Chii chinonzi chimerism, mhando uye maitiro ekuziva

Zvemukati

• Mhando dze chimerism
• 1. Natural chimerism
• 2. Chakagadzirwa chimerism
• 3. Microquimerismo
• 4. Twin chimera
• Ungaziva sei

Chimerism rudzi rwechinhu chisingawanzoitika pakuchinja kwemajini, uko kungave kuri kwechisikigo, kunoitika panguva yekuzvitakura, semuenzaniso, kana kuve nekuda kwehematopoietic stem sero kuisirwa, umo masero eakaiswa masero evanopa. inonwiwa neiye anogamuchira, pamwe nekuvapo-pamwe chete kwemasero ane akasiyana magene mafaera.

Inofungidzirwa chimerism apo kuvepo kwevaviri kana kupfuura vanhu vemageneti akasarudzika nemagene akasiyana akasimbiswa, zvakasiyana nezvinoitika mukushambadzira, umo kunyangwe hazvo huwandu hwemasero hwakamira zvakasiyana, ivo vane mabviro akafanana. Dzidza zvakawanda nezve mosaicism.

Mhando dze chimerism

Chimimumu haina kujairika pakati pevanhu uye inogona kuoneka zviri nyore mumhuka. Nekudaro zvichiri kuitika kuti kune chimerism pakati pevanhu, mhando huru dziri:

1. Natural chimerism

Natural chimerism inoitika kana mazai maviri kana anopfuura achibatana achiumba rimwe. Nekudaro, mucheche akaumbwa nezviviri kana kupfuura zvakasiyana majini zvigadzirwa

2. Chakagadzirwa chimerism

Zvinoitika kana munhu achinge awedzerwa kuwedzerwa ropa kana kupfuudzwa kwemongo wemapfupa kana hematopoietic stem masero kubva kune mumwe munhu, nemasero evanopa achitora muviri. Aya mamiriro aive akajairika munguva yakapfuura, zvisinei nhasi mushure mekuiswazve munhu wacho anoteverwa uye anoita mamwe marapirwo anotadzisa kunyudzwa kwekusingaperi kwemasero evanopa, kuwedzera pakuona kugamuchirwa kuri nani kwekuiswazve nemuviri.

3. Microquimerismo

Rudzi urwu rwechimbichimbi rwunoitika panguva yekuzvitakura, umo mukadzi anopinza mamwe maseru kubva muchibereko kana fetus inotora masero kubva kuna amai, zvichikonzera maviri akasiyana magene.

4. Twin chimera

Rudzi rwechimbichimbi chinoitika kana panguva yekuzvitakura kwemapatya, rimwe fetus rinofa uye rimwe fetus rinotora mamwe masero aro. Nekudaro, mwana anozvarwa ane zvinhu zvake zvechiberekero uye nemagene emunin'ina wake.

Ungaziva sei

Iyo chimerism inogona kuzivikanwa kuburikidza nehumwe hunhu hunogona kuratidzwa nemunhu senzvimbo dzemuviri dzine hushoma kana kushoma pigment, maziso ane mavara akasiyana, kuitika kwezvirwere zve autoimmune zvine chekuita neganda kana huta uye nehukama, mune izvo kusiana kwehunhu hwepabonde uye chromosomal maitiro, izvo zvinoita kuti zviome kuziva munhu wacho sewemurume kana mukadzi.

Uye zvakare, chimerism inoonekwa kuburikidza nemuyedzo inoongorora magene, DNA, uye kuvepo kwemaviri kana anopfuura mapara eDNA mumasero matsvuku eropa, semuenzaniso, anogona kusimbiswa. Uye zvakare, mune chimerism mushure mehematopoietic stem cell yekuisirwa, zvinokwanisika kuti uone kushandurwa uku kuburikidza nekuongorora kwemajini kunoongorora mamaki anozivikanwa seStrs, ayo anokwanisa kusiyanisa masero eanogamuchira neanopa.