Munyori: Gregory Harris
Zuva Rekusika: 8 Kubvumbi 2021
Gadziridza Zuva: 21 Mbudzi 2024
Anonim
The Mechanism of Action (MOA)
Vhidhiyo: The Mechanism of Action (MOA)

Zvemukati

Deutetrabenazine inogona kuwedzera njodzi yekuora mwoyo kana kufunga kuzviuraya (kufunga nezvekuzvikuvadza kana kuzviuraya kana kuronga kana kuyedza kuzviita) muvanhu vane chirwere cheHuntington (chirwere chakagarwa nhaka chinokonzera kuparara kunofambira mberi kwemasero etsinga muuropi). Udza chiremba wako kana iwe wakambove nekuora mwoyo uye kana iwe wakambove kana wakambofunga nezvekukuvadza kana kuzviuraya iwe. Kana iwe uine chirwere chaHuntington uye wakaora mwoyo kana uine pfungwa dzekuzviuraya, chiremba wako angangokuudza kuti usatore deutetrabenazine. Iwe, mhuri yako, kana muchengeti unofanira kufonera chiremba wako ipapo kana iwe ukaona chero cheanotevera zviratidzo: kutsva kana kuwedzera kuora mwoyo, pfungwa dzekuzvikuvadza kana kuzviuraya kana kuronga kana kuyedza kuzviita, kunetseka zvakanyanya, kushungurudzika, kunetseka kurara kana kugara wakarara, hasha kana hunhu, kusagadzikana, kuita usingafunge, kusagadzikana kwakanyanya, kushushikana, kushanduka muhuremu hwemuviri, kurasikirwa nekufarira kudyidzana munharaunda, kunetseka kuteerera, kana chero imwe shanduko isina kujairika mumaitiro. Iva nechokwadi chekuti mhuri yako kana muchengeti anokutarisa nguva dzose uye anoziva kuti ndezvipi zviratidzo zvingave zvakakomba kuitira kuti vagone kufonera chiremba kana iwe usingakwanise kutsvaga kurapwa uri wega.


Chengetedza zvese zvakagadzwa nachiremba wako. Chiremba wako angangoda kutaura newe nezve hutano hwako hwepfungwa paunenge uchitora mushonga uyu.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa ne deutetrabenazine uye pese paunozadza tsamba yako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Deutetrabenazine inoshandiswa kurapa chorea (kufamba kamwe kamwe kwausingakwanise kudzora) kunokonzerwa nechirwere cheHuntington (chirwere chakagarwa nhaka chinokonzera kuparara kunofambira mberi kwemasero etsinga muuropi). Iyo zvakare inoshandiswa kurapa tardive dyskinesia (isingadzoreki kufamba kwechiso, rurimi, kana zvimwe zvikamu zvemuviri). Deutetrabenazine iri mukirasi yemishonga inonzi vesicular monoamine transporter 2 (VMAT2) inhibitors. Inoshanda nekushandura mashandiro ezvimwe zvinhu zvakasikwa muuropi zvinokanganisa tsinga nemhasuru.


Deutetrabenazine inouya sehwendefa kutora nemuromo. Kune varwere vane chirwere cheHuntington, inowanzo kutorwa nechikafu kamwe chete pazuva pakutanga uye ndokuzowedzerwa kusvika kaviri pazuva. Kune varwere vane tardive dyskinesia, inowanzo kutorwa nechikafu kaviri pazuva. Tora deutetrabenazine panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora deutetrabenazine chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Chiremba wako angangotanga iwe padosi yakaderera yedheutetrabenazine uye zvishoma nezvishoma wedzera yako dosi, kwete kanopfuura kamwe pasvondo.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.


Usati watora deutetrabenazine,

  • udza chiremba wako uye wemishonga kana uri weergoria kune deutetrabenazine, chero mimwe mishonga, kana chero chipi chinosanganiswa mumapiritsi e deutetrabenazine. Inoshanda nekushandura chiitiko cheimwe yakasarudzika zvinhu muuropi. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uri kutora reserpine, tetrabenazine (Xenazine), valbenazine (Ingrezza), kana monoamine oxidase (MAO) inhibitor senge isocarboxazid (Marplan), linezolid (Zyvox), methylene bhuruu, phenelzine (Nardil), selegiline (Eldeprylline , Emsam, Zelapar), uye tranylcypromine (Parnate), kana kana iwe wakamira kutora monoamine oxidase inhibitor mukati memavhiki maviri apfuura kana kumira kutora reserpine mumazuva makumi maviri apfuura. Chiremba wako angangokuudza kuti haufanire kutora deutetrabenazine.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero yeanotevera: mishonga yekushushikana; mishonga yekudzvinyirira senge bupropion (Aplenzin, Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem, Selfemra), uye paroxetine (Brisdelle, Paxil, Pexeva); antipsychotic yakadai seklorpromazine, haloperidol (Haldol), olanzapine (Zyprexa), quetiapine (Seroquel), risperidone (Risperdal), thioridazine, uye ziprasidone (Geodon); mimwe mishonga yekurova kwemoyo zvisina kujairika senge amiodarone (Nexterone, Pacerone), procainamide, quinidine (muNuedexta), uye sotalol (Betapace, Sorine, Sotylize); moxifloxacin (Avelox); mishonga yekubatwa; sedatives, kurara mapiritsi, kana zvidzikisira. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe une chirwere chechiropa. Chiremba wako angangokuudza kuti usatore deutetrabenazine.
  • udza chiremba wako kana iwe kana wakambove nerefu QT syndrome (mamiriro anowedzera mukana wekuvandudza kurova kwemoyo zvisina kujairika izvo zvinogona kukonzera kupera simba kana kufa kamwe kamwe) kana imwe mhando yekusagadzikana kwemoyo kurova kana dambudziko repfungwa yemoyo. Uyezve udza chiremba wako kana uine yakaderera ropa makosi emagesium kana potasium muropa rako kana kenza yemazamu.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora deutetrabenazine, fonera chiremba wako.
  • iwe unofanirwa kuziva kuti deutetrabenazine inogona kukuwisira iwe kana kukonzera kuneta. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.
  • iwe unofanirwa kuziva kuti doro rinogona kuwedzera kuhope dzinokonzerwa nemushonga uyu.Usanwa doro uchitora deutetrabenazine.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana ukarasikirwa nekutora deutetrabenazine kweinopfuura vhiki, taura nachiremba wako usati watanga kuitora zvakare. Iwe uchafanirwa kutangazve kuitora iyo pazasi muyero.

Deutetrabenazine inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • manyoka
  • kuvimbiswa
  • muromo wakaoma
  • kuneta
  • kurwadziwa kana kupisa pamusoro pekuita weti
  • kukuvadza
  • chirwere chepamusoro chekufema

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona.

  • fivha, kudikitira, kuvhiringidzika, kukurumidza kana kusarongeka kwemoyo, uye kuomarara kwemhasuru
  • kubvunda, kuomarara, kana kunetsekana kufamba kana kuchengeta bharanzi
  • kudonha
  • kusagadzikana kana kukurumidza kurova kwemoyo
  • kufenda

Deutetrabenazine inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nechiedza, kupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • kumonyanisa kana kufambisa kufamba
  • kukurumidza kweziso kufamba
  • kusvotwa
  • kurutsa
  • vangadikitira
  • kunyaradza
  • kuvhiringidzika
  • manyoka
  • kufungidzira (kuona chinhu kana kunzwa manzwi zvisipo)
  • kutsvuka kweganda
  • kusadzora kusingadzoreki

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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Yekupedzisira Yakagadziridzwa - 12/15/2019

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