Munyori: Janice Evans
Zuva Rekusika: 25 Chikunguru 2021
Gadziridza Zuva: 18 Mbudzi 2024
Anonim
Glipizide (Sulfonylurea) - Mechanism of Action
Vhidhiyo: Glipizide (Sulfonylurea) - Mechanism of Action

Zvemukati

Glipizide inoshandiswa pamwe nekudya uye kurovedza muviri, uye dzimwe nguva nemimwe mishonga, kurapa mhando 2 chirwere cheshuga (mamiriro umo muviri usingashandise insulin zvakajairika uye, nekudaro, haugone kudzora huwandu hweshuga muropa). Glipizide iri mukirasi yemishonga inonzi sulfonylureas. Glipizide inoderedza shuga yeropa nekukonzeresa kuti pancreas ibudise insulin (chinhu chechisikigo chinodiwa kuputsa shuga mumuviri) nekubatsira muviri kushandisa insulin zvakanaka. Mushonga uyu unongobatsira chete kudzikisa shuga yeropa muvanhu vane miviri inoburitsa insulin zvakasikwa. Glipizide haina kushandiswa kurapa rudzi rwekutanga chirwere cheshuga (mamiriro umo muviri usingaburitse insulin uye, nekudaro, haugone kudzora huwandu hweshuga muropa) kana chirwere cheshuga ketoacidosis (chakakomba mamiriro anogona kuitika kana shuga yepamusoro yeropa isina kurapwa ).

Nekufamba kwenguva, vanhu vane chirwere cheshuga uye shuga yakakwira muropa vanogona kukura zvakakomba kana kutyisidzira hupenyu, kusanganisira chirwere chemwoyo, sitiroko, matambudziko eitsvo, kukuvara kwemitsipa uye matambudziko eziso. Kutora mishonga (s), kugadzirisa mararamiro (semuenzaniso, kudya, kurovedza muviri, kurega kusvuta), uye kugara uchiongorora shuga yako yeropa kunogona kubatsira kubata chirwere cheshuga uye kugadzirisa hutano hwako. Iyi kurapa inogona zvakare kudzikisira mikana yako yekuve nekurwadziwa kwemoyo, sitiroko, kana zvimwe zvinetso zvine chekuita neshuga senge itsvo kutadza, kukuvara kwemitsipa (chiveve, kutonhora makumbo kana tsoka; kudzikira kugona bonde kune varume nevakadzi), matambudziko eziso, kusanganisira shanduko. kana kurasikirwa kwemaonero, kana chingamu chirwere. Chiremba wako nevamwe vanopa hutano vachataura newe nezvenzira yakanakisa yekurapa chirwere cheshuga.


Glipizide inouya semapiritsi uye yakawedzera-kuburitsa (refu-inoshanda) mapiritsi ekutora nemuromo. Iyo yakajairwa piritsi inowanzo kutorwa kamwe kana kupfuura pazuva, maminetsi makumi matatu pamberi pekudya kwekuseni kana kudya. Iyo yakawedzerwa-kuburitsa piritsi inowanzo kutorwa kamwe pazuva nekudya kwekuseni. Kuti ikubatsire kuyeuka kutora glipizide, tora iyo kutenderera panguva imwechete (ma) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora glipizide chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Chiremba wako angangotanga iwe pane yakaderera dosi ye glipizide uye zvishoma nezvishoma wedzera yako dose kana zvichidikanwa. Mushure mekutora glipizide kwenguva yakati, glipizide inogona kutadza kudzora shuga rako reropa sezvawakaita pakutanga kwekurapa kwako. Chiremba wako anogona kugadzirisa dhizaini yemishonga yako pazvinenge zvichidiwa kuitira kuti mushonga unyatsoshanda kwauri. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei uye kana yako shuga yeropa mhedzisiro mhedzisiro yave yakakwira kana kudzika pane zvakajairwa chero nguva panguva yekurapwa kwako.


Medza mahwendefa akawedzerwa-kuburitsa akazara. Usatsvage, kupatsanura, kana kupwanya mapiritsi.

