zvishoma kana kuijowa kakawanda kupfuura zvakatemwa nachiremba wako.

Mipomersen jekiseni inogona kubatsira kudzora cholesterol yako asi haizorape mamiriro ako. Zvinogona kutora mwedzi mitanhatu kana kupfuura kuti cholesterol yako idzikire zvakanyanya. Enderera kushandisa mipomersen jekiseni kunyangwe uchinzwa mushe. Usarega kushandisa jekiseni remupomersen usina kutaura nachiremba wako.

Unogona kuzvibaya mipomersen pachako kana kuva neshamwari kana hama inopinza mushonga kwauri. Chiremba wako achakuratidza kana iye munhu achange achibaisa mushonga mushonga wekubaya jekiseni. Iwe nemunhu achange achibaya mushonga unofanira kuverenga mirairo yekugadzira yekushandisa inouya nemushonga. Bvunza chiremba wako kana iwe uine chero mubvunzo kana usinganzwisise maitiro ekubairira mipomersen.

Mipomersen jekiseni inouya pre-yakazadza majekiseni uye mumidziyo. Kana iwe uri kushandisa hombodo dzeipomersen jekiseni, chiremba wako anokuudza iwe rudzii rwejekiseni raunofanira kushandisa uye maitiro aunofanira kukwevera mushonga mujekiseni. Usasanganise chero mimwe mishonga musirinji nejekiseni yemipomersen.

Tora jekiseni remipomersen kunze kwefriji maminetsi makumi matatu usati waronga kuribaya kuti ubvumire mushonga kuti uuye kutembiricha yemukamuri. Chengeta sirinji mumapakeji ayo kuti uichengetedze kubva pachiedza panguva ino. Usaedze kudziyisa sirinji nekuipisa iyo neimwe nzira.

Gara uchitarisa jekiseni remupomersen usati wabaya jekiseni. Ive neshuwa kuti kurongedza kwakavharwa, kusakanganiswa uye kwakanyorwa zita chairo remushonga uye zuva rekupera risingapfuure. Tarisa uone kuti mhinduro mune vial kana jekiseni iri yakajeka uye isina ruvara kana zvishoma yero. Usashandise bhodhoro kana sirinji kana rakakuvara, rapera basa, rakatsvukiswa, kana rine makore kana riine zvidimbu.

Unogona kubaya mipomersen chero kupi kune chikamu chekunze kwemaoko ako ekumusoro, zvidya zvako, kana dumbu rako, kunze kweguvhu rako (dumbu bhatani) nenharaunda 2 inches kutenderedza. Sarudza imwe nzvimbo nguva imwe neimwe paunobaya mushonga. Usabaya jira paganda rakatsvuka, rakazvimba, rine hutachiona, rinemavanga, rakatemwa nyora, rakatsva nezuva kana rinobatwa nekuputika kana chirwere cheganda senge psoriasis.

Yese sirinji-pre-yakazadzwa kana vial inongova neinokwana mipomersen jekiseni rimwe chete. Usaedze kushandisa magaba kana majekiseni kanopfuura kamwe. Rasa majekiseni akamboshandiswa mumudziyo unodzivira. Kumbira chiremba wako kana wemishonga kuti ungarasa sei mudziyo usingadzivirirwe.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wabaya jekiseni remipomersen,

• udza chiremba wako uye wemishonga kana uri weergoria kune mipomersen, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujekiseni yemipomersen. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa mune CHINOKOSHA CHENYENZO chikamu. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• usabaye chero mimwe mishonga panguva imwechete yaunobaya mipomersen. Kumbira chiremba wako kana wemishonga nguva yekubaya mishonga yako.
• udza chiremba wako kana iwe kana wakambove nechirwere cheitsvo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri panguva yekurapwa kwako, rega kushandisa mipomersen jekiseni uye udane chiremba wako nekukurumidza.

Idya yakaderera-mafuta, yakaderera-cholesterol chikafu. Ive neshuwa yekutevera zvese zvekurovedza muviri uye zvekudya zvinokurudzirwa zvakaitwa nachiremba wako kana wezvekudya. Iwe unogona zvakare kushanyira iyo National Cholesterol Dzidzo Chirongwa (NCEP) webhusaiti pa http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf kune rumwe ruzivo rwekudya.

Kana iwe uchirangarira kanokwana mazuva matatu pamberi peyako yakatarwa inotevera dosi, tora iyo yakarasika dosi ipapo ipapo. Nekudaro, kana iwe uchirangarira isingasviki mazuva matatu pamberi peyako yakatarwa inotevera dosi, ruka iro rakarasika dosi uye pfuurira yako yenguva dzose dosing purogiramu. Usapinda jekiseni repaviri kuti uwane iyo yakarasika.

Mipomersen jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kutsvuka, kurwadziwa, unyoro, kuzvimba, kutsvuka, kuchenesa, kana kupwanya kweganda kwawakabaya mipomersen
• dzihwa-senge zviratidzo zvakaita sefivha, kutonhora, kurwadziwa kwemhasuru, kurwadza kwemajoini, kushaya simba, uye kuneta izvo zvinowanzoitika mukati memazuva maviri ekutanga mushure mekubaya mipomersen
• musoro
• kunetseka kurara kana kuramba wakarara
• kurwadziwa mumaoko kana makumbo

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kurwadziwa pachipfuva
• kurova kwehana
• kuzvimba kwemaoko, maoko, tsoka, makumbo, kana makumbo ezasi
• mapundu
• mikoko
• kuzvimba kwechiso, huro, rurimi, miromo, kana maziso
• hoarseness
• kunetseka kumedza kana kufema

Mipomersen jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchishandisa mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Chengetedze mufiriji uye chengetedza kubva pachiedza. Kana pasina firiji iripo, unogona kuchengeta mishonga mukamuri yekupisa kwemazuva gumi nemana.

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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