Thalidomide

Zvemukati

• Usati watora thalidomide,
• Thalidomide inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Njodzi yeakakomba, anotyisidzira hupenyu hurema hwekuzvarwa hunokonzerwa ne thalidomide.

Kune vanhu vese vanotora thalidomide:

Thalidomide haifanire kutorwa nevakadzi vane nhumbu kana vanogona kubata pamuviri vachitora mushonga uyu. Kunyangwe imwe chete dhizeti ye thalidomide inotorwa panguva yekuzvitakura inogona kukonzeresa kuremara kwekuzvara (matambudziko epanyama aripo mumwana pakuzvarwa) kana kufa kwemwana asati aberekwa. Chirongwa chinonzi Thalidomide REMS^® (yaimbozivikanwa seSystem yeThalidomide Dzidzo uye Kurondedzera Kuchengeteka [S.T.E.P.S.^®]) yakatenderwa neFood and Drug Administration (FDA) kuve nechokwadi chekuti vakadzi vane nhumbu havatore thalidomide uye kuti vakadzi havaite nhumbu pavanotora thalidomide. Vanhu vese vakapihwa thalidomide, kusanganisira varume nevakadzi vasingakwanise kubata nhumbu, vanofanirwa kunyoreswa neThalidomide REMS^®, Iva nechirwere che thalidomide kubva kuna chiremba uyo akanyoreswa neThalidomide REMS^®, uye uine mushonga unozadzwa kukhemisi iyo yakanyoreswa neThalidomide REMS^® kuitira kuti ugamuchire uyu mushonga.

Iwe unozofanirwa kuona chiremba wako mwedzi wega wega panguva yekurapa kwako kuti utaure nezve mamiriro ako uye chero mhedzisiro iwe yaungave uchisangana nayo. Pakushanya kwega kwega, chiremba wako anogona kukupa mushonga wekusvitsa kwemazuva makumi maviri nemasere ekurapa pasina zvekuzorodza. Iwe unofanirwa kuve uine uyu mushonga wakazadzwa mukati memazuva manomwe.

Usape ropa paunenge uchitora thalidomide uye kwevhiki ina mushure mekurapwa kwako.

Usagovana thalidomide nemumwe munhu, kunyangwe munhu anogona kunge aine zviratidzo zvakafanana zvauinazvo.

Kune vakadzi vanotora thalidomide:

Kana iwe uchigona kuve nepamuviri, iwe uchafanirwa kusangana nezvimwe zvinodikanwa panguva yekurapa kwako ne thalidomide. Iwe unofanirwa kuzadzisa izvi zvinodiwa kunyangwe iwe uine nhoroondo yekusagona kuve nepamuviri. Unogona kuregererwa kusangana nezvinodiwa izvi chete kana usati waenda kumwedzi (wakava nenguva) kwemwedzi makumi maviri nemana yakateedzana, kana kuti wakave nekuvhiyiwa (kuvhiyiwa kubvisa chibereko chako).

Iwe unofanirwa kushandisa maviri anogamuchirwa mafomu ekudzivirira kuberekwa kwemavhiki mana usati watanga kutora thalidomide, panguva yekurapwa kwako, uye kwevhiki ina mushure mekurapwa kwako. Chiremba wako anokuudza kuti ndedzipi nzira dzekudzivirira kuberekwa dzinogamuchirwa. Iwe unofanirwa kushandisa aya maviri maitiro ekudzivirira kuberekwa nguva dzese kunze kwekunge iwe uchigona kuvimbisa kuti hauzove nehukama hwepabonde nemunhurume kwemavhiki mana usati warapwa, panguva yekurapwa kwako, uye kwevhiki ina mushure mekurapwa kwako.