Glipizide inobatsira kudzora shuga yeropa asi hairape chirwere cheshuga. Ramba uchitora glipizide kunyangwe iwe uchinzwa zvakanaka. Usarega kutora glipizide usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu dzimwe nguva unonyorerwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora glipizide,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune glipizide, chero mimwe mishonga, kana chero chinhu chinowanikwa mu glipizide. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura anticoagulants ('ropa rakatetepa') senge warfarin (Coumadin); asipurini uye mamwe asiri -steroidal anti-anogumbura mishonga (NSAIDs) senge ibuprofen (Advil, Motrin) uye naproxen (Aleve, Naprosyn); beta blockers senge atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), uye propranolol (Inderal); calcium chiteshi blockers senge amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, vamwe), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotine), nisold Sular), uye verapamil (Calan, Isoptin, Verelan); chloramphenicol; cimetidine (Tagamet); diuretics ('mapiritsi emvura'); fluconazole (Diflucan); hormone kutsiva kurapa uye mahormone ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, mapiritsi, uye majekiseni); insulin kana mimwe mishonga yekurapa shuga yakakwira muropa kana chirwere cheshuga; isoniazid (INH); MAO inhibitors senge isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), uye tranylcypromine (Parnate); mishonga yeasthma uye dzihwa; mishonga yekurwara kwepfungwa uye kuda kurutsa; miconazole (Monistat); niacin; muromo steroid senge dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), uye prednisone (Deltasone); phenytoin (Dilantin); probenecid (Benemid); marwadzo e-salicylate anodzora akadai se choline magnesium trisalicylate, choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, vamwe), uye salsalate (Argesic, Disalcid, Salgesic); sulfa mishonga inorwisa mabhakitiriya senge co-trimoxazole (Bactrim, Septra); sulfasalazine (Azulfidine); uye mishonga yetachiona. Uyezve ita chokwadi chekuudza chiremba wako kana wemishonga kana iwe ukarega kutora chero mishonga uchitora glipizide. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe kana wakambove nekushomeka kweG6PD (iyo nhaka nhaka inokonzeresa kukurumidza kuparadzwa kwemasero matsvuku eropa kana hemolytic anemia); kana uine hutachiona hwehomoni inosanganisira iyo adrenal, pituitary, kana thyroid gland; kana kana iwe uine moyo, itsvo, kana chirwere chechiropa. Kana iwe uri kutora iyo yakawedzerwa-kuburitsa piritsi, udza chiremba wako kana iwe uine pfupi bowel syndrome (mamiriro apo chikamu chemukati chakabviswa nekuvhiya, kukuvadzwa nechirwere, kana iwe wakaberekwa usina chikamu chematumbo ako); une kuonda kana kuvhara kwematumbo; kana kana uchiramba uine manyoka.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora glipizide, dana chiremba wako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora glipizide.
  • bvunza chiremba wako nezve kushandiswa kwakachengeteka kwezvinwiwa zvinodhaka paunenge uchitora glipizide. Doro rinogona kuita kuti mhedzisiro ye glipizide iwedzere. Kunwa doro uchitora glipizide zvakare kashoma kunogona kukonzera zviratidzo zvakaita sekutsva (kutsvuka kwechiso), kutemwa nemusoro, kusvotwa, kurutsa, kurwadziwa pachipfuva, kushaya simba, kuona kwakashata, kuvhiringidzika kwepfungwa, kudikitira, kudzipa, kunetseka kufema, uye kunetseka.
  • ronga kudzivirira kudzivirirwa zvisina kufanira kana kwenguva yakareba kune chezuva uye kupfeka mbatya dzekudzivirira, magirazi ezuva, uye sunscreen. Glipizide inogona kuita kuti ganda rako ribate chiedza chezuva.
  • bvunza chiremba wako zvekuita kana iwe ukarwara, ukava nehutachiona kana fivha, ukawana kushushikana kusingawanzo, kana kukuvara. Aya mamiriro anogona kukanganisa shuga yako yeropa uye huwandu hwe glipizide iwe yaungangoda.

Ive neshuwa yekutevera zvese zvekurovedza muviri uye zvekudya zvinokurudzirwa zvakaitwa nachiremba wako kana wezvekudya. Zvakakosha kudya chikafu chine hutano, kurovedza muviri nguva dzose, uye kuonda kana zvichidikanwa.


Usati watanga kutora glipizide, bvunza iwe chiremba zvaunofanira kuita kana ukakanganwa kutora dose. Nyora madhairekisheni pasi kuti iwe ugone kunongedzera kwavari gare gare.

Semitemo yakajairwa, tora iyo yakarasika dhizai nekukurumidza kana uchinge uchayeuka izvozvo. Kana ingangove inguva yeiyo inotevera dosi, ruka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Mushonga uyu unogona kukonzera shanduko muropa rako shuga. Iwe unofanirwa kuziva zviratidzo zveshuga yakadzika uye yakakwira yeropa uye zvekuita kana iwe uine izvi zviratidzo.

Glipizide inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • manyoka
  • gasi
  • kunzwa jittery
  • dzungu
  • kuzunza kusingadzoreki nhengo yemuviri
  • ganda rakatsvuka kana rinonamira
  • mapundu
  • mikoko
  • mhoni

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

  • yero yeganda kana maziso
  • zvituru-zvine zvituru
  • weti yakasviba
  • kurwadziwa kumusoro kwepamusoro chikamu chedumbu
  • kupwanya kusingawanzo kana kubuda ropa
  • kupindwa nechando
  • huro inorwadza

Glipizide inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Mune kumwe kuongorora, vanhu vakatora mushonga wakafanana ne glipizide kurapa chirwere chavo cheshuga vaigona kufa nematambudziko emoyo kupfuura vanhu vaibatwa ne insulin uye dhayeti shanduko. Taura nachiremba wako nezve njodzi dzekutora glipizide.

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira hypoglycemia zviratidzo pamwe neinotevera:

  • pfari
  • kurasikirwa kwekuziva

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Yako shuga yeropa uye weti shuga mazinga anofanira kuongororwa nguva nenguva kuti uone mhinduro yako kune glipizide. Chiremba wako anogona kuraira mamwe bvunzo bvunzo, kusanganisira glycosylated hemoglobin (HbA1c), kuti utarise mhinduro yako kune glipizide. Chiremba wako anokuudzawo maitiro ekutarisa mhinduro yako kumushonga uyu nekuyera ropa rako kana weti shuga pamusha. Tevedza rairo idzi zvakanyatsonaka.

Kana iwe uri kutora akawedzeredzwa-kuburitsa mapiritsi iwe unogona kuona chimwe chinhu chinotaridzika kunge piritsi mune yako ura kufamba. Iri rinongova ndiro remahwendefa risina chinhu, uye izvi hazvireve kuti hauna kuwana dhosi rako rakazara remushonga.

Iwe unofanirwa kugara uchipfeka cheshuga chitupa chiziviso kuti uve nechokwadi chekuti unowana kurapwa kwakakodzera mune emergency.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Glucotrol®
  • Glucotrol® XL
  • Metaglip® (iine Glipizide, Metformin)

Ichi chigadzirwa chakapiswa hachisisiri pamusika. Dzimwe nzira dzinogona kuwanikwa.

Yekupedzisira Yakagadziridzwa - 10/15/2017

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