Baricitinib: ndeyei iyo, kuitora sei uye mhedzisiro

Zvemukati

• Chii ichochi
• Baricitinib inokurudzirwa kurapwa kwe COVID-19?
• Sei kutora
• Zvinogona kuitika mhedzisiro
• Ndiani asingafanire kushandisa

Baricitinib mushonga unoderedza mhinduro yemasoja ekudzivirira muviri, kudzikisira kuita kwemaenzyme anokurudzira kuzvimba uye kuoneka kwekukuvara kwemajoini mumatambudziko erheumatoid arthritis. Nenzira iyi, uyu mushonga unokwanisa kudzikisa kuzvimba, kubvisa zviratidzo zvechirwere sekurwadziwa uye kuzvimba kwemajoini.

Mushonga uyu unobvumidzwa naAnvisa kuti ushandiswe murheumatoid arthritis, ine zita rekutengeserana Olumiant uye inogona kutengwa mumafamasi chete nemushonga, muchimiro chemapiritsi e2 kana 4 mg.

Chii ichochi

Baricitinib inoratidzirwa kudzikisa marwadzo, kuomarara uye kuzvimba kwerheumatoid arthritis, mukuwedzera pakudzora kufambira mberi kwekukuvara kwepfupa uye kwemajoini.

Mushonga uyu unogona kushandiswa wega kana musanganiswa nemethotrexate, pakurapa rheumatoid arthritis.

Baricitinib inokurudzirwa kurapwa kwe COVID-19?

Baricitinib inongobvumidzwa muUnited States kurapa hutachiona neiyo nyowani inofungidzirwa kuti coronavirus kana kusimbiswa neongororo yeLabhoritari, painoshandiswa pamwe chete nere remesivir, inova iyo antiviral. Remdesivir inotenderwa naAnvisa yezvidzidzo zvekuyedza zveCovid-19.

Zvimwe zvidzidzo zvakaratidza kuti uyu mushonga unogona kubatsira kuvharira coronavirus kupinda mumaseru uye kudzikamisa nguva yekufa uye kufa mune zvine mwero kusvika kumatambudziko akaoma, kune vanhu vakuru vari muchipatara nevana vane makore anopfuura maviri ekuberekwa vanoda oxygen, kufefetedza michina kana oxygenation neyekunze membrane. Tarisa uone zvese zvinogamuchirwa uye zvekudzidza zvinodhaka zveCovid-19.

Sekureva kwaAnvisa, kutengwa kwebaricitinib ku pharmacy kuchiri kubvumidzwa, asi chete kune vanhu vane mishonga yekurapwa ye rheumatoid arthritis.

Sei kutora

Baricitinib inofanirwa kutorwa nemuromo maererano nezano rekurapa, kamwe pazuva, pamberi kana mushure mekudya.

Hwendefa racho rinofanira kugara richitorwa panguva imwe chete, asi kana paine kukanganwa, muyero unofanirwa kutorwa nekukurumidza kana uchinge warangarira wozogadzirisa iwo marongero zvinoenderana nedosi yekupedzisira iyi, uchienderera mberi nekurapwa zvinoenderana nenguva itsva dzakarongwa. Usapeta kaviri muyero wacho kuti uwane dhosi yakanganwika.

Usati watanga kurapwa ne baricitinib, chiremba anofanirwa kukurudzira kuti uongororwe kuti uve nechokwadi chekuti hauna chirwere chetibhii kana zvimwe zvirwere.

Zvinogona kuitika mhedzisiro

Mimwe yemhedzisiro inowanzoitika panguva yekurapwa ne baricitinib ndeyekugumbuka kunoitika kuzvinhu zvemapiritsi, kuda kurutsa kana kuwedzera njodzi yehutachiona hunosanganisira tibhii, fungal, bhakitiriya kana hutachiona hutachiona hwakadai sehepe simplex kana herpes zoster.

Uye zvakare, baricitinib inogona kuwedzera njodzi yekuvandudza lymphoma, yakadzika vein thrombosis kana pulmonary embolism.

Zvinokurudzirwa kurega kushandisa uye kutsvaga rubatsiro rwechiremba nekukurumidza kana zviratidzo zvekurwara kwakanyanya kune baricitinib zvikaonekwa, sekuoma kufema, kunzwa kwekusimba pahuro, kuzvimba mumuromo, rurimi kana kumeso, kana mikoko, kana iwe ukatora. baricitinib mumadhihosi akakura kupfuura iwo akakurudzirwa kutevedzera zviratidzo nezviratidzo zvemhedzisiro.

Ndiani asingafanire kushandisa

Baricitinib haifanire kushandiswa nevakadzi vane nhumbu kana vanoyamwisa, mune chirwere chetibhii kana hutachiona hutachiona hwakadai secandidiasis kana pneumocystosis.

Mushonga uyu unofanirwa kushandiswa nekuchenjerera kune vanhu vane matambudziko ekugwamba kweropa, kusanganisira vechikuru, vanhu vakafutisa, vanhu vane nhoroondo yetrombosis kana embolism kana vanhu vanozove nerumwe rudzi rwekuvhiyiwa uye vanofanirwa kuve vasina simba. Pamusoro pezvo, kungwarira kunofanirwa kuitwawo kune vanhu vane hurema hwechiropa kana hweitsvo, kupererwa neropa kana kune vanhu vane immune system isina simba, vangangoda kuchinjirwa nachiremba.