Hepatosplenomegaly: Izvo Zvaunofanirwa Kuziva

Zvemukati

• Basa rechiropa uye spleen
• Zviratidzo
• Zvinokonzera uye njodzi zviitiko
• Zvirwere
• Hematological zvirwere
• Zvirwere zvemetabolic
• Mamwe mamiriro
• Muvana
• Kuongorora
• Matambudziko
• Kurapa
• Outlook
• Kudzivirira

Mhedziso

Hepatosplenomegaly (HPM) kusagadzikana uko chiropa uye chirwatata chinozvimba kupfuura saizi yavo, nekuda kwechimwe chezvikonzero zvakawanda.

Zita rechimiro ichi - hepatosplenomegaly - rinobva mumazwi maviri anoisanganisira:

• hepatomegaly: kuzvimba kana kuwedzera kwechiropa
• splenomegaly: kuzvimba kana kuwedzera kwepleen

Haasi ese kesi dzeHPM dzakanyanya. Zvimwe zvinogona kujekeswa nekupindira kushoma. Nekudaro, HPM inogona kuratidza dambudziko rakakomba, senge lysosomal chengetedzo kusagadzikana kana gomarara.

Basa rechiropa uye spleen

Chiropa chine akasiyana mabasa kusanganisira detoxifying ropa rako, synthesizing mapuroteni, uye kurwisa hutachiona. Iyo zvakare ine chikamu chakakosha mukugadzira ese maamino acids uye bile munyu.

Muviri wako unoda simbi kuti ibudise masero matsvuku eropa, uye chiropa chako chinogadzira uye chinochengeta icho iron. Zvichida chinonyanya kuzivikanwa chemabasa echiropa chako kugadzirisa kwetsvina yemuviri wako, iyo inogona kuburitswa.

Iyo spleen imwe yemitezo yemuviri wako iyo, nekuwanda, isinganzwisisike nevanhu vazhinji. Iyo spleen ine nzvimbo yakakosha mune yako immune system. Inobatsira iyo kuziva utachiona, ari mabhakitiriya, mavairasi, kana tupukanana tunokwanisa kukonzera zvirwere. Zvino zvinobva zvagadzira masoja ekudzivirira chirwere.

Yako spleen inonatsawo ropa uye inoumbwa mutsvuku uye chena pulp inodiwa kugadzira uye kuchenesa masero eropa. Dzidza zvakatonyanya nezve spleen.

Zviratidzo

Vanhu vane hepatosplenomegaly vanogona kutaura chimwe kana zvimwe zvezviratidzo zvinotevera:

• kuneta
• kurwadziwa

Zvimwe zviratidzo, zvingave zvakanyanya, zvinosanganisira:

• kurwadziwa mudumbu mudenga repamusoro-kurudyi
• unyoro munzvimbo chaiyo yedumbu
• kusvotwa uye kurutsa
• kuzvimba kwedumbu
• kupindwa nechando
• kuramba uchichiva
• jaundice, inoratidzwa neziso reyero uye ganda
• weti yakasviba
• chevhu-chitsvuku

Zvinokonzera uye njodzi zviitiko

Hepatomegaly njodzi dzinosanganisira:

• kufutisa
• kupindwa muropa nedoro
• gomarara rechiropa
• hepatitis
• chirwere cheshuga
• cholesterol yakawanda

Splenomegaly inokonzerwa nehepatomegaly inenge makumi matatu muzana yenguva. Pane zvakawanda zvakasiyana zvikonzero zvechiropa chirwere:

Zvirwere

• acute hutachiona hepatitis
• hutachiona mononucleosis, inozivikanwawo seglandular fever kana "chirwere chekutsvoda" uye chinokonzerwa nehutachiona hweEpstein-Barr
• cytomegalovirus, mamiriro ari mu herpes hutachiona mhuri
• brucellosis, hutachiona hunopfuudzwa kuburikidza nechikafu chakasvibiswa kana kusangana nemhuka ine hutachiona
• malaria, chirwere chinotakurwa neumhutu chinogona kutyisidzira hupenyu
• leishmaniasis, chirwere chinokonzerwa nehutachiona Leishmania uye kupararira kuburikidza nekurumwa kwejecha nhunzi
• schistosomiasis, iyo inokonzereswa nehonye inouraya utachiona kana ura
• septicemic fever, iyo inokonzerwa ne Yersinia pestis hutachiona uye inogona kutyisidzira hupenyu

Hematological zvirwere

• myeloproliferative kusagadzikana, umo mwongo wemapfupa unoburitsa masero akawandisa
• leukemia, kana kenza yemongo wemapfupa
• lymphoma, kana bundu reropa reropa rinobva mumasero eropa
• sickle cell anemia, chirwere cheropa rinowanikwa muvana umo masero ehemoglobin asingakwanise kuendesa oxygen
• thalassemia, chirwere cheropa chakagarwa nhaka umo hemoglobin inogadzirwa zvisina kujairika
• myelofibrosis, kenza isingawanzoyeki yemongo wemapfupa

Zvirwere zvemetabolic

• Niemann-Pick chirwere, chirwere chakakomba chemagetsi chinosanganisira kuwanda kwemafuta mumasero
• Chirwere cheGaucher, chibereko chinokonzera kuunganidzwa kwemafuta munhengo dzakasiyana nemaseru
• Hurler syndrome, chirwere chemagene chinowedzera njodzi yekufa kwekutanga kuburikidza nekukuvara kwemitezo

Mamwe mamiriro

• chisingaperi chiropa chirwere, kusanganisira chisingaperi chinoshanda hepatitis
• amyloidosis, isingawanzo, isina kujairika kuunganidzwa kwemapuroteni akapetwa
• systemic lupus erythematosus, iyo yakajairika fomu ye autoimmune chirwere lupus
• sarcoidosis, mamiriro ayo masero ekuputira anoonekwa mune dzakasiyana nhengo
• trypanosomiasis, chirwere chinopararira chinoparadzirwa kuburikidza nekurumwa kwenhunzi ine hutachiona
• akawanda sulfatase kushomeka, kushomeka kwe enzyme kushomeka
• osteopetrosis, chirwere chisingawanzoitiki chakagara nhaka umo mapfupa akaomarara uye akaomarara kupfuura zvakajairwa

Muvana

Zvinowanzoitika zvikonzero zvehepatosplenomegaly muvana zvinogona kupfupikiswa seinotevera:

• vacheche: matambudziko ekuchengetedza uye thalassemia
• vacheche: chiropa hachikwanise kugadzirisa glucocerebroside, izvo zvinogona kukonzeresa kukuvadza kwakanyanya kune yepakati tsinga system
• vana vakura: malaria, kala azar, enteric fever, uye sepsis

Kuongorora

Aya ndiwo akati wandei ebvunzo izvo chiremba wako anogona kuraira kuti ubatsire kunyatso tsanangudza ye hepatosplenomegaly. Izvi ndeizvi:

• iyo Ultrasound, iyo inowanzo kurudzirwa mushure memuviri wedumbu unowanikwa panguva yekuongorora kwemuviri
• CT scan, iyo inogona kuburitsa yakawedzera chiropa kana spleen pamwe nenhengo dzakatenderedza
• kuongororwa kweropa, kusanganisira iro rekuyedza basa rekuyera uye kuyedza kweropa
• MRI scan kuti isimbise kuongororwa mushure mekuongororwa kwemuviri

Matambudziko

Matambudziko akajairika ehepatosplenomegaly ndeaya:

• kubuda ropa
• ropa muzvigaro
• ropa mumarutsi
• chiropa kutadza
• encephalopathy

Kurapa

Mishonga yekurapa hepatosplenomegaly inogona kusiyana kubva pamunhu kuenda kune munhu zvichienderana nechakakonzera mamiriro acho.

Nekudaro, iyo yakanakisa nzira yechiito kwauri ndeyekutaura nachiremba wako nezve chirwere chako uye kurudziro yekurapa.

Ivo vanogona kupa zano:

• Kuita shanduko yemararamiro mukutaurirana nachiremba wako. Zvinangwa zvako zvinofanirwa kunge kuri kurega kunwa kana, zvirinani, kudzikisa kunwa kwako doro zvakanyanya sezvinobvira; kurovedza muviri nguva dzose sezvaunokwanisa; uye unakirwe nekudya kwakanaka. Heano mamwe matipi ekunamatira nedhayeti ine hutano.
• Zorora, hydration, uye mishonga. Humwe hutachiona husina kusimba hunotungamira kune hepatosplenomegaly hunogona kurapwa nemishonga yakakodzera uye zororo uchiona kuti haupere simba. Kana iwe uine chirwere chinotapukira, kurapwa kwako kuchave kwakapetwa kaviri: mishonga yekurerutsa zviratidzo uye chaiyo mishonga yekubvisa hutachiona hutachiona.
• Cancer kurapwa. Kana iyo yakakonzera kenza, iwe unoda kurapwa kwakakodzera kunogona kusanganisira chemotherapy, radiotherapy, uye kuvhiya kubvisa bundu.
• Chiropa chinotamisa. Kana yako kesi iri yakaoma, sekunge uri muzvikamu zvekupedzisira zvecirrhosis, ungangoda kuisirwa chiropa. Dzidza izvo chokwadi nezvechiropa kuisirwa.

Outlook

Nekuda kwezvakasiyana siyana zvezvikonzero, hepatosplenomegaly haina kana chaicho chakabuda. Mamiriro ako ezvinhu anoenderana nezvinhu zvakasiyana, zvinosanganisira chikonzero, kukomba, uye kurapwa kwaunowana.

Iyo yekutanga HPM inoonekwa nekurapwa, zvirinani. Ona chiremba wako kana iwe ukaona zvisingawanzo zviratidzo kana kufungidzira kuti chimwe chinhu chakanganisika.

Kudzivirira

Nekuti izvo zvinokonzera hepatosplenomegaly zvakasiyana kwazvo, hazvigone kudzivirirwa nguva dzose. Nekudaro, hupenyu hune hutano hunogona kungobatsira chete. Dzivisa doro, tora maekisesaizi akawanda, uye idya chikafu chine hutano kubatsira kubatsira kudzikisira yakawanda yezvinhu zvakajairika zvine njodzi.