CSF oligoclonal banding

CSF oligoclonal banding bvunzo yekutarisa mapuroteni ane chekuita nekuzvimba mu cerebrospinal fluid (CSF). CSF ndiyo yakajeka mvura inoyerera munzvimbo yakatenderedza musana wepelinha uye huropi.

Oligoclonal mabhendi mapuroteni anonzi immunoglobulins. Kuvapo kweaya mapuroteni kunoratidza kuzvimba kwenzvimbo yepakati yetsinga. Kuvapo kwemaoligoclonal mabhendi kunogona kunongedza kuongororwa kwe multiple sclerosis.

Muenzaniso we CSF unodiwa. Lumbar puncture (musana tap) ndiyo nzira yakajairika yekutora iyi sampuro.

Dzimwe nzira dzekuunganidza CSF hadziwanzoshandiswa, asi dzinogona kukurudzirwa mune dzimwe nguva. Zvinosanganisira:

• Kubviswa kwetangi
• Ventricular kubaya
• Kubviswa kweCSF kubva pombi iyo yatove muCSF, senge shunt kana ventricular drain.

Mushure mekunge sampuro yatorwa, inotumirwa kune lab yekuyedzwa.

Bvunzo iyi inobatsira kutsigira kuongororwa kwe multiple sclerosis (MS). Zvisinei, hazvisimbisi kuongororwa. Oligoclonal mabhendi muCSF anogona zvakare kuonekwa mune zvimwe zvirwere zvakaita se:

• Systemic lupus erythematosus
• Utachiona hwehutachiona hwehutachiona hweHIV (hutachiona hweHIV)
• Kurohwa

Kazhinji, rimwe kana kwete mabhendi anofanirwa kuwanikwa muCSF.

Ongorora: zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pema laboratories akasiyana. Taura nemupi wako wezvehutano nezve zvinorehwa nemimwe miedzo yako.

Iyi mienzaniso iripamusoro inoratidza zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Mamwe marabhoritari anoshandisa zviyero zvakasiyana kana anogona kuyedza mienzaniso dzakasiyana.

Kune maviri kana anopfuura mabhande anowanikwa muCSF uye kwete muropa. Ichi chingave chiratidzo che multiple sclerosis kana kumwe kuzvimba.

Cerebrospinal fluid - immunofixation

• CSF oligoclonal banding - akateedzana
• Lumbar puncture (musana tap)

Deluca GC, Griggs RC. Kusvika kumurwere ane chirwere chetsinga. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chap 368.

Karcher DS, McPherson RA. Cerebrospinal, synovial, serous muviri mvura, uye mamwe maenzaniso. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chitsiko 29.