Elexacaftor, Tezacaftor, uye Ivacaftor

Zvemukati

• Usati watora musanganiswa weelexacaftor, tezacaftor, uye ivacaftor,
• Iko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor kunogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Iko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor kunoshandiswa kurapa mamwe marudzi ecystic fibrosis (chirwere chinoberekwa chinokonzera matambudziko nekufema, kugaya, uye kubereka) muvanhu vakuru uye vana vane makore gumi nemaviri ekuberekwa nekure. Iyo inofanirwa kushandiswa chete muvanhu vane imwe genetiki yekugadzira. Chiremba wako anogona kuraira kuongororwa kweropa kuti ubatsire kusarudza kana mushonga uyu wakanakira iwe. Elexacaftor uye tezacaftor vari mukirasi yemishonga inonzi cystic fibrosis transmembrane conductance regulator (CFTR) inogadzirisa. Ivacaftor iri mukirasi yemishonga inonzi cystic fibrosis transmembrane conductance regulator (CFTR) potentiators. Iyi mishonga inoshanda nekuvandudza mashandiro eprotein mumuviri kudzikisira kuvaka-kwemukati mamota mumapapu nekuvandudza zvimwe cystic fibrosis zviratidzo.

Iko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor kunouya sematafura ekutora nemuromo. Dhivha yega yega yezuva nezuva ine mhando dzakasiyana dzemapiritsi: piritsi rimwe chete ndiko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor uye imwe piritsi ivacaftor. Tora elexacaftor, tezacaftor, uye ivacaftor (mahwendefa maviri eorenji) mangwanani ega ega nechikafu chine mafuta uye ivacaftor (1 piritsi rebhuruu) manheru ega ega nechikafu chine mafuta, akaparadzanisa maawa gumi nemaviri. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora mishonga iyi chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Tora mubatanidzwa weelexacaftor, tezacaftor, uye ivacaftor ine mafuta ane chikafu senge mazai, bota, nzungu, nzungu ruomba, chizi pizza, uye yakazara-mukaka zvigadzirwa zvemukaka (semukaka wese, chizi, uye yogati) Taura nachiremba wako nezve zvimwe zvekudya zvine mafuta zvekudya nemishonga iyi.

Iko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor inoshanda kudzora cystic fibrosis, asi hairape.Ramba uchitora mishonga iyi kunyangwe uchinzwa zvakanaka. Usarega kutora mishonga iyi usingatauri nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora musanganiswa weelexacaftor, tezacaftor, uye ivacaftor,

• udza chiremba wako uye wemishonga kana uri weergoria kune elexacaftor, tezacaftor, uye ivacaftor chero mimwe mishonga, kana chero chinhu chinosanganiswa mu elexacaftor, tezacaftor, uye mahwendefa eivacaftor. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera zvinovaka muviri, zvauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe maantibhakitiriya akadai clarithromycin (Biaxin, muPrevPac) uye erythromycin (EES, E-Mycin, Ery-Tab, Erythrocin); mamwe maantifungal akadai fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, posaconazole (Noxafil), uye voriconazole (Vfend); cholesterol-kudzikisa mishonga (statins) senge atorvastatin (Lipitor, muCaduet), fluvastatin (Lescol), lovastatin (Altoprev), pravastatin (Pravachol), rosuvastatin (Crestor), uye simvastatin (Zocor, muVytorin); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); everolimus (Afinitor, Zortress); glimepiride (Amaryl); glipizide (Glucotrol); glyburide (Diabeta); mishonga yekudzivirira mhuri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, mapiritsi, kana majekiseni); mimwe mishonga yekubatwa kwakadai se carbamazepine (Carbatrol, Epitol, Tegretol, vamwe), phenobarbital, uye phenytoin (Dilantin, Phenytek); nateglinide; repaglinide; rifabutin (Mycobutin); rifampin (Rifadin, muRifamate, muRifater, Rimactane); sirolimus (Rapamune); tacrolimus (Astagraf, Prograf), kana warfarin (Coumadin, Jantoven). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana ne elexacaftor, tezacaftor, kana ivacaftor, saka ive shuwa yekuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort. Chiremba wako angangokuudza kuti usatora St. John's wort uchitora mubatanidzwa weelexacaftor, tezacaftor, uye ivacaftor.
• udza chiremba wako kana iwe wakambove kana wakambove nechiropa kana itsvo chirwere.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora musanganiswa weelexacaftor, tezacaftor, uye ivacaftor, fonera chiremba wako.
• iwe unofanirwa kuziva kuti iyi mishonga inogona kukuita iwe uchikotsira. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti mishonga iyi inokukanganisa sei.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mishonga iyi.

Kana iwe uchirangarira mangwanani kana manheru akarasikirwa nedosi mukati maawa matanhatu yenguva yawakange wakarongerwa kuitora, tora dhosi rakarasika ipapo nechikafu chine mafuta uye ramba uchiita yako yenguva dzose dosing purogiramu. Nekudaro, kana anopfuura maawa matanhatu apfuura kubva panguva yakatarwa yekutora yako mangwanani dhosi, tora chakarasika mangwanani dhiza nekukurumidza uye svetuka yemanheru muyero, wobva waenderera neyako yakajairwa dosing purogiramu. Kana anopfuura maawa matanhatu apfuura kubva panguva yakatarwa yekutora muyero wemanheru, ruka iro rakarasika remanheru uye ramba uchiita yako yenguva dzose dosing purogiramu. Usatore madosi emangwanani nemanheru pamwe chete kuti uwane imwe yakashaikwa.

Iko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor kunogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• inoyerera mhino, kuhotsira, uye kumonera; kupindwa nechando; kukosora; kana zvimwe zviratidzo zvehutachiona
• kurwadziwa nemudumbu kana kuzvimba
• manyoka
• mapundu
• gasi
• ziso repingi
• kuvava

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• yero yeganda kana maziso
• kurasikirwa nenzara
• kusvotwa
• kurutsa
• zvituru zvakachenuruka
• kurwadziwa nemudumbu
• weti yakasviba

Iko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor kunogona kukonzera cataract (kufukidza lens yemeso iyo inogona kukonzera matambudziko ekuona) muvana nevechiri kuyaruka. Vana nevachiri kuyaruka vanotora elexacaftor, tezacaftor, uye ivacaftor vanofanirwa kuona chiremba wemaziso vasati uye panguva yekurapwa kwavo. Taura nachiremba wemwana wako nezve njodzi dzekupa elexacaftor, tezacaftor, uye ivacaftor kumwana wako.

Iko kusanganiswa kweelexacaftor, tezacaftor, uye ivacaftor kunogona kukonzera mimwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira kuongorora kwemaziso (kwevana nevechiri kuyaruka) uye kumwe kuongorora kwelebhu kwakadai sekuyedzwa kwechiropa usati uye panguva yekurapwa kwako kuti utarise mhinduro yemuviri wako kune elexacaftor, tezacaftor, uye ivacaftor.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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