Neratinib

Zvemukati

• Usati watora neratinib,
• Neratinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukawana chero yeizvi zviratidzo kana izvo zvakanyorwa mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Neratinib inoshandiswa kurapa imwe mhando yehormone receptor-yakanaka kenza yemazamu (kenza yemazamu inoenderana nemahormone senge estrogen kukura) muvanhu vakuru mushure mekurapwa ne trastuzumab (Herceptin) nemimwe mishonga. Neratinib inoshandiswa pamwe chete ne capecitabine (Xeloda) kurapa imwe mhando yekenza yemazamu-yakanaka kenza yemazamu kana kenza yemazamu yakapararira kune zvimwe zvikamu zvemuviri mushure mekurapwa nemimwe mishonga miviri. Neratinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.

Neratinib inouya sehwendefa kutora nemuromo. Kana neratinib inotorwa iri yoga kurapa kenza yemazamu, inowanzo kutorwa nechikafu kamwe chete pazuva kwegore rimwe. Kana neratinib inotorwa ne capecitabine kurapa kenza yemazamu yepamusoro kana kenza yemazamu yakapararira kune zvimwe zvikamu zvemuviri, inowanzo kutorwa kamwe chete zuva nezuva nechikafu pamazuva 1 kusvika 21 ezuva remazuva makumi maviri nemasere kusvika mamiriro ako achikura kana kuti uchikura. zvakakomba mhedzisiro. Tora neratinib panguva dzakatenderedza zuva rimwe nerimwe. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora neratinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Chiremba wako anogona kudzikisira muyero wako kana kwechinguva kana zvachose kumisa kurapwa kwako kweratinib panguva yekurapa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye nemhedzisiro iwe yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora neratinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora neratinib usina kutaura nachiremba wako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora neratinib,

• udza chiremba wako uye wemishonga kana uri weergoria kune neratinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumapiritsi eeratinib. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe maantibhakitiriya anosanganisira ciprofloxacin (Cipro), clarithromycin (Biaxin, muPrevpac), erythromycin (EES, E-Mycin, Erythrocin), uye troleandomycin (haisisipo muU.S.); mamwe maantifungal anosanganisira clotrimazole (Mycelex), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), uye voriconazole (Vfend); aprepitant (Simbisa); bosentan (Tracleer); mamwe calcium chiteshi blockers anosanganisira diltiazem (Cardizem, Tiazac, vamwe) uye verapamil (Calan, Verelan, vamwe); cobicistat (Tybost); conivaptan (Vaprisol); crizotinib (Xalkori); cyclosporine (Gengraf, Neoral, Sandimmune); dabigatran (Pradaxa); digoxin (Lanoxin); dronedarone (Multaq); enzalutamide (Xtandi); fexofenadine (Allegra); fluvoxamine (Luvox); idelalisib (Zydelig); imatinib (Gleevec); mimwe mishonga yehepatitis C inosanganisira boceprevir (haichawanikwi muU.S., Victrelis), dasabuvir (muViekira Pak), ombitasvir (muTechnivie, muViekira XR), uye paritaprevir (muTechnivie, muViekira XR); mimwe mishonga yehutachiona hwehutachiona hweHIV (HIV) kana kuwana immunodeficiency syndrome (AIDS) inosanganisira efavirenz (Sustiva, muAtripla), elvitegravir (muGenvoya, muStribild), etravirine (Intelence), indinavir (Crixivan), lopinavir (in Kaletra), nelfinavir (Viracept), ritonavir (Norvir, muKaletra), saquinavir (Invirase), uye tipranavir (Aptivus); mitotane (Lysodren); modafinil (Provigil); nefazodone; proton pump inhibitors senge esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), uye rabeprazole (AcipHex); rifampin (Rifadin, Rimactane, muRifater); uye mimwe mishonga yekubatwa nechisimba inosanganisira carbamazepine (Carbatrol, Epitol, Tegretol) uye phenytoin (Dilantin, Phenytek). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana neeratinib, saka ive shuwa yekuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• kana uri kutora antacid, tora kanenge maawa matatu pamberi kana maawa matatu mushure mekutora neratinib.
• kana iwe uri kutora neratinib uye mushonga wekupererwa, kuora moyo, kana maronda (H₂ blocker) senge cimetidine, famotidine (Pepcid, muAxxis), nizatidine (Axid), kana ranitidine (Zantac), tora neratinib kwemaawa maviri zvisati zvaitika kana angangoita maawa gumi mushure mekutora H₂ blocker.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe wakambove kana wakambove nechirwere chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kana iwe uronga nezve kubereka mwana. Iwe haufanire kuve nepamuviri iwe paunenge uchitora neratinib. Kana iwe uri munhukadzi, iwe uchafanirwa kutora nhumbu yekubata usati watanga kurapwa uye unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako neratinib uye kweinenge mwedzi mumwe mushure mekutora iyo yekupedzisira dosi. Kana iwe uri murume, iwe neako mukadzi mukadzi iwe unofanirwa kushandisa kuberekwa panguva yekurapa kwako neratinib uye ramba uchiita kwemwedzi mitatu mushure meyako yekupedzisira dosi. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Kana iwe ukava nepamuviri uchitora neratinib, dana chiremba wako nekukurumidza. Neratinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchi tora neratinib uye kusvika kumwedzi mumwe mushure mekupedzisira kwezita rako.
• iwe unofanirwa kuziva kuti neratinib inowanzo kukonzera manyoka, ayo anogona kuve akaomarara. Chiremba wako angangokuudza kuti utore loperamide (Imodium AD), mushonga unorwisa manyoka, kudzivirira kupera mvura (kurasikirwa nemvura yakawandisa kubva mumuviri wako) kwemazuva 56 ekutanga ekurapwa kwako neratinib. Mushure memazuva makumi mashanu nemashanu ekurapwa, chiremba wako achachinja yako loperamide dose kuitira kuti iwe uve ne1 kusvika ku2 ura kufamba zuva nezuva uchitora neratinib Chiremba wako anogona zvakare kukuudza kuti unwe zvinwiwa zvakawanda, ita shanduko mukudya kwako, kana kutora mimwe mishonga yekudzora manyoka. Fonera chiremba wako nekukasira kana uine manyoka akanyanya (anopfuura maviri ura kufamba muzuva rimwe kana manyoka asingamire) kana manyoka pamwe nekushaya simba, dzungu, kana fivha uchitora neratinib. Shevedza chiremba wako nekukasira kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona muviri

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Neratinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kurwadziwa nemudumbu
• chirungurira
• kuzvimba
• maronda emumuromo
• kurasikirwa nenzara
• kuonda
• mhino kubuda ropa
• zvipikiri zvipikiri kana shanduko
• mhasuru

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukawana chero yeizvi zviratidzo kana izvo zvakanyorwa mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza:

• yero maziso uye ganda
• weti yakasviba
• kurwadziwa kana kusagadzikana mune yekurudyi kumusoro mudumbu nzvimbo
• kuneta
• kusvotwa
• kurutsa
• mapundu
• fivha, kunetseka kuita weti, kurwadziwa kana uchiita weti, nezvimwe zviratidzo zvehutachiona

Neratinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• manyoka
• kusvotwa
• kurutsa
• kurwadziwa nemudumbu

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune neratinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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