Selpercatinib

Zvemukati

• Usati watora selpercatinib,
• Selpercatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Selpercatinib inoshandiswa kurapa imwe mhando yekenza isiri-diki yemapapu kenza (NSCLC) muvakuru yakapararira kune zvimwe zvikamu zvemuviri kuvanhu vakuru. Iyo inoshandiswa zvakare kurapa imwe mhando yekenza yehutachiona muvakuru uye vana vane makore gumi nemaviri ekuberekwa uye yakapararira kune dzimwe nhengo dzomuviri. Selpercatinib inoshandiswawo kurapa rumwe rudzi rwegomarara remukaka wakapararira kune dzimwe nhengo dzemuviri muvanhu vakuru nevana vane makore gumi nemaviri zvichikwira izvo zvakarapwa zvisina kubudirira iodine ine radioactive. Selpercatinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.

Selpercatinib inouya sekapuleti kutora nemuromo. Inowanzo kutorwa kaviri pazuva (maawa gumi nemaviri) uine kana pasina chikafu. Tora selpercatinib panguva dzakatenderedza nguva dzakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora selpercatinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsules akazara; usavhure, kutsenga, kana kuapwanya.

Kana iwe ukarutsa mushure mekutora selpercatinib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kudzikisira muyero wako, kana kukanganisa kana kurega kurapwa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye nemhedzisiro iwe yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora selpercatinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora selpercatinib usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora selpercatinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoriki kune selpercatinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumaselpercatinib capsules. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: antifungals senge fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, uye voriconazole (Vfend); aprepitant (Simbisa); carbamazepine (Carbatrol, Tegretol, Equetro, nevamwe); clarithromycin (Biaxin, muPrevpac); diltiazem (Cardizem, Cartia, Tiazac, nevamwe); erythromycin (EES, E-Mycin, Erythrocin); mimwe mishonga yehutachiona hwehutachiona hweHIV (HIV) kana kuwana immunodeficiency syndrome (AIDS) inosanganisira efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, muKaletra), uye saquinavir (Invirase) ; nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos); quinidine (muNuedexta); repaglinide (Prandin); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, muRifamate, muRifater); uye verapamil (Calan, Verelan, vamwe). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana ne selpercatinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• kana uri kutora H₂ blocker mishonga yekugaya, kuora moyo, kana ulcers senge cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), kana ranitidine (Zantac), tora selpercatinib kweinenge maawa maviri pamberi kana maawa gumi mushure mekutora mumwe wemishonga iyi.
• kana uri kutora antacid ine aruminiyamu, magnesium, calcium, kana simethicone; kana mabuffered mishonga yakadai seyakasungwa aspirin, tora selpercatinib kanenge maawa maviri zvisati zvaitika kana angangoita maawa maviri mushure mekutora imwe yemishonga iyi.
• kana iwe uri kutora proton-pombi inhibitor senge esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), uye rabeprazole (AcipHex), tora dhosi rega rega re selpercatinib pamwe nechikafu.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe wakambove nekumwe kunonoka, nekukurumidza, kana kusagadzikana kwemwoyo; nguva yakareba yeQT (chinetso chemoyo chisingawanzo chinogona kukonzera kurova kwemoyo zvisina kujairika, kufenda, kana kufa kamwe kamwe); kukwirira kweropa; matambudziko ekubuda ropa; kana hosha yeitsvo kana yechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kana iwe uronga nezve kubereka mwana. Iwe haufanire kuve nepamuviri iwe paunenge uchitora selpercatinib. Kana iwe uri munhukadzi, iwe uchafanirwa kutora nhumbu yekubata usati watanga kurapwa uye kushandisa kuberekwa kudzivirira kudzivirira kubata panguva yekurapa kwako ne selpercatinib uye kwevhiki rimwe mushure meyako yekupedzisira dosi. Kana iwe uri murume, iwe neako mukadzi mukadzi munofanira kushandisa kuberekwa panguva yekurapa kwako ne selpercatinib uye kwevhiki imwe mushure meyako yekupedzisira dosi. Kana iwe kana mumwe wako mukava nepamuviri muchitora selpercatinib, danai chiremba wako nekukasira. Selpercatinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa iwe paunenge uchitora selpercatinib uye kwevhiki rimwe mushure mekupedzisira kwako.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi. Taura nachiremba wako nezve njodzi dzekutora selpercatinib.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora selpercatinib. Chiremba wako anogona kukuudza kuti usatore selpercatinib mazuva manomwe usati wavhiyiwa kana maitiro uye anokuudza iwe paunofanira kutanga kutora mushonga zvakare.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana iri mukati maawa matanhatu yeyako dosi inotevera, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing chirongwa. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Selpercatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• muromo wakaoma
• manyoka
• kuvimbiswa
• kusvotwa
• kurutsa
• kurwadziwa nemudumbu
• musoro
• kuneta
• kukosora
• mweya wekufema
• kuzvimba kwemaoko ako, makumbo, maoko, uye tsoka

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kurwadziwa muchikamu chepamusoro chepamusoro chedumbu; kupwanya kusingawanzo kana kubuda ropa; weti yakasviba; kana kuita yero kweganda uye ziso
• kurova kwemoyo
• dzungu kana hurema
• kufenda
• kukosora kana kurutsa ropa kana zvinhu zvinoita senge kofi nzvimbo; kubuda ropa kusingawanzo kana kupwanya, pink; tsvuku, kana yakasviba weti; kana tsvuku kana kunonoka kubuda hutumbu
• kusvotwa; kurutsa; mweya wekufema; tsandanyama; kushaya simba; pfari; kana kuzvimba kwemaoko nemakumbo
• fivha, mapundu, kana kurwadza kwemajoini kana tsandanyama

Selpercatinib inogona kukonzera kuti mapfupa amire kukura nekukurumidza munguva yevechidiki vachiri kukura. Taura nachiremba wemwana wako nezve njodzi dzekupa uyu mushonga kumwana wako.

Selpercatinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozotarisa kuwedzerwa kweropa rako nguva dzose uye agadzirise kumwe kuongororwa kwelebhu usati uye panguva yekurapwa kwako kuti utarise mhinduro yemuviri wako kune selpercatinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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