Alirocumab (Yakakosha)
Zvemukati
- Zviratidzo zveAlirocumab (Yakakosha)
- Mirayiridzo yekushandiswa kweAlirocumab (Yakakosha)
- Side mhedzisiro yeAlirocumab (Yakakosha)
- Contraindications yeAlirocumab (Yakakosha)
- Kwokutenga Alirocumab (Yakakosha)
Alirocumab mushonga unoshanda kudzikisa cholesterol uye, nekudaro, kudzikisa njodzi yezvirwere zvemoyo zvakaita sekurwadziwa kwemoyo kana sitiroko, semuenzaniso.
Alirocumab iri nyore kushandisa mushonga unopinda majekiseni kuti ushandise kumba, uyo une anti-muviri unokwanisa kudzivisa kuita kwePSCK9, enzyme inodzivirira cholesterol yakaipa kubva mukubviswa muropa.
Zviratidzo zveAlirocumab (Yakakosha)
Alirocumab inoratidzirwa kumakesi evarwere vane cholesterol yakakwira yekuzvarwa nhaka kana yeavo cholesterol isingadzikire zvakakwana nekushandisa mishonga yakajairika, yakadai seSimvastatin kunyangwe padanho repamusoro rinotenderwa.
Mirayiridzo yekushandiswa kweAlirocumab (Yakakosha)
Kazhinji 1 jekiseni re75mg rinoratidzwa mazuva ese gumi neshanu, asi chiremba anogona kuwedzera dosi kusvika ku150mg mazuva ese gumi nemashanu kana zvichidikanwa kudzikisa huwandu hwecholesterol neanopfuura makumi matanhatu muzana. Iyo jekiseni inogona kuiswa subcutaneously muhudyu, dumbu kana ruoko, zvakakosha kushandura nzvimbo dzekushandisa.
Majekiseni anokwanisa kupihwa nemunhu kana muchengeti mushure mekutsanangurwa kwachiremba, mukoti kana wemishonga asi zviri nyore kuiswa nekuti ine chinyoreso chakazadzwa chisati chashandiswa kamwe chete.
Side mhedzisiro yeAlirocumab (Yakakosha)
Allergic maitiro akadai sekurumwa, nummular eczema uye vasculitis inogona kuoneka uye nzvimbo yejekiseni inogona kuzvimba uye kurwadza. Uye zvakare, zvakajairika kuti zviratidzo zvioneke muhunhu hwekufema sekuhotsira uye rhinitis.
Contraindications yeAlirocumab (Yakakosha)
Mushonga uyu hauna kuratidzwa kune vana nevachiri kuyaruka kusvika pamakore gumi nemasere ekuberekwa, pamwe nevakadzi vane nhumbu nekuti bvunzo dzekuchengetedza hadzina kuitwa mune dzino mamiriro. Izvo zvinopesana zvakare panguva yekuyamwisa nekuti inopfuura nemukaka wemukaka,
Kwokutenga Alirocumab (Yakakosha)
Alirocumab imushonga une zita rekutengeserana rePrueent, urikuedzwa nemarabhoritari eSanofi neRegeneron, uye hausati wawanikwa kutengeswa kuruzhinji.
Kazhinji, zvakajairika mishonga yecholesterol, senge simvastatin, inowedzera kugadzirwa kwePSCK9 uye, nekudaro, mushure menguva yakati, mushonga wacho unobva watadza kushanda mukuderedza cholesterol. Nekudaro, Alirocumab inogona kushandiswa kupedzisa kurapwa nemhando iyi yemishonga, pamusoro pekukwanisa kushandiswa senzira imwechete yekurapa kune varwere vasingakwanise kudzikisa cholesterol nemishonga yakajairika.
Tarisa uone maitiro ekurapa ekurapa kudzora ropa cholesterol:
- Mushonga weCholesterol
- Cholesterol-kudzikisa kudya