Munyori: Gregory Harris
Zuva Rekusika: 15 Kubvumbi 2021
Gadziridza Zuva: 19 Mbudzi 2024
Anonim
Tafenoquine: Malaria Drug Development
Vhidhiyo: Tafenoquine: Malaria Drug Development

Zvemukati

Tafenoquine (Krintafel) inoshandiswa kudzivirira kudzoka kwemarariya (hutachiona hwakakomba hunoparadzirwa nehumhutu mune mamwe mativi epasi uye hunogona kukonzera rufu) muvanhu vane makore gumi nematanhatu zvichikwira vane hutachiona uye vari kutambira chloroquine kana hydroxychloroquine kurapa malaria. Tafenoquine (Arakoda) inoshandiswa yoga kudzivirira malaria kune vafambi vanoshanyira nzvimbo dzinowanikwa malaria. Tafenoquine iri mukirasi yemishonga inonzi antimalarials. Inoshanda nekuuraya zvipuka zvinokonzera malaria.

Tafenoquine inouya semapiritsi ekutora nemuromo nechikafu. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora tafenoquine chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe uri kutora tafenoquine (Krintafel) kudzivirira malaria kubva mukudzoka, inowanzo kutorwa seyadhi imwe chete (mapiritsi maviri) pazuva rekutanga kana rechipiri rerapa rako nechloroquine kana hydroxychloroquine.


Kana iwe uri kutora tafenoquine (Arakoda) yekudzivirira malaria, imwe dose (mapiritsi maviri) inowanzo kutorwa kamwe chete pazuva kwemazuva matatu, kutanga mazuva matatu usati waenda kunzvimbo ine malaria. Paunenge uri munzvimbo iyi, imwe dhi (mapiritsi maviri) anowanzo kutorwa kamwe pasvondo pazuva rimwe chete revhiki. Mushure mekudzoka kubva kunharaunda, imwe dhi (mapiritsi maviri) inowanzo kutorwa mazuva manomwe mushure meiyo yekupedzisira dhizaini yakatorwa usati wadzoka. Haufanire kutora tafenoquine (Arakoda) yekudzivirira malaria kweinopfuura mwedzi mitanhatu.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Kana iwe ukarutsa mukati meawa mushure mekutora tafenoquine (Krintafel), fonera chiremba wako. Ungangoda kutora imwe dosi yemushonga uyu.

Tora tafenoquine kusvikira wapedza kunyorera, kunyangwe kana uchinzwa zvirinani. Kana iwe ukarega kutora tafenoquine nekukurumidza kana kusvetuka madosi, hutachiona hwako hunogona kusarapwa zvakakwana kana kuti ungangodzivirirwa kubva kuzvirwere zvenguva yemberi.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere kana uri kutora Tafenoquine (Krintafel). Kana iwe uri kutora tafenoquine (Arakoda), chiremba wako kana wemishonga anokupa iwe mugadziri wemurwere gwaro rezita (Medication Gwara) paunotanga kurapwa uye nguva imwe neimwe paunozadza tsamba yako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti utore Gwaro reMishonga.


Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora tafenoquine,

  • udza chiremba wako uye wemishonga kana uri weergoria kune tafenoquine, primaquine, chero mimwe mishonga, kana chero chipi chinosanganiswa mumapiritsi etafenoquine.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: dofetilide (Tikosyn) uye metformin (Fortamet, Glucophage, Riomet, muActoplus Met, vamwe). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana uine glucose-6-phosphate dehydrogenase (G-6-PD) kushomeka (chirwere cheropa chakagarwa nhaka). Chiremba wako angangokuudza kuti usatore tafenoquine. Uyezve udza chiremba wako kana iwe kana wakambove nematambudziko ehutano hwepfungwa. Chiremba wako anogona kukuudza kuti usatore tafenoquine.
  • udza chiremba wako kana iwe wakambove kana hemolytic anemia (mamiriro ane huwandu husina kujairika hwemasero matsvuku eropa), methemoglobinemia (mamiriro ane masero matsvuku eropa asingakwanise kutakura okisijeni kumatumbu mumuviri), nicotinamide adenine dinucleotide (NADH) kushomeka (chibereko), kana itsvo kana chirwere chechiropa.
  • udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Kana iwe uri mukadzi ane zera rekubereka, uchafanirwa kutora bvunzo yepamuviri usati watanga kurapwa. Iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako ne tafenoquine uye kwemwedzi mitatu mushure mekupedzisira kwako. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora tafenoquine, dana chiremba wako nekukurumidza. Tafenoquine inogona kukuvadza fetus.
  • udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.


Fonera chiremba wako kana wemishonga kuti ubvunze zvekuita kana ukarasikirwa neiyo tafenoquine (Arakoda).

Tafenoquine inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kusvotwa
  • kurutsa
  • manyoka
  • kunetseka kurara kana kuramba wakarara
  • kushushikana
  • kuchinja manzwiro
  • kujairika kurota
  • musoro
  • matambudziko ekuona, kusanganisira kusaona zvakanaka kana kunzwisisika pachiedza

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • mapundu
  • mikoko
  • kuzvimba kwemaziso, kumeso, miromo, rurimi, muromo, kana huro
  • kunetseka kufema kana kumedza
  • mweya wekufema
  • kuvhunduka kana kuoma pahuro
  • weti yakasviba
  • pfumbu-bhuruu ruvara rwemiromo uye / kana ganda
  • dzungu
  • kuvhiringidzika
  • kufungidzira (kuona zvinhu kana kunzwa manzwi zvisipo)
  • kunyengera (kuva nepfungwa dzisinganzwisisike kana zvitendero zvisina hwaro muzvokwadi) senge mifungo iyo vanhu vari kuyedza kukukuvadza kunyangwe isiri iyo
  • musoro wakareruka
  • yero yeganda kana maziso

Tafenoquine inogona kukonzera mamwe mhedzisiro.Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune tafenoquine.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Arakoda®
  • Krintafel®
Yekupedzisira Yakagadziridzwa - 02/15/2021

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