Mimwe mishonga inogona kukonzera kuti nhumbu dzekudzivirira kubata pamuviri dzisashande. Kana iwe uchironga kushandisa mahormone ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mapiritsi, majekiseni, zvindori, kana zvishandiso zvepamuviri) panguva yekurapa kwako ne thalidomide, udza chiremba wako nezvese mishonga, mavitamini, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. . Ive neshuwa yekutaura: griseofulvin (Grifulvin); mimwe mishonga yekurapa hutachiona hwehutachiwana hwevanhu (HIV) inosanganisira amprenavir (Agenerase), atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (muKaletra), nelfinavir (Viracept), ritonavir (Norvept) , muKaletra), saquinavir (Invirase), uye tipranavir (Aptivus); mimwe mishonga yekubatwa inosanganisira carbamazepine (Carbatrol, Equetro, Tegretol) uye phenytoin (Dilantin, Phenytek); modafinil (Provigil); penicillin; rifampin (Rimactane, Rifadin); rifabutin (Mycobutin); uye wort St. Mimwe mishonga yakawanda inogona kukanganisa chiito chehomoni yekudzivirira kubata pamuviri, saka ive shuwa kuudza chiremba wako ese mishonga yauri kutora kana kuronga kutora, kunyangwe iyo isinga oneke pane ino runyorwa.

Unofanirwa kuve nemiedzo miviri yekuzvitakura usati watanga kutora thalidomide. Iwe zvakare unofanirwa kuongororwa kuti une nhumbu murabhoritari pane dzimwe nguva panguva yekurapwa kwako. Chiremba wako anokuudza iwe nguva uye kupi kwaunofanira kuve nemiedzo iyi.

Regedza kutora thalidomide uye danaidza chiremba wako ipapo ipapo kana iwe uchifunga kuti une nhumbu, iwe unonoka, zvisina kujairika, kana kusuwa kwekuenda kumwedzi, une shanduko mukubuda ropa kwako kwekuenda kumwedzi, kana kuti unoita bonde usingashandise nzira mbiri dzekudzivirira kuberekwa. Mune zvimwe zviitiko, chiremba wako anokwanisa kukunyorera nhumbu dzekukurumidza ('mangwanani mushure mepiritsi') kudzivirira kubata pamuviri. Kana iwe ukava nepamuviri panguva yekurapa kwako, chiremba wako anodikanwa kufonera iyo FDA nemugadziri. Chiremba wako anozoitawo chokwadi chekuti unotaura nachiremba anonyanya kugadzirisa matambudziko panguva yekuzvitakura anogona kukubatsira kuita sarudzo dzakanakira iwe nemwana wako.

Kune varume vanotora thalidomide:

Thalidomide iripo mumbeu (fluid ine sperm inosunungurwa kubudikidza nepenishu panguva yegasm). Iwe unofanirwa kushandisa latex kana synthetic kondomu kana kudzivirira zvachose kusangana pabonde nemukadzi ane nhumbu kana kuti anogona kuve nepamuviri paunenge uchitora mushonga uyu uye kwevhiki ina mushure mekurapwa kwako. Izvi zvinodikanwa kunyangwe iwe uine vasectomy (kuvhiyiwa kudzivirira urume kubva mukusiya muviri wako uye zvichikonzera kubata). Udza chiremba wako nekukasira kana iwe wakamboita bonde zvisina dziviriro nemukadzi anokwanisa kuve nepamuviri kana kana iwe uchifunga chero chikonzero kuti mumwe wako ane nhumbu.

Usape urume kana urume paunenge uchitora thalidomide uye kwevhiki ina mushure mekurapwa kwako.

Ngozi yekugwamba kweropa:

Kana iwe uri kutora thalidomide kurapa akawanda myeloma (rudzi rwegomarara repfupa remongo), pane mukana wekuti iwe ugovandudza ropa rinovhara mumaoko ako, makumbo kana mapapu. Iyi njodzi yakakura kana thalidomide ichishandiswa pamwe chete nemamwe mishonga yemakemotherapy senge dexamethasone. Fonera chiremba wako nekukasira kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinzwa mweya wekufema; kana kurwadziwa muchipfuva. Chiremba wako anogona kunyorera anticoagulant ('ropa rakatetepa') kana aspirin kubatsira kumisa kugwamba kubva pakuumba panguva yekurapwa kwako ne thalidomide.

