10 Mazwi Aunofanira Kuziva: Isiri-diki Cell Lung Cancer

Zvemukati

• Yakarongwa kufa-ligand 1 (PD-L1)
• Epidermal kukura chinhu chinogamuchira (EGFR)
• T790M shanduko
• Tyrosinse-kinase inhibitor (TKI) kurapa
• KRAS shanduko
• Anaplastic lymphoma kinase (ALK) kuchinja
• Adenocarcinoma
• Squamous sero (epidermoid) carcinoma
• Makuru masero (asina kukamurwa) carcinoma
• Immunotherapy

Mhedziso

Kunyangwe iwe kana mudiwa wako waonekwa, isiri-diki kenza yemapapu kenza (NSCLC) uye mazwi mazhinji ane chekuita nazvo anogona kutyisa. Kuedza kufambidzana neese mazwi ayo chiremba anokuudza iwe zvinogona kuve zvakaoma, kunyanya mukuwedzera kune iyo yemanzwiro mhedzisiro yekenza.

Heano mazwi gumi ekuziva nezve NSCLC iwe yaungasangane nayo paunenge uchiita nzira yako kuburikidza nekuyedza uye kurapwa.

Yakarongwa kufa-ligand 1 (PD-L1)

PD-L1 kuyera kuyera kushanda kweimwe yakanangwa marapirwo (kazhinji immune-mediated) kune avo vane NSCLC. Izvi zvinobatsira vanachiremba kukurudzira nzira dzakanakisa dzekurapa-mutsara wechipiri.

Dzokera kubhangi rezwi

Epidermal kukura chinhu chinogamuchira (EGFR)

EGFR iri geni iro rinobatanidzwa mukukura kwemasero uye kupatsanuka. Kuchinja kweiyi geni kunoenderana nekenza yemapapu. Kusvikira hafu yezviitiko zvese zvegomarara remapapu zvine geni mutation iripo.

Dzokera kubhangi rezwi

T790M shanduko

T790M ishanduko yeEGFR inoonekwa munenge hafu yezviitiko zvese zvinopesana nemishonga NSCLC makesi. Iko kushanduka kunoreva kuti pane shanduko mumaamino acids, uye zvinokanganisa maitiro anoita mumwe munhu kurapwa.

Dzokera kubhangi rezwi

Tyrosinse-kinase inhibitor (TKI) kurapa

TKI kurapa imhando yekurapa kwakanangwa kweNSCLC inovhara chiitiko cheEGFR, icho chinogona kuchengetedza maseru ekenza kubva mukukura.

Dzokera kubhangi rezwi

KRAS shanduko

Iyo KRAS gene inobatsira kudzora kupatsanurwa kwesero. Icho chikamu cheboka remajini anonzi oncogenes. Panyaya yekuchinja, inogona kushandura maseru ane hutano kuita cancer. KRAS gene shanduko inoonekwa mune ingangoita gumi neshanu kusvika makumi maviri muzana muzana yematambudziko ekenza yemapapu.

Dzokera kubhangi rezwi

Anaplastic lymphoma kinase (ALK) kuchinja

Iko ALK mutchinzo kugadziriswazve kweALK geni. Iyi shanduko inoitika mune angangoita mashanu muzana eNSCLC kesi, kazhinji kune avo vane adenocarcinoma subtype yeNSCLC. Iko kushanduka kunokonzera maseru emukenza emapapu kukura nekupararira.

Dzokera kubhangi rezwi

Adenocarcinoma

Adenocarcinoma chidimbu cheNSCLC. Iyo inowanzo kukura zvishoma nezvishoma kupfuura mamwe marudzi ekenza yemapapu, asi izvi zvinosiyana. Ndiyo mhando yakajairika yekenza yemapapu inoonekwa kune vasingasvuti.

Dzokera kubhangi rezwi

Squamous sero (epidermoid) carcinoma

Squamous cell carcinoma chidimbu cheNSCLC. Vanhu vazhinji vane iyi subtype yekenza yemapapu vane nhoroondo yekusvuta. Gomarara rinotanga mumaseru anokatyamadza, ayo ari maseru ari mukati memapapu mweya.

Dzokera kubhangi rezwi

Makuru masero (asina kukamurwa) carcinoma

Yakakura sero carcinoma idiki reNSCLC iro rinogona kuoneka mune chero chikamu chemapapu. Kazhinji zvinonetsa kurapa nekuti inokura uye inopararira nekukurumidza. Iyo inosvika gumi kusvika gumi muzana muzana emakenza emapapu.

Dzokera kubhangi rezwi

Immunotherapy

Immunotherapy mushonga mutsva wecancer unoshandisa immune system yemunhu kubatsira muviri kurwisa cancer maseru. Inogona kushandiswa kurapa mamwe mafomu eNSCLC, kunyanya kune vanhu vane gomarara rakadzoka mushure memakemikari ekurapa kana kumwe kurapwa.

Dzokera kubhangi rezwi