Ovarian kuwanda kweiyo androgens

Ovarian kuwanda kwekuwedzera kwe androgens mamiriro umo maovari anoita testosterone yakawandisa. Izvi zvinotungamira mukuvandudzwa kwehunhu hwechirume mumukadzi. Androgens anobva kune mamwe mativi emuviri anogona zvakare kukonzera hunhu hwechirume kukura muvakadzi.

Mune vakadzi vane hutano, maovari uye adrenal gland anogadzira angangoita 40% kusvika 50% ye testosterone yemuviri. Tumors yeiyo ovaries uye polycystic ovary syndrome (PCOS) inogona zvese kukonzera kuwanda uyerogen kugadzirwa.

Cushing chirwere idambudziko nepituitary gland inotungamira kune yakawandisa macorticosteroids. Corticosteroids inokonzeresa kuchinja kwemuviri wechirume muvakadzi. Mamota mune adrenal glands anogona zvakare kukonzera kuwanda kugadzirwa kwe androgens uye kunogona kutungamira kune echirume muviri hunhu muvakadzi.

Yakakwira mazinga e androgens mune mukadzi anogona kukonzera:

• Acne
• Shanduko muhunhu hwevakadzi
• Kuderera muhukuru hwezamu
• Wedzera bvudzi remuviri mune yechirume pateni, senge pachiso, chin, uye mudumbu
• Kushaikwa kwekuenda kumwedzi (amenorrhea)
• Ganda rine mafuta

Shanduko idzi dzinogona zvakare kuitika:

• Wedzera kukura kweiyo clitoris
• Kudzika kwezwi
• Wedzera mumhasuru
• Kucheka kwebvudzi uye kurasikirwa nevhudzi kumberi kweganda kumativi ese emusoro

Mutapi wako wezvehutano achaita bvunzo dzepanyama. Chero ropa uye yekufungidzira bvunzo zvakarairwa zvinoenderana nezviratidzo zvako, asi zvinogona kusanganisira:

• 17-hydroxyprogesterone bvunzo
• ACTH bvunzo (isina kujairika)
• Cholesterol ropa kuongororwa
• CT scan
• DHEA kuongorora ropa
• Glucose bvunzo
• Insulin bvunzo
• Pelvic ultrasound
• Prolactin bvunzo (kana nguva dzichiuya zvishoma kana kusatomboita)
• Testosterone bvunzo (ese emahara uye akazara testosterone)
• TSH bvunzo (kana paine kurasikirwa bvudzi)

Kurapa kunoenderana nedambudziko riri kukonzera kuwedzerwa uyerogen kugadzirwa. Mishonga inogona kupihwa kudzikisa kugadzirwa kwebvudzi mune vakadzi vane bvudzi remuviri rakawandisa, kana kudzora kutenderera kwemwedzi. Mune zvimwe zviitiko, kuvhiyiwa kunogona kudikanwa kuti ubvise ovari kana adrenal bundu.

Kurapa kubudirira kunoenderana nechikonzero chekuwandisa uyerogen kugadzirwa. Kana mamiriro acho ari kukonzerwa nebundu reovarian, kuvhiyiwa kubvisa bundu kunogona kugadzirisa dambudziko. Mazhinji mamota emazai haana kenza (benign) uye haazodzoke mushure mekunge abviswa.

Mune polycystic ovary syndrome, anotevera matanho anogona kudzora zviratidzo zvinokonzerwa neepamusoro uyerogenji mazinga:

• Kuchenjerera kuongorora
• Kuonda
• Kuchinja kwekudya
• Mishonga
• Kugara uchirovedza muviri zvine simba

Kushaya mbereko uye matambudziko panguva yekuzvitakura anogona kuitika.

Vakadzi vane polycystic ovary syndrome vanogona kunge vari panjodzi yekuwedzera ye:

• Chirwere cheshuga
• Kuwedzera kweropa
• Cholesterol yakakwira
• Kufutisa
• Kenza yechibereko

Vakadzi vane polycystic ovary syndrome vanogona kudzora shanduko yavo yenguva refu yematambudziko nekuchengetedza huremu hwakajairika kuburikidza nekudya zvine hutano uye kugara uchirovedza muviri.

• Kuwedzeredza mazai
• Follicle kuvandudza

Bulun SE. Physiology uye hutachiona hwevakadzi hwekubereka axis. Mune: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Chinyorwa cheEndocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020: chits. 17.

Huddleston HG, Quinn M, Gibson M. Polycystic ovary syndrome uye hirsutism. Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chitsiko 567.

Lobo RA. Hyperandrogenism uye androgen yakawandisa: physiology, etiology, kusiyanisa kuongororwa, manejimendi. Mune: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Yakakwana Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017: chitsiko 40.

Rosenfield RL, Barnes RB, Ehrmann DA. Hyperandrogenism, hirsutism, uye polycystic ovary syndrome. Muna: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Vakuru uye Chiremba. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 133.