Taura nachiremba wako nezve njodzi dzekutora thalidomide.

Thalidomide inoshandiswa pamwe ne dexamethasone kurapa myeloma yakawanda muvanhu vakawanikwa munguva pfupi yapfuura vaine chirwere ichi. Inoshandiswawo yoga kana nemimwe mishonga yekurapa nekudzivirira zviratidzo zveganda erythema nodosum leprosum (ENL; zvikamu zvezvironda zveganda, fivhiri, uye kukuvara kwetsinga kunoitika kuvanhu vane hosha yaHansen [maperembudzi]). Thalidomide iri mukirasi yemishonga inonzi immunomodulatory agents. Inobata akawanda myeloma nekusimbisa immune system kurwisa cancer maseru. Inobata ENL nekuvhara chiitiko cheimwe yakasikwa zvinhu zvinokonzeresa kuzvimba.

Thalidomide inouya sekapuleti kutora nemuromo. Thalidomide inowanzo kutorwa nemvura kamwe chete pazuva panguva yekurara uye ingangoita 1 awa mushure mekudya kwemanheru. Kana iwe uri kutora thalidomide kurapa ENL, chiremba wako anogona kukuudza iwe kuti uitore kanopfuura kamwe pazuva, kweinenge 1 awa mushure mekudya. Tora thalidomide kwakatenderedza nguva imwechete (ma) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora thalidomide chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Chengeta iwo macapsule mune avo ekurongedza kusvikira wagadzirira kuatora. Usavhure macapsule kana kuabata zvakanyanya kupfuura zvakafanira. Kana ganda rako rikasangana nemakapisi akaputswa kana hupfu, geza nzvimbo iri pachena nesipo nemvura.

Kureba kwekurapwa kwako kunoenderana nekuti zviratidzo zvako zvinopindura sei thalidomide uye kuti zviratidzo zvako zvinodzoka here paunomira kutora mushonga. Chiremba wako angangoda kukanganisa kurapwa kwako kana kudzikisa dosi yako kana iwe ukawana mamwe mhedzisiro. Usarega kutora thalidomide usina kutaura nachiremba wako. Kana kurapwa kwako kwapera chiremba wako angangoderedza dosi rako zvishoma nezvishoma.

Thalidomide zvakare dzimwe nguva inoshandiswa kurapa mamwe mamiriro eganda anosanganisira kuzvimba uye kutsamwa. Inoshandiswawo kurapa mamwe matambudziko ehutachiona hwehutachiona hwehutachiona (hweHIV) senge aphthous stomatitis (mamiriro mune maronda mumuromo), manyoka ane hukama neHIV, hutachiona hunosanganisirwa neHIV, zvimwe hutachiona, uye Kaposi's sarcoma (rudzi yekenza yeganda). Thalidomide yakashandiswawo kurapa mamwe marudzi ekenza nemamota, kurasikirwa kwakanyanya kwevarwere vane hutachiona husina simba, chirwere chisingaperi chinopesana nechirwere (chinetso chinogona kuitika mushure mekuiswazve kwemongo wemapfupa umo izvo zvichangoburwa zvinhu zvinorwisa mupiki wekutora muviri), uye chirwere cheCrohn (mamiriro umo muviri unorwisa kumhara kwegayeti rekudya, zvichikonzera marwadzo, manyoka, kuonda uye kupisa muviri). Taura nachiremba wako nezve njodzi dzekushandisa mushonga uyu kune ako mamiriro.

Mushonga uyu dzimwe nguva unonyorerwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora thalidomide,

• udza chiremba wako uye wemishonga kana uri weergoria kune thalidomide kana chero mumwe mushonga.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa mune CHINOKOSHA CHENYENZO chikamu uye chero yeanotevera: antidepressants; barbiturates senge pentobarbital (Nembutal), phenobarbital, uye secobarbital (Seconal); chlorpromazine; didanosine (Videx); mishonga yekushushikana, chirwere chepfungwa, kana kubatwa; mamwe chemotherapy mishonga yekenza yakadai secisplatin (Platinol), paclitaxel (Abraxane, Taxol), uye vincristine; reserpine (Serpalan); kunyaradza; mapiritsi ekurara; uye zvinodzivirira. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove kana wakambove nehunhu hwehutachiona hwehutachiona (HIV), wakawana immunodeficiency syndrome (AIDS), mwero wakaderera wemasero machena eropa muropa rako, kana pfari.
• udza chiremba wako kana iwe uchiyamwisa.
• iwe unofanirwa kuziva kuti thalidomide inogona kukuwisira iwe. Usafambisa mota, shandisa michina, kana kuita zvimwe zvinhu zvinoda kuti uve wakasvinura zvizere kusvika waziva kuti mushonga uyu unokubata sei.
• bvunza chiremba wako nezve kushandiswa kwakachengeteka kwezvinwiwa zvinodhaka paunenge uchitora thalidomide. Doro rinogona kuita kuti mhedzisiro kubva thalidomide iwedzere.
• iwe unofanirwa kuziva kuti thalidomide inogona kukonzera dzungu, huremu husina musoro, uye kupera simba paunosimuka nekukurumidza kubva panzvimbo yekunyepa. Kuti ubatsire kunzvenga dambudziko iri, simuka pamubhedha zvishoma nezvishoma, uchizorora tsoka dzako pasi kwemaminetsi mashoma usati wasimuka.
• iwe unofanirwa kuziva kuti thalidomide iripo muropa rako uye mvura yemumuviri. Chero ani zvake angangosangana neaya mvura anofanirwa kupfeka magirovhosi kana kuwacha chero nzvimbo dzakavhurika dzeganda nesipo nemvura.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana iri isingasviki maawa gumi nemaviri kusvikira yako inotevera yakarongwa dhizaini, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Thalidomide inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kutsimwaira
• kuvhiringidzika
• kushushikana
• kushushikana kana kushanduka kwemanzwiro
• kunetseka kurara kana kuramba wakarara
• pfupa, mhasuru, kubatana, kana kurwadziwa musana
• kushaya simba
• musoro
• chinja mukuda kudya
• uremu hunochinja
• kusvotwa
• kuvimbiswa
• muromo wakaoma
• ganda rakaoma
• ganda rakachenuruka
• kuzunza kusingadzoreki nhengo yemuviri
• kuzvimba kwemaoko, tsoka, makumbo, kana makumbo ezasi
• kunetseka kuwana kana kuchengetedza erection

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• mapundu
• kuvava
• mikoko
• kubvaruka uye kubvisa ganda
• kuzvimba kwechiso, huro, rurimi, miromo, kana maziso
• hoarseness
• kunetseka kumedza kana kufema
• fivha, huro, chironda, chikosoro, kana zvimwe zviratidzo zvehutachiona
• inononoka kana kukurumidza kurova kwemoyo
• pfari

Thalidomide inogona kukonzera kukuvara kwemitsipa kunogona kuve kwakanyanya uye kusingaperi. Uku kukuvara kunogona kuitika chero nguva panguva kana mushure mekurapwa kwako. Chiremba wako achakuongorora nguva nenguva kuti aone kuti thalidomide yakanganisa sei hurongwa hwako hwemitsipa. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, rega kutora thalidomide uye udane chiremba wako nekukurumidza: chiveve, kurira, kurwadziwa, kana kupisa mumaoko nemakumbo.

Thalidomide inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari kuti atarise mhinduro yemuviri wako kune thalidomide.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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