Ankylosing spondylitis

Ankylosing spondylitis (AS) ndiyo isingagumi fomu yemajoini. Inonyanya kukanganisa mapfupa nemajoini pazasi pemuzongoza uko inosangana nehudyu. Aya majoini anogona kuzvimba uye kuzvimba. Nekufamba kwenguva, mapfupa emusana akakanganiswa anogona kubatana.

AS ndiye nhengo huru yemhuri yemhando dzakafanana dzeArthritis inonzi spondyloarthritis. Dzimwe nhengo dzinosanganisira psoriatic arthritis, arthritis yehutachiona hwechirwere chirwere uye reactive arthritis. Mhuri yeArthritis inoita kunge yakajairika uye inobata inosvika munhu mumwe muvanhu zana.

Chikonzero cheAS hachizivikanwe. Majini anoita kunge anoita basa. Vazhinji vanhu vane AS vane chokwadi cheiyo HLA-B27 geni.

Chirwere ichi chinowanzotanga pakati pemakore makumi maviri nemakumi mana, asi chinogona kutanga makore asati asvika gumi. Chinobata vanhurume vakawanda kudarika vanhukadzi.

AS inotanga nemarwadzo ekudzokera kumashure anouya uye anoenda. Kutambudzika kwekudzokera shure kunovepo kazhinji kazhinji sezvo mamiriro achienderera.

• Marwadzo uye kuomarara zvakanyanyisa usiku, mangwanani, kana paunenge usingaite basa. Iko kusagadzikana kunogona kukumutsa iwe kubva kuhope.
• Marwadzo anowanzo kuve nani nebasa kana kurovedza muviri.
• Kutambudzika kwekudzokera shure kunogona kutanga pakati pepelvis uye musana (sacroiliac majoini). Nekufamba kwenguva, zvinogona kusanganisira zvese kana chikamu chemuzongoza.
• Musana wako wezasi unogona kushomeka kushanduka. Nekufamba kwenguva, unogona kumira wakabatirira mberi chinzvimbo.

Zvimwe zvikamu zvemuviri wako zvinogona kukanganiswa zvinosanganisira:

• Majoini emapendekete, mabvi uye makumbo, anogona kunge achizvimba uye achirwadza
• Iwo majoini ari pakati pembabvu dzako nepfupa, kuitira kuti usakwanise kuwedzera chifuva chako zvizere
• Ziso, rinogona kunge rakazvimba uye kutsvuka

Kuneta zvakare chiratidzo chakajairika.

Zviratidzo zvishoma zvinozivikanwa zvinosanganisira:

• Zvishoma fever

AS inogona kuitika nemamwe mamiriro, akadai se:

• Psoriasis
• Ulcerative colitis kana chirwere cheCrohn
• Kudzokororazve kana kusingaperi kwemaziso kuzvimba (iritis)

Miedzo inogona kusanganisira:

• CBC
• ESR (chiyero chekuputika)
• HLA-B27 antigen (iyo inoona geni rakabatana ne ankylosing spondylitis)
• Rheumatoid factor (iyo inofanirwa kunge isina kunaka)
• X-ray yemuzongoza uye chiuno
• MRI yemuzongoza uye pelvis

Mutapi wako wezvehutano anogona kupa mishonga yakadai seNSAIDs kudzikisira kuzvimba nekurwadziwa.

• Dzimwe NSAID dzinogona kutengwa kupfuura-the-counter (OTC). Izvi zvinosanganisira aspirin, ibuprofen (Advil, Motrin), uye naproxen (Aleve, Naprosyn).
• Dzimwe NSAID dzinotsanangurwa nemupi wako.
• Taura nemupi wako kana wemishonga pamberi pezuva nezuva kushandisa-kwenguva refu kweanopfuura-the-counter NSAID.

Iwe unogona zvakare kuda mishonga yakasimba kudzora kurwadziwa nekuzvimba, senge:

• Corticosteroid kurapa (senge prednisone) inoshandiswa kwenguva pfupi
• Sulfasalazine
• Biologic TNF-inhibitor (senge etanercept, adalimumab, infliximab, certolizumab kana golimumab)
• Iyo biologic inhibitor ye IL17A, secukinumab

Kuvhiya, kwakadai sekumisikidza hudyu, kunogona kuitwa kana kurwadziwa kana kukuvara kwemajoini kwakanyanya.

Maekisesaizi anogona kubatsira kuvandudza mamiriro uye kufema. Kunyepa flat kumusana kwako husiku kunogona kukubatsira kuti urambe wakamira zvakanaka.

Nzira yechirwere ichi yakaoma kufungidzira. Nekufamba kwenguva, zviratidzo nezviratidzo zveAS flareup (kudzokazve) uye kunyarara pasi (kuregererwa). Vanhu vazhinji vanokwanisa kushanda nemazvo kunze kwekunge vaine zvakawanda zvakakanganisa muhudyu kana musana. Kujoinha boka rekutsigira revamwe vane dambudziko rakafanana kunogona kubatsira.

Kurapa neNSAIDS kunowanzo deredza marwadzo uye kuzvimba. Kurapa neTNF inhibitors kutanga kwechirwere kunoratidzika kunonoka kufambira mberi kwespinal arthritis.

Kazhinji, vanhu vane ankylosing spondylitis vanogona kunge vaine matambudziko ne:

• Psoriasis, chirwere chisingaperi cheganda
• Kuzvimba muziso (iritis)
• Kuzvimba mumatumbo (colitis)
• Abnormal moyo mutinhimira
• Kuora kana kuunyana kwemapapu emapapu
• Kuora kana kuomarara kweaortic moyo vharuvhu
• Spinal cord kukuvara mushure mekudonha

Fonera mupiki wako kana:

• Iwe une zviratidzo zve ankylosing spondylitis
• Iwe une ankylosing spondylitis uye unovandudza zviratidzo zvitsva panguva yekurapa

Spondylitis; Spondyloarthritis; HLA - Spondylitis

• Skeletal musana
• Cervical spondylosis

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Inman RD. Iyo spondyloarthropathies. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsama 249.

van der Linden S, Brown M, Gensler LS, Kenna T, Maksymowych WP, Taylor WJ. Ankylosing spondylitis uye mamwe mafomu eaxial spondyloarthritis. Mune: Firestein GS, Budd RC, Gabriel SE, Koretzky GA, McInnes IB, O'Dell JR, eds. Firestein & Kelly's Bhuku reRheumatology. 11th ed. Philadelphia, PA: Elsevier; 2021: chits. 80.

Wadhi MM, Deodhar A, Gensler LS, et al. 2019 Kwidziridzo yeAmerican College yeRheumatology / Spondylitis Association yeAmerica / Spondyloarthritis Kutsvaga uye Kurapa Network Kurudziro yekurapa ankylosing spondylitis uye nonradiographic axial spondyloarthritis. Arthritis Kuchengeta Res (Manhattan). 2019; 71 (10): 1285-1299. PMID: 31436026 pubmed.ncbi.nlm.nih.gov/31436026/.

Werner BC, Feuchtbaum E, Shen FH, Samartzis D. Ankylosing spondylitis yemuzongoza. Mune: Shen FH, Samartzis D, Fessler RG, eds. Chinyorwa cheCervical Spine. Philadelphia, PA: Elsevier Saunders; 2015: chitsiko 28.