17-hydroxycorticosteroids weti bvunzo

Iyo 17-hydroxycorticosteroids (17-OHCS) bvunzo inoyera mwero we17-OHCS mumurini.

Iyo 24-awa weti sampuro inodiwa. Iwe unozofanirwa kutora weti yako pamusoro pemaawa makumi maviri nemana. Anopa hutano hwako anokuudza kuti ungaita sei izvi. Tevera mirairo chaizvo.

Anokupa anokuraira, kana zvichidikanwa, kumisa mishonga inogona kukanganisa bvunzo. Izvi zvinogona kusanganisira:

• Mapiritsi ekudzivirira kuberekwa ane estrogen
• Mimwe mishonga inorwisa mabhakitiriya
• Glucocorticoids

Muedzo unosanganisira kungoita weti chaiyo. Iko hakuna kusagadzikana.

17-OHCS chigadzirwa chinogadzirwa apo chiropa uye mamwe maturusi emuviri anoputsa steroid kemikari cortisol.

Bvunzo iyi inogona kubatsira kuona kana muviri uri kuburitsa yakawandisa cortisol. Muedzo unogona kushandiswa kuongorora Cushing syndrome. Ichi chirwere chinowanzoitika kana muviri uine chinogara chakakwirira checortisol.

Iyo weti vhoriyamu uye weti creatinine zvinowanzoitwa pamwe ne17-OHCS bvunzo panguva imwe chete. Izvi zvinobatsira mupiki kududzira bvunzo.

Uyu muedzo hauitwe kazhinji izvozvi. Iko yemahara cortisol weti bvunzo iri nani kuongorora bvunzo yeCushing chirwere.

Zvakajairwa tsika:

• Murume: 3 kusvika 9 mg / 24 maawa (8.3 kusvika 25 tomol / 24 maawa)
• Mukadzi: 2 kusvika 8 mg / 24 maawa (5.5 kusvika 22 µmol / 24 maawa)

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhu anoshandisa zviyero zvakasiyana kana kuyedza akasiyana sampuli. Taura nemupi wako nezve zvinorehwa nemimwe miedzo yako.

Iyo yepamusoro kupfuura yakajairwa nhanho ye17-OHCS inogona kuratidza:

• Mhando yeCushing syndrome inokonzerwa nebundu mune adrenal gland inogadzira cortisol
• Kushungurudzika
• Kurapa kweHydrocortisone
• Kushaya zvokudya zvinovaka muviri
• Kufutisa
• Kubata pamuviri
• Chikonzero chehormoni chekukwirisa kweropa
• Kunyanya kunetseka mumuviri kana mupfungwa
• Bundu mupituitary gland kana kumwe kunhu mumuviri unoburitsa hormone inonzi adrenocorticotropic hormone (ACTH)

Iyo yakaderera pane yakasarudzika nhanho ye17-OHCS inogona kuratidza:

• Adrenal gland haasi kuburitsa akakwana mahormone avo
• Pituitary gland haisi kuburitsa yakaringana mahormone ayo
• Nhaka yekushaya enzyme
• Kuvhiyiwa kwakapfuura kubvisa adrenal gland

Kuita weti inodarika matatu litita pazuva (polyuria) kunogona kuita kuti mhedzisiro yemuyedzo ive yakakwira kunyangwe kugadzirwa kwecortisol kuri kwakajairika

Iko hakuna njodzi nemuedzo uyu.

17-OH corticosteroids; 17-OHCS

Chernecky CC, Berger BJ. 17-hydroxycorticosteroids (17-OHCS) - 24-awa weti. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 659-660.

Juszczak A, Morris DG, Grossman AB, Nieman LK. Cushing's chirwere. Muna: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Vakuru uye Chiremba. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